Antibody data
- Antibody Data
- Antigen structure
- References [205]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
- Flow cytometry [1]
- Other assay [14]
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Validation data
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- Product number
- MA5-14524 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- CD3e Monoclonal Antibody (SP7)
- Antibody type
- Monoclonal
- Antigen
- Synthetic peptide
- Description
- MA5-14524 targets CD3E in IHC (P), FACS, and Western blot applications and shows reactivity with human and mouse samples.
- Antibody clone number
- SP7
- Concentration
- Conc. Not Determined
Submitted references AMP-activated protein kinase alpha1 promotes tumor development via FOXP3 elevation in tumor-infiltrating Treg cells.
Tumour cell apoptosis modulates the colorectal cancer immune microenvironment via interleukin-8-dependent neutrophil recruitment.
Molecular Examination of Differentially Expressed Genes in the Brains of Experimental Autoimmune Encephalomyelitis Mice Post Herceptin Treatment.
Molecular evidence suggesting the persistence of residual SARS-CoV-2 and immune responses in the placentas of pregnant patients recovered from COVID-19.
Role of epidermal growth factor receptor inhibitor-induced interferon pathway signaling in the head and neck squamous cell carcinoma therapeutic response.
Synergistic anti-tumor efficacy of oncolytic influenza viruses and B7-H3 immune- checkpoint inhibitors against IC-resistant lung cancers.
T-bet+ Memory B Cells Link to Local Cross-Reactive IgG upon Human Rhinovirus Infection.
Aggressive Mammary Cancers Lacking Lymphocytic Infiltration Arise in Irradiated Mice and Can Be Prevented by Dietary Intervention.
PTEN (Phosphatase and Tensin Homolog) Protects Against Ang II (Angiotensin II)-Induced Pathological Vascular Fibrosis and Remodeling-Brief Report.
Statin as anti-cancer therapy in autochthonous T-lymphomas expressing stabilized gain-of-function mutant p53 proteins.
Cancer Cell-Intrinsic Expression of MHC Class II Regulates the Immune Microenvironment and Response to Anti-PD-1 Therapy in Lung Adenocarcinoma.
Prognostic Value of the Neo-Immunoscore in Renal Cell Carcinoma.
Tumor-intrinsic response to IFNγ shapes the tumor microenvironment and anti-PD-1 response in NSCLC.
Targeted overexpression of prostacyclin synthase inhibits lung tumor progression by recruiting CD4+ T lymphocytes in tumors that express MHC class II.
Differential requirements for the canonical NF-κB transcription factors c-REL and RELA during the generation and activation of mature B cells.
Genomic Amplification of CD274 (PD-L1) in Small-Cell Lung Cancer.
In Situ Characterization of Tissue-Resident Immune Cells by MALDI Mass Spectrometry Imaging.
Genomic binding of PAX8-PPARG fusion protein regulates cancer-related pathways and alters the immune landscape of thyroid cancer.
Complement C3 on microglial clusters in multiple sclerosis occur in chronic but not acute disease: Implication for disease pathogenesis.
A method for histopathological study of the multifocal nature of spinal cord lesions in murine experimental autoimmune encephalomyelitis.
A Gain-Of-Function Mutation in the Plcg2 Gene Protects Mice from Helicobacter felis-Induced Gastric MALT Lymphoma.
Isoform-Specific Effects of Wild-Type Ras Genes on Carcinogen-Induced Lung Tumorigenesis in Mice.
Tumor-infiltrating lymphocyte subsets and tertiary lymphoid structures in pulmonary metastases from colorectal cancer.
C-C Motif Chemokine 5 Attenuates Angiotensin II-Dependent Kidney Injury by Limiting Renal Macrophage Infiltration.
Nontuberculous mycobacterial infection with concurrent IgG4-related lymphadenopathy.
Heat-killed Staphylococcus aureus reduces atherosclerosis by inducing anti-inflammatory macrophages.
Dendritic cell-derived VEGF-A plays a role in inflammatory angiogenesis of human secondary lymphoid organs and is driven by the coordinated activation of multiple transcription factors.
Renal rescue of dopamine D2 receptor function reverses renal injury and high blood pressure.
CaMKII is a RIP3 substrate mediating ischemia- and oxidative stress-induced myocardial necroptosis.
Monoclonal antibodies specific for oncofetal antigen--immature laminin receptor protein: Effects on tumor growth and spread in two murine models.
Induction of colorectal cancer in mice and histomorphometric evaluation of tumors.
Periluminal Distribution of HIV-Binding Target Cells and Gp340 in the Oral, Cervical and Sigmoid/Rectal Mucosae: A Mapping Study.
The Novel Extracellular Cyclophilin A (CyPA) - Inhibitor MM284 Reduces Myocardial Inflammation and Remodeling in a Mouse Model of Troponin I -Induced Myocarditis.
Tumor-Infiltrating Immune Cells Are Associated With Prognosis of Gastric Cancer.
CXCR2-CXCL1 axis is correlated with neutrophil infiltration and predicts a poor prognosis in hepatocellular carcinoma.
Autoimmune encephalitis in humans: how closely does it reflect multiple sclerosis ?
Harnessing high density lipoproteins to block transforming growth factor beta and to inhibit the growth of liver tumor metastases.
Comparative characterization of stroma cells and ductal epithelium in chronic pancreatitis and pancreatic ductal adenocarcinoma.
EGFRvIII-specific chimeric antigen receptor T cells migrate to and kill tumor deposits infiltrating the brain parenchyma in an invasive xenograft model of glioblastoma.
Regulation of proximal T cell receptor signaling and tolerance induction by deubiquitinase Usp9X.
The oxysterol receptor LXRβ protects against DSS- and TNBS-induced colitis in mice.
Liquid-based cytologic findings of solitary extramedullary plasmacytoma in thyroid: a case report identified with fine-needle aspiration cytology.
CD30(+) extranodal natural killer/T-cell lymphoma mimicking phlegmonous myositis: A case report.
Colonic mucosal immune activity in irritable bowel syndrome: comparison with healthy controls and patients with ulcerative colitis.
Functional validation of a human CAPN5 exome variant by lentiviral transduction into mouse retina.
Differential expression of BAFF and its receptors in discoid lupus erythematosus patients.
Novel bispecific antibodies increase γδ T-cell cytotoxicity against pancreatic cancer cells.
Mouse models of mantle cell lymphoma, complex changes in gene expression and phenotype of engrafted MCL cells: implications for preclinical research.
Bioactive nanocomposite for chest-wall replacement: Cellular response in a murine model.
Metastatic growth progression caused by PSGL-1-mediated recruitment of monocytes to metastatic sites.
Multiple sclerosis deep grey matter: the relation between demyelination, neurodegeneration, inflammation and iron.
Epstein-Barr virus-associated adrenal smooth muscle tumors and disseminated diffuse large B-cell lymphoma in a child with common variable immunodeficiency: a case report and review of the literature.
Expression of indoleamine 2,3-dioxygenase and infiltration of FOXP3+ regulatory T cells are associated with aggressive features of papillary thyroid microcarcinoma.
Constitutive expression of murine c-FLIPR causes autoimmunity in aged mice.
The chemokine CCL3 promotes experimental liver fibrosis in mice.
Immune cells from SR/CR mice induce the regression of established tumors in BALB/c and C57BL/6 mice.
Occurrence of nodular lymphocyte-predominant hodgkin lymphoma in hermansky-pudlak type 2 syndrome is associated to natural killer and natural killer T cell defects.
Histopathological, immunophenotypic and clinical particularities and evolution of a case of hepatosplenic T-cell lymphoma in transformation to leukemia.
A histological analysis of gingival condition associated with orthodontic treatment.
Ezrin/Radixin/Moesin proteins and flotillins cooperate to promote uropod formation in T cells.
The p53 Codon 72 Polymorphism Modifies the Cellular Response to Inflammatory Challenge in the Liver.
Upregulation of adenosine kinase in Rasmussen encephalitis.
Corelation of lymphocytic infiltrates with the prognosis of recurrent colo-rectal cancer.
Neutralization of ocular surface TNF-α reduces ocular surface and lacrimal gland inflammation induced by in vivo dry eye.
Humanized mice, a new model to study the influence of drug treatment on neonatal sepsis.
Intrastriatal injection of interleukin-1 beta triggers the formation of neuromyelitis optica-like lesions in NMO-IgG seropositive rats.
Human Immunodeficiency Virus (HIV)-Negative and Human Herpes Virus-8 (HHV-8)-Positive Primary Effusion Lymphoma: A Case Report and Review of the Literature.
Clinicopathological features of aggressive B-cell lymphomas including B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell and Burkitt lymphomas: a study of 44 patients from Argentina.
Disease-specific molecular events in cortical multiple sclerosis lesions.
Characterization of the inflammatory response to solid cancer metastases in the human brain.
Expression of FOXP3, CD68, and CD20 at diagnosis in the microenvironment of classical Hodgkin lymphoma is predictive of outcome.
Blastic plasmacytoid dendritic cell neoplasm with leukemic presentation: an Italian multicenter study.
Wiskott-Aldrich syndrome protein-mediated actin dynamics control type-I interferon production in plasmacytoid dendritic cells.
Microvascular proliferations in arteriovenous malformations relate to high-flow characteristics, inflammation, and previous therapeutic embolization of the lesion.
Clinicopathology, immunophenotype, T cell receptor gene rearrangement, Epstein-Barr virus status and p53 gene mutation of cutaneous extranodal NK/T-cell lymphoma, nasal-type.
Alcohol based fixatives provide excellent tissue morphology, protein immunoreactivity and RNA integrity in paraffin embedded tissue specimens.
Lymphotoxin, but not TNF, is required for prion invasion of lymph nodes.
Targeting melanoma metastasis and immunosuppression with a new mode of melanoma inhibitory activity (MIA) protein inhibition.
Invariant NKT cells drive hepatic cytokinic microenvironment favoring efficient granuloma formation and early control of Leishmania donovani infection.
VR09 cell line: an EBV-positive lymphoblastoid cell line with in vivo characteristics of diffuse large B cell lymphoma of activated B-cell type.
Targeting BRAFV600E in an inducible murine model of melanoma.
Rats deficient for p53 are susceptible to spontaneous and carcinogen-induced tumorigenesis.
Congenital cytomegalovirus infection: patterns of fetal brain damage.
The TNF family member APRIL promotes colorectal tumorigenesis.
Endothelial insulin receptor expression in human atherosclerotic plaques: linking micro- and macrovascular disease in diabetes?
The development and fate of follicular helper T cells defined by an IL-21 reporter mouse.
Mucosal immune cell numbers and visceral sensitivity in patients with irritable bowel syndrome: is there any relationship?
Cyclophilin A affects inflammation, virus elimination and myocardial fibrosis in coxsackievirus B3-induced myocarditis.
Chlamydia psittaci-negative ocular adnexal marginal zone B-cell lymphomas have biased VH4-34 immunoglobulin gene expression and proliferate in a distinct inflammatory environment.
Lymphoid tissue damage in HIV-1 infection depletes naïve T cells and limits T cell reconstitution after antiretroviral therapy.
Electrospun small-diameter polyurethane vascular grafts: ingrowth and differentiation of vascular-specific host cells.
Folliculocentric B-cell-rich follicular dendritic cells sarcoma: a hitherto unreported morphological variant mimicking lymphoproliferative disorders.
Tubular lesions predict renal outcome in antineutrophil cytoplasmic antibody-associated glomerulonephritis after rituximab therapy.
Leukocyte composition of human breast cancer.
BCL10 down-regulation in peripheral T-cell lymphomas.
Bioactive acellular implant induces angiogenesis and adipogenesis and sustained soft tissue restoration in vivo.
The TGF-β co-receptor endoglin regulates macrophage infiltration and cytokine production in the irradiated mouse kidney.
Th17 cells induce a distinct graft rejection response that does not require IL-17A.
Expression of B-RAF V600E in type II pneumocytes causes abnormalities in alveolar formation, airspace enlargement and tumor formation in mice.
Intratumoral Immune Responses Can Distinguish New Primary and True Recurrence Types of Ipsilateral Breast Tumor Recurrences (IBTR).
Extraintestinal Crohn's disease mimicking autoimmune inner ear disease: a histopathological approach.
Tumor-infiltrating lymphocytes predict response to anthracycline-based chemotherapy in estrogen receptor-negative breast cancer.
Forkhead box protein P1 as a downstream target of transforming growth factor-β induces collagen synthesis and correlates with a more stable plaque phenotype.
Myocardial pathology in pulmonary thromboembolism.
MART-1 is a reliable melanocytic marker in lichen planus-like keratosis: a study on 70 cases.
Efficient transgene expression from naked DNA delivered into an arterio-venous fistula model for kidney dialysis.
Depletion of CD4⁺ T cells abrogates post-peak decline of viremia in SIV-infected rhesus macaques.
High frequency of development of B cell lymphoproliferation and diffuse large B cell lymphoma in Dbl knock-in mice.
Specific maternal microchimeric T cells targeting fetal antigens in β cells predispose to auto-immune diabetes in the child.
Innate and adaptive immunity in amyotrophic lateral sclerosis: evidence of complement activation.
Analysis of IL-17(+) cells in facet joints of patients with spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the Th17-mediated adaptive immune response.
Distribution of intrahepatic T, NK and CD3(+)CD56(+)NKT cells alters after liver transplantation: Shift from innate to adaptive immunity?
Composite lymphoma in the anterior mediastinum: a case report and review of the literature.
Identification of carotid 'vulnerable plaque' by contrast-enhanced ultrasonography: correlation with plaque histology, symptoms and cerebral computed tomography.
The prolactin receptor is expressed in macrophages within human carotid atherosclerotic plaques: a role for prolactin in atherogenesis?
Diffuse large B-cell lymphoma involving the central nervous system.
Sun exposure induces rapid immunological changes in skin and peripheral blood in patients with psoriasis.
Histopathologic-based prognostic factors of colorectal cancers are associated with the state of the local immune reaction.
Essential role of E3 ubiquitin ligase activity in Cbl-b-regulated T cell functions.
Expression of the embryological morphogen Nodal in stage III/IV melanoma.
Putting the brakes on mammary tumorigenesis: loss of STAT1 predisposes to intraepithelial neoplasias.
Cytomegalovirus infection presenting as isolated inflammatory polyps of the gastrointestinal tract.
Study of cellular immune response against Hepatitis E virus (HEV).
Functional CD47/signal regulatory protein alpha (SIRP(alpha)) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo.
RNA sensor-induced type I IFN prevents diabetes caused by a β cell-tropic virus in mice.
Primary central nervous system lymphoma: a study of clinicopathological features and trend in western India.
Spatial differences in the presence of FOXP3+ and GranzymeB+ T cells between the intra- and extravascular compartments in renal allograft vasculopathy.
Pediatric lymphomas in Brazil.
Primary central nervous system peripheral T-cell lymphoma in a child.
T-cell leukemia 1 expression in nodal Epstein-Barr virus-negative diffuse large B-cell lymphoma and primary mediastinal B-cell lymphoma.
T cell density and location can influence the prognosis of ovarian cancer.
Permissive environment for B-cell maturation in myositis muscle in the absence of B-cell follicles.
Demyelination versus remyelination in progressive multiple sclerosis.
CD34+ cells from AML with mutated NPM1 harbor cytoplasmic mutated nucleophosmin and generate leukemia in immunocompromised mice.
Primary plasmacytoma of the cervix in a 21-year-old female patient.
Interferon gamma-induced human guanylate binding protein 1 inhibits mammary tumor growth in mice.
Host-detrimental role of Esx-1-mediated inflammasome activation in mycobacterial infection.
The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma.
Differential expression of interleukin-17 family cytokines in intact and complicated human atherosclerotic plaques.
Human peripheral lymphoid tissues contain autoimmune regulator-expressing dendritic cells.
Axonal prion protein is required for peripheral myelin maintenance.
Myxoid cystitis with "chordoid" lymphocytes: another mimic of invasive urothelial carcinoma.
Foxp3+ regulatory T cells and related cytokines differentially expressed in plaque vs. guttate psoriasis vulgaris.
3D visualization of HIV transfer at the virological synapse between dendritic cells and T cells.
Pseudo-placentational endometrial cysts in a bitch.
Clinical significance and regulation of the costimulatory molecule B7-H3 in human colorectal carcinoma.
Ablation of Dicer from murine Schwann cells increases their proliferation while blocking myelination.
Biomolecular network reconstruction identifies T-cell homing factors associated with survival in colorectal cancer.
Dendritic cell-mediated-immunization with xenogenic PrP and adenoviral vectors breaks tolerance and prolongs mice survival against experimental scrapie.
Cutaneous distribution of plasmacytoid dendritic cells in lupus erythematosus. Selective tropism at the site of epithelial apoptotic damage.
Repetitive immunization enhances the susceptibility of mice to peripherally administered prions.
Mice deficient for CD137 ligand are predisposed to develop germinal center-derived B-cell lymphoma.
Mammary tumors with diverse immunological phenotypes show differing sensitivity to adoptively transferred CD8+ T cells lacking the Cbl-b gene.
Homeostatic proliferation of naïve CD8+ T cells depends on CD62L/L-selectin-mediated homing to peripheral LN.
Diffuse blastoid B-cell lymphoma: a histologically aggressive variant of t(14;18)-negative follicular lymphoma.
CD8+ T-cell clones dominate brain infiltrates in Rasmussen encephalitis and persist in the periphery.
Coordination of intratumoral immune reaction and human colorectal cancer recurrence.
Priming of protective T cell responses against virus-induced tumors in mice with human immune system components.
Anti-tumor activity of patient-derived NK cells after cell-based immunotherapy--a case report.
Vaccine-specific local T cell reactivity in immunotherapy-associated vitiligo in melanoma patients.
Placental endothelial cells can be productively infected by Parvovirus B19.
Primary cutaneous CD4+ small/medium-sized pleomorphic T-cell lymphoma expresses follicular T-cell markers.
Composite lymphoma: EBV-positive classic Hodgkin lymphoma and peripheral T-cell lymphoma: a case report.
Intravascular lymphocytosis in acute appendicitis: potential mimicry of chronic lymphocytic leukaemia.
What is your diagnosis? Ascites fluid from an 11-year-old dog with epigastric bulging.
Castration induces autoantibody and T cell responses that correlate with inferior outcomes in an androgen-dependent murine tumor model.
Psoriasis vs allergic contact dermatitis in palms and soles: a quantitative histologic and immunohistochemical study.
Regulatory T cells and the PD-L1/PD-1 pathway mediate immune suppression in malignant human brain tumors.
Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23-Th17 pathway.
Gaucher or pseudo-Gaucher? The challenge of several diseases colliding in a pediatric patient.
Frequent expression of multiple myeloma 1/interferon regulatory factor 4 in Burkitt lymphoma.
Plasmoblastic lymphoma associated with human immunodeficiency virus.
Local immune alterations in oral mucosa of the edentulous patients; possible cause of teeth loss?
Oncologic trogocytosis of an original stromal cells induces chemoresistance of ovarian tumours.
Tumor-infiltrating T cells correlate with NY-ESO-1-specific autoantibodies in ovarian cancer.
Expression of p63 in anaplastic large cell lymphoma but not in classical Hodgkin's lymphoma.
Rituximab-induced changes in hematolymphoid tissues found at autopsy.
The majority of cutaneous marginal zone B-cell lymphomas expresses class-switched immunoglobulins and develops in a T-helper type 2 inflammatory environment.
Temporal delay of peak T-cell immunity determines Chlamydia pneumoniae pulmonary disease in mice.
Early resolution of acute immune activation and induction of PD-1 in SIV-infected sooty mangabeys distinguishes nonpathogenic from pathogenic infection in rhesus macaques.
An inducible caspase 9 safety switch can halt cell therapy-induced autoimmune disease.
T-cell lymphomas in T-cell-specific Pten-deficient mice originate in the thymus.
Availability of activated CD4+ T cells dictates the level of viremia in naturally SIV-infected sooty mangabeys.
B lymphocyte autoimmunity in rheumatoid synovitis is independent of ectopic lymphoid neogenesis.
GVHD after chemotherapy conditioning in allogeneic transplanted mice.
N-Methyl-N-Nitrosourea (MNU): A positive control chemical for p53+/- mouse carcinogenicity studies.
Burkitt lymphoma in Brazil is characterized by geographically distinct clinicopathologic features.
Stimulation of lymphocyte responses by angiotensin II promotes kidney injury in hypertension.
Short-lived infected cells support virus replication in sooty mangabeys naturally infected with simian immunodeficiency virus: implications for AIDS pathogenesis.
Multiple immunoenzyme staining: methods and visualizations for the observation with spectral imaging.
Differential responsiveness to immunoablative therapy in refractory rheumatoid arthritis is associated with level and avidity of anti-cyclic citrullinated protein autoantibodies: a case study.
Effect of melatonin and zinc on the immune response in experimental Toxoplasma retinochoroiditis.
Immunohistochemical analysis of regulatory T cell markers FOXP3 and GITR on CD4+CD25+ T cells in normal skin and inflammatory dermatoses.
Graft-versus-host-like disease complicating thymoma: lack of AIRE expression as a cause of non-hereditary autoimmunity?
The contribution of bifunctional SkipDewax pretreatment solution, rabbit monoclonal antibodies, and polymer detection systems in immunohistochemistry.
Differential Noxa/Mcl-1 balance in peripheral versus lymph node chronic lymphocytic leukemia cells correlates with survival capacity.
Immunohistochemical analysis as a means to predict responsiveness to rituximab treatment.
Clinicopathologic findings in high-grade B-cell lymphomas with typical Burkitt morphologic features but lacking the MYC translocation.
Low numbers of FOXP3 positive regulatory T cells are present in all developmental stages of human atherosclerotic lesions.
Macrophage inhibitory cytokine 1 mediates a p53-dependent protective arrest in S phase in response to starvation for DNA precursors.
Disseminated and sustained HIV infection in CD34+ cord blood cell-transplanted Rag2-/-gamma c-/- mice.
Establishment of the MAVER-1 cell line, a model for leukemic and aggressive mantle cell lymphoma.
Chemokine receptors in the rheumatoid synovium: upregulation of CXCR5.
Intratumoral recombinant human interleukin-12 administration in head and neck squamous cell carcinoma patients modifies locoregional lymph node architecture and induces natural killer cell infiltration in the primary tumor.
Invasive inflammatory pseudotumor of uterine cervix: a case report.
An J, Ding Y, Yu C, Li J, You S, Liu Z, Song P, Zou MH
iScience 2022 Jan 21;25(1):103570
iScience 2022 Jan 21;25(1):103570
Tumour cell apoptosis modulates the colorectal cancer immune microenvironment via interleukin-8-dependent neutrophil recruitment.
Schimek V, Strasser K, Beer A, Göber S, Walterskirchen N, Brostjan C, Müller C, Bachleitner-Hofmann T, Bergmann M, Dolznig H, Oehler R
Cell death & disease 2022 Feb 4;13(2):113
Cell death & disease 2022 Feb 4;13(2):113
Molecular Examination of Differentially Expressed Genes in the Brains of Experimental Autoimmune Encephalomyelitis Mice Post Herceptin Treatment.
Al-Ani M, Elemam NM, Hachim IY, Raju TK, Muhammad JS, Hachim MY, Bendardaf R, Maghazachi AA
Journal of inflammation research 2021;14:2601-2617
Journal of inflammation research 2021;14:2601-2617
Molecular evidence suggesting the persistence of residual SARS-CoV-2 and immune responses in the placentas of pregnant patients recovered from COVID-19.
Wu H, Liao S, Wang Y, Guo M, Lin X, Wu J, Wang R, Lv D, Wu D, He M, Hu B, Long R, Peng J, Yang H, Yin H, Wang X, Huang Z, Lan K, Zhou Y, Zhang W, Xiao Z, Zhao Y, Deng D, Wang H
Cell proliferation 2021 Sep;54(9):e13091
Cell proliferation 2021 Sep;54(9):e13091
Role of epidermal growth factor receptor inhibitor-induced interferon pathway signaling in the head and neck squamous cell carcinoma therapeutic response.
Korpela SP, Hinz TK, Oweida A, Kim J, Calhoun J, Ferris R, Nemenoff RA, Karam SD, Clambey ET, Heasley LE
Journal of translational medicine 2021 Jan 23;19(1):43
Journal of translational medicine 2021 Jan 23;19(1):43
Synergistic anti-tumor efficacy of oncolytic influenza viruses and B7-H3 immune- checkpoint inhibitors against IC-resistant lung cancers.
Masemann D, Meissner R, Schied T, Lichty BD, Rapp UR, Wixler V, Ludwig S
Oncoimmunology 2021 Feb 17;10(1):1885778
Oncoimmunology 2021 Feb 17;10(1):1885778
T-bet+ Memory B Cells Link to Local Cross-Reactive IgG upon Human Rhinovirus Infection.
Eccles JD, Turner RB, Kirk NA, Muehling LM, Borish L, Steinke JW, Payne SC, Wright PW, Thacker D, Lahtinen SJ, Lehtinen MJ, Heymann PW, Woodfolk JA
Cell reports 2020 Jan 14;30(2):351-366.e7
Cell reports 2020 Jan 14;30(2):351-366.e7
Aggressive Mammary Cancers Lacking Lymphocytic Infiltration Arise in Irradiated Mice and Can Be Prevented by Dietary Intervention.
Omene C, Ma L, Moore J, Ouyang H, Illa-Bochaca I, Chou W, Patel MS, Sebastiano C, Demaria S, Mao JH, Karagoz K, Gatza ML, Barcellos-Hoff MH
Cancer immunology research 2020 Feb;8(2):217-229
Cancer immunology research 2020 Feb;8(2):217-229
PTEN (Phosphatase and Tensin Homolog) Protects Against Ang II (Angiotensin II)-Induced Pathological Vascular Fibrosis and Remodeling-Brief Report.
Lu S, Strand KA, Mutryn MF, Tucker RM, Jolly AJ, Furgeson SB, Moulton KS, Nemenoff RA, Weiser-Evans MCM
Arteriosclerosis, thrombosis, and vascular biology 2020 Feb;40(2):394-403
Arteriosclerosis, thrombosis, and vascular biology 2020 Feb;40(2):394-403
Statin as anti-cancer therapy in autochthonous T-lymphomas expressing stabilized gain-of-function mutant p53 proteins.
Tutuska K, Parrilla-Monge L, Di Cesare E, Nemajerova A, Moll UM
Cell death & disease 2020 Apr 24;11(4):274
Cell death & disease 2020 Apr 24;11(4):274
Cancer Cell-Intrinsic Expression of MHC Class II Regulates the Immune Microenvironment and Response to Anti-PD-1 Therapy in Lung Adenocarcinoma.
Johnson AM, Bullock BL, Neuwelt AJ, Poczobutt JM, Kaspar RE, Li HY, Kwak JW, Hopp K, Weiser-Evans MCM, Heasley LE, Schenk EL, Clambey ET, Nemenoff RA
Journal of immunology (Baltimore, Md. : 1950) 2020 Apr 15;204(8):2295-2307
Journal of immunology (Baltimore, Md. : 1950) 2020 Apr 15;204(8):2295-2307
Prognostic Value of the Neo-Immunoscore in Renal Cell Carcinoma.
Guo C, Zhao H, Wang Y, Bai S, Yang Z, Wei F, Ren X
Frontiers in oncology 2019;9:439
Frontiers in oncology 2019;9:439
Tumor-intrinsic response to IFNγ shapes the tumor microenvironment and anti-PD-1 response in NSCLC.
Bullock BL, Kimball AK, Poczobutt JM, Neuwelt AJ, Li HY, Johnson AM, Kwak JW, Kleczko EK, Kaspar RE, Wagner EK, Hopp K, Schenk EL, Weiser-Evans MC, Clambey ET, Nemenoff RA
Life science alliance 2019 Jun;2(3)
Life science alliance 2019 Jun;2(3)
Targeted overexpression of prostacyclin synthase inhibits lung tumor progression by recruiting CD4+ T lymphocytes in tumors that express MHC class II.
Li HY, McSharry M, Walker D, Johnson A, Kwak J, Bullock B, Neuwelt A, Poczobutt JM, Sippel TR, Keith RL, Weiser-Evans MCM, Clambey E, Nemenoff RA
Oncoimmunology 2018;7(5):e1423182
Oncoimmunology 2018;7(5):e1423182
Differential requirements for the canonical NF-κB transcription factors c-REL and RELA during the generation and activation of mature B cells.
Milanovic M, Heise N, De Silva NS, Anderson MM, Silva K, Carette A, Orelli F, Bhagat G, Klein U
Immunology and cell biology 2017 Mar;95(3):261-271
Immunology and cell biology 2017 Mar;95(3):261-271
Genomic Amplification of CD274 (PD-L1) in Small-Cell Lung Cancer.
George J, Saito M, Tsuta K, Iwakawa R, Shiraishi K, Scheel AH, Uchida S, Watanabe SI, Nishikawa R, Noguchi M, Peifer M, Jang SJ, Petersen I, Büttner R, Harris CC, Yokota J, Thomas RK, Kohno T
Clinical cancer research : an official journal of the American Association for Cancer Research 2017 Mar 1;23(5):1220-1226
Clinical cancer research : an official journal of the American Association for Cancer Research 2017 Mar 1;23(5):1220-1226
In Situ Characterization of Tissue-Resident Immune Cells by MALDI Mass Spectrometry Imaging.
Holzlechner M, Strasser K, Zareva E, Steinhäuser L, Birnleitner H, Beer A, Bergmann M, Oehler R, Marchetti-Deschmann M
Journal of proteome research 2017 Jan 6;16(1):65-76
Journal of proteome research 2017 Jan 6;16(1):65-76
Genomic binding of PAX8-PPARG fusion protein regulates cancer-related pathways and alters the immune landscape of thyroid cancer.
Zhang Y, Yu J, Grachtchouk V, Qin T, Lumeng CN, Sartor MA, Koenig RJ
Oncotarget 2017 Jan 24;8(4):5761-5773
Oncotarget 2017 Jan 24;8(4):5761-5773
Complement C3 on microglial clusters in multiple sclerosis occur in chronic but not acute disease: Implication for disease pathogenesis.
Michailidou I, Naessens DM, Hametner S, Guldenaar W, Kooi EJ, Geurts JJ, Baas F, Lassmann H, Ramaglia V
Glia 2017 Feb;65(2):264-277
Glia 2017 Feb;65(2):264-277
A method for histopathological study of the multifocal nature of spinal cord lesions in murine experimental autoimmune encephalomyelitis.
Gibson-Corley KN, Boyden AW, Leidinger MR, Lambertz AM, Ofori-Amanfo G, Naumann PW, Goeken JA, Karandikar NJ
PeerJ 2016;4:e1600
PeerJ 2016;4:e1600
A Gain-Of-Function Mutation in the Plcg2 Gene Protects Mice from Helicobacter felis-Induced Gastric MALT Lymphoma.
Gossmann J, Stolte M, Lohoff M, Yu P, Moll R, Finkernagel F, Garn H, Brendel C, Bittner A, Neubauer A, Huynh MQ
PloS one 2016;11(3):e0150411
PloS one 2016;11(3):e0150411
Isoform-Specific Effects of Wild-Type Ras Genes on Carcinogen-Induced Lung Tumorigenesis in Mice.
Weyandt JD, Carney JM, Pavlisko EN, Xu M, Counter CM
PloS one 2016;11(12):e0167205
PloS one 2016;11(12):e0167205
Tumor-infiltrating lymphocyte subsets and tertiary lymphoid structures in pulmonary metastases from colorectal cancer.
Schweiger T, Berghoff AS, Glogner C, Glueck O, Rajky O, Traxler D, Birner P, Preusser M, Klepetko W, Hoetzenecker K
Clinical & experimental metastasis 2016 Oct;33(7):727-39
Clinical & experimental metastasis 2016 Oct;33(7):727-39
C-C Motif Chemokine 5 Attenuates Angiotensin II-Dependent Kidney Injury by Limiting Renal Macrophage Infiltration.
Rudemiller NP, Patel MB, Zhang JD, Jeffs AD, Karlovich NS, Griffiths R, Kan MJ, Buckley AF, Gunn MD, Crowley SD
The American journal of pathology 2016 Nov;186(11):2846-2856
The American journal of pathology 2016 Nov;186(11):2846-2856
Nontuberculous mycobacterial infection with concurrent IgG4-related lymphadenopathy.
Liu TT, Weng SW, Wang MC, Huang WT
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2016 Mar;124(3):216-20
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2016 Mar;124(3):216-20
Heat-killed Staphylococcus aureus reduces atherosclerosis by inducing anti-inflammatory macrophages.
Frodermann V, van Duijn J, van Puijvelde GH, van Santbrink PJ, Lagraauw HM, de Vries MR, Quax PH, Bot I, Foks AC, de Jager SC, Kuiper J
Journal of internal medicine 2016 Jun;279(6):592-605
Journal of internal medicine 2016 Jun;279(6):592-605
Dendritic cell-derived VEGF-A plays a role in inflammatory angiogenesis of human secondary lymphoid organs and is driven by the coordinated activation of multiple transcription factors.
Salvi V, Vermi W, Gianello V, Lonardi S, Gagliostro V, Naldini A, Sozzani S, Bosisio D
Oncotarget 2016 Jun 28;7(26):39256-39269
Oncotarget 2016 Jun 28;7(26):39256-39269
Renal rescue of dopamine D2 receptor function reverses renal injury and high blood pressure.
Konkalmatt PR, Asico LD, Zhang Y, Yang Y, Drachenberg C, Zheng X, Han F, Jose PA, Armando I
JCI insight 2016 Jun 2;1(8)
JCI insight 2016 Jun 2;1(8)
CaMKII is a RIP3 substrate mediating ischemia- and oxidative stress-induced myocardial necroptosis.
Zhang T, Zhang Y, Cui M, Jin L, Wang Y, Lv F, Liu Y, Zheng W, Shang H, Zhang J, Zhang M, Wu H, Guo J, Zhang X, Hu X, Cao CM, Xiao RP
Nature medicine 2016 Feb;22(2):175-82
Nature medicine 2016 Feb;22(2):175-82
Monoclonal antibodies specific for oncofetal antigen--immature laminin receptor protein: Effects on tumor growth and spread in two murine models.
McClintock SD, Warner RL, Ali S, Chekuri A, Dame MK, Attili D, Knibbs RK, Aslam MN, Sinkule J, Morgan AC, Barsoum A, Smith LB, Beer DG, Johnson KJ, Varani J
Cancer biology & therapy 2015;16(5):724-32
Cancer biology & therapy 2015;16(5):724-32
Induction of colorectal cancer in mice and histomorphometric evaluation of tumors.
Crncec I, Pathria P, Svinka J, Eferl R
Methods in molecular biology (Clifton, N.J.) 2015;1267:145-64
Methods in molecular biology (Clifton, N.J.) 2015;1267:145-64
Periluminal Distribution of HIV-Binding Target Cells and Gp340 in the Oral, Cervical and Sigmoid/Rectal Mucosae: A Mapping Study.
Patyka M, Malamud D, Weissman D, Abrams WR, Kurago Z
PloS one 2015;10(7):e0132942
PloS one 2015;10(7):e0132942
The Novel Extracellular Cyclophilin A (CyPA) - Inhibitor MM284 Reduces Myocardial Inflammation and Remodeling in a Mouse Model of Troponin I -Induced Myocarditis.
Heinzmann D, Bangert A, Müller AM, von Ungern-Sternberg SN, Emschermann F, Schönberger T, Chatterjee M, Mack AF, Klingel K, Kandolf R, Malesevic M, Borst O, Gawaz M, Langer HF, Katus H, Fischer G, May AE, Kaya Z, Seizer P
PloS one 2015;10(4):e0124606
PloS one 2015;10(4):e0124606
Tumor-Infiltrating Immune Cells Are Associated With Prognosis of Gastric Cancer.
Liu K, Yang K, Wu B, Chen H, Chen X, Chen X, Jiang L, Ye F, He D, Lu Z, Xue L, Zhang W, Li Q, Zhou Z, Mo X, Hu J
Medicine 2015 Sep;94(39):e1631
Medicine 2015 Sep;94(39):e1631
CXCR2-CXCL1 axis is correlated with neutrophil infiltration and predicts a poor prognosis in hepatocellular carcinoma.
Li L, Xu L, Yan J, Zhen ZJ, Ji Y, Liu CQ, Lau WY, Zheng L, Xu J
Journal of experimental & clinical cancer research : CR 2015 Oct 26;34:129
Journal of experimental & clinical cancer research : CR 2015 Oct 26;34:129
Autoimmune encephalitis in humans: how closely does it reflect multiple sclerosis ?
Höftberger R, Leisser M, Bauer J, Lassmann H
Acta neuropathologica communications 2015 Dec 4;3:80
Acta neuropathologica communications 2015 Dec 4;3:80
Harnessing high density lipoproteins to block transforming growth factor beta and to inhibit the growth of liver tumor metastases.
Medina-Echeverz J, Fioravanti J, Díaz-Valdés N, Frank K, Aranda F, Gomar C, Ardaiz N, Dotor J, Umansky V, Prieto J, Berraondo P
PloS one 2014;9(5):e96799
PloS one 2014;9(5):e96799
Comparative characterization of stroma cells and ductal epithelium in chronic pancreatitis and pancreatic ductal adenocarcinoma.
Helm O, Mennrich R, Petrick D, Goebel L, Freitag-Wolf S, Röder C, Kalthoff H, Röcken C, Sipos B, Kabelitz D, Schäfer H, Oberg HH, Wesch D, Sebens S
PloS one 2014;9(5):e94357
PloS one 2014;9(5):e94357
EGFRvIII-specific chimeric antigen receptor T cells migrate to and kill tumor deposits infiltrating the brain parenchyma in an invasive xenograft model of glioblastoma.
Miao H, Choi BD, Suryadevara CM, Sanchez-Perez L, Yang S, De Leon G, Sayour EJ, McLendon R, Herndon JE 2nd, Healy P, Archer GE, Bigner DD, Johnson LA, Sampson JH
PloS one 2014;9(4):e94281
PloS one 2014;9(4):e94281
Regulation of proximal T cell receptor signaling and tolerance induction by deubiquitinase Usp9X.
Naik E, Webster JD, DeVoss J, Liu J, Suriben R, Dixit VM
The Journal of experimental medicine 2014 Sep 22;211(10):1947-55
The Journal of experimental medicine 2014 Sep 22;211(10):1947-55
The oxysterol receptor LXRβ protects against DSS- and TNBS-induced colitis in mice.
Jakobsson T, Vedin LL, Hassan T, Venteclef N, Greco D, D'Amato M, Treuter E, Gustafsson JÅ, Steffensen KR
Mucosal immunology 2014 Nov;7(6):1416-28
Mucosal immunology 2014 Nov;7(6):1416-28
Liquid-based cytologic findings of solitary extramedullary plasmacytoma in thyroid: a case report identified with fine-needle aspiration cytology.
Lee CH, Jung YY, Chung YR, Ryu HS
Diagnostic cytopathology 2014 Nov;42(11):964-9
Diagnostic cytopathology 2014 Nov;42(11):964-9
CD30(+) extranodal natural killer/T-cell lymphoma mimicking phlegmonous myositis: A case report.
Yang YJ, Li YX, Liu YB, Yang M, Liu K
Oncology letters 2014 May;7(5):1419-1421
Oncology letters 2014 May;7(5):1419-1421
Colonic mucosal immune activity in irritable bowel syndrome: comparison with healthy controls and patients with ulcerative colitis.
Ahn JY, Lee KH, Choi CH, Kim JW, Lee HW, Kim JW, Kim MK, Kwon GY, Han S, Kim SE, Kim SM, Chang SK
Digestive diseases and sciences 2014 May;59(5):1001-11
Digestive diseases and sciences 2014 May;59(5):1001-11
Functional validation of a human CAPN5 exome variant by lentiviral transduction into mouse retina.
Wert KJ, Skeie JM, Bassuk AG, Olivier AK, Tsang SH, Mahajan VB
Human molecular genetics 2014 May 15;23(10):2665-77
Human molecular genetics 2014 May 15;23(10):2665-77
Differential expression of BAFF and its receptors in discoid lupus erythematosus patients.
Chong BF, Tseng LC, Kim A, Miller RT, Yancey KB, Hosler GA
Journal of dermatological science 2014 Mar;73(3):216-24
Journal of dermatological science 2014 Mar;73(3):216-24
Novel bispecific antibodies increase γδ T-cell cytotoxicity against pancreatic cancer cells.
Oberg HH, Peipp M, Kellner C, Sebens S, Krause S, Petrick D, Adam-Klages S, Röcken C, Becker T, Vogel I, Weisner D, Freitag-Wolf S, Gramatzki M, Kabelitz D, Wesch D
Cancer research 2014 Mar 1;74(5):1349-60
Cancer research 2014 Mar 1;74(5):1349-60
Mouse models of mantle cell lymphoma, complex changes in gene expression and phenotype of engrafted MCL cells: implications for preclinical research.
Klanova M, Soukup T, Jaksa R, Molinsky J, Lateckova L, Maswabi BC, Prukova D, Brezinova J, Michalova K, Vockova P, Hernandez-Ilizaliturri F, Kulvait V, Zivny J, Vokurka M, Necas E, Trneny M, Klener P
Laboratory investigation; a journal of technical methods and pathology 2014 Jul;94(7):806-17
Laboratory investigation; a journal of technical methods and pathology 2014 Jul;94(7):806-17
Bioactive nanocomposite for chest-wall replacement: Cellular response in a murine model.
Jungraithmayr W, Laube I, Hild N, Stark WJ, Mihic-Probst D, Weder W, Buschmann J
Journal of biomaterials applications 2014 Jul;29(1):36-45
Journal of biomaterials applications 2014 Jul;29(1):36-45
Metastatic growth progression caused by PSGL-1-mediated recruitment of monocytes to metastatic sites.
Hoos A, Protsyuk D, Borsig L
Cancer research 2014 Feb 1;74(3):695-704
Cancer research 2014 Feb 1;74(3):695-704
Multiple sclerosis deep grey matter: the relation between demyelination, neurodegeneration, inflammation and iron.
Haider L, Simeonidou C, Steinberger G, Hametner S, Grigoriadis N, Deretzi G, Kovacs GG, Kutzelnigg A, Lassmann H, Frischer JM
Journal of neurology, neurosurgery, and psychiatry 2014 Dec;85(12):1386-95
Journal of neurology, neurosurgery, and psychiatry 2014 Dec;85(12):1386-95
Epstein-Barr virus-associated adrenal smooth muscle tumors and disseminated diffuse large B-cell lymphoma in a child with common variable immunodeficiency: a case report and review of the literature.
Petrilli G, Lorenzi L, Paracchini R, Ubiali A, Schumacher RF, Cabassa P, Facchetti F
International journal of surgical pathology 2014 Dec;22(8):712-21
International journal of surgical pathology 2014 Dec;22(8):712-21
Expression of indoleamine 2,3-dioxygenase and infiltration of FOXP3+ regulatory T cells are associated with aggressive features of papillary thyroid microcarcinoma.
Ryu HS, Park YS, Park HJ, Chung YR, Yom CK, Ahn SH, Park YJ, Park SH, Park SY
Thyroid : official journal of the American Thyroid Association 2014 Aug;24(8):1232-40
Thyroid : official journal of the American Thyroid Association 2014 Aug;24(8):1232-40
Constitutive expression of murine c-FLIPR causes autoimmunity in aged mice.
Ewald F, Annemann M, Pils MC, Plaza-Sirvent C, Neff F, Erck C, Reinhold D, Schmitz I
Cell death & disease 2014 Apr 10;5(4):e1168
Cell death & disease 2014 Apr 10;5(4):e1168
The chemokine CCL3 promotes experimental liver fibrosis in mice.
Heinrichs D, Berres ML, Nellen A, Fischer P, Scholten D, Trautwein C, Wasmuth HE, Sahin H
PloS one 2013;8(6):e66106
PloS one 2013;8(6):e66106
Immune cells from SR/CR mice induce the regression of established tumors in BALB/c and C57BL/6 mice.
Koch J, Hau J, Pravsgaard Christensen J, Elvang Jensen H, Bagge Hansen M, Rieneck K
PloS one 2013;8(3):e59995
PloS one 2013;8(3):e59995
Occurrence of nodular lymphocyte-predominant hodgkin lymphoma in hermansky-pudlak type 2 syndrome is associated to natural killer and natural killer T cell defects.
Lorenzi L, Tabellini G, Vermi W, Moratto D, Porta F, Notarangelo LD, Patrizi O, Sozzani S, de Saint Basile G, Latour S, Pace D, Lonardi S, Facchetti F, Badolato R, Parolini S
PloS one 2013;8(11):e80131
PloS one 2013;8(11):e80131
Histopathological, immunophenotypic and clinical particularities and evolution of a case of hepatosplenic T-cell lymphoma in transformation to leukemia.
Benedek Lázár E, Köpeczi JB, Tunyogi AB, Kakucs E, Horváth E, Turcu M, Benedek I
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2013;54(4):1135-9
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2013;54(4):1135-9
A histological analysis of gingival condition associated with orthodontic treatment.
Mártha K, Mezei T, Jánosi K
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2013;54(3 Suppl):823-7
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2013;54(3 Suppl):823-7
Ezrin/Radixin/Moesin proteins and flotillins cooperate to promote uropod formation in T cells.
Martinelli S, Chen EJ, Clarke F, Lyck R, Affentranger S, Burkhardt JK, Niggli V
Frontiers in immunology 2013;4:84
Frontiers in immunology 2013;4:84
The p53 Codon 72 Polymorphism Modifies the Cellular Response to Inflammatory Challenge in the Liver.
Leu JI, Murphy ME, George DL
Journal of liver 2013;2(1)
Journal of liver 2013;2(1)
Upregulation of adenosine kinase in Rasmussen encephalitis.
Luan G, Gao Q, Guan Y, Zhai F, Zhou J, Liu C, Chen Y, Yao K, Qi X, Li T
Journal of neuropathology and experimental neurology 2013 Nov;72(11):1000-8
Journal of neuropathology and experimental neurology 2013 Nov;72(11):1000-8
Corelation of lymphocytic infiltrates with the prognosis of recurrent colo-rectal cancer.
Makkai-Popa ST, Luncă S, Dimofte G, Vrânceanu A, Franciug D, Ivanov I, Zugun F, Târcoveanu E, Carasevici E
Chirurgia (Bucharest, Romania : 1990) 2013 Nov-Dec;108(6):859-65
Chirurgia (Bucharest, Romania : 1990) 2013 Nov-Dec;108(6):859-65
Neutralization of ocular surface TNF-α reduces ocular surface and lacrimal gland inflammation induced by in vivo dry eye.
Ji YW, Byun YJ, Choi W, Jeong E, Kim JS, Noh H, Kim ES, Song YJ, Park SK, Lee HK
Investigative ophthalmology & visual science 2013 Nov 15;54(12):7557-66
Investigative ophthalmology & visual science 2013 Nov 15;54(12):7557-66
Humanized mice, a new model to study the influence of drug treatment on neonatal sepsis.
Ernst W, Zimara N, Hanses F, Männel DN, Seelbach-Göbel B, Wege AK
Infection and immunity 2013 May;81(5):1520-31
Infection and immunity 2013 May;81(5):1520-31
Intrastriatal injection of interleukin-1 beta triggers the formation of neuromyelitis optica-like lesions in NMO-IgG seropositive rats.
Kitic M, Hochmeister S, Wimmer I, Bauer J, Misu T, Mader S, Reindl M, Fujihara K, Lassmann H, Bradl M
Acta neuropathologica communications 2013 May 8;1:5
Acta neuropathologica communications 2013 May 8;1:5
Human Immunodeficiency Virus (HIV)-Negative and Human Herpes Virus-8 (HHV-8)-Positive Primary Effusion Lymphoma: A Case Report and Review of the Literature.
Güven Karataş S, Bayrak R, Sahin Balçık O, Yalçın KS, Atıcı E, Akyıldız U, Koşar A
Turkish journal of haematology : official journal of Turkish Society of Haematology 2013 Mar;30(1):67-71
Turkish journal of haematology : official journal of Turkish Society of Haematology 2013 Mar;30(1):67-71
Clinicopathological features of aggressive B-cell lymphomas including B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell and Burkitt lymphomas: a study of 44 patients from Argentina.
Bürgesser MV, Gualco G, Diller A, Natkunam Y, Bacchi CE
Annals of diagnostic pathology 2013 Jun;17(3):250-5
Annals of diagnostic pathology 2013 Jun;17(3):250-5
Disease-specific molecular events in cortical multiple sclerosis lesions.
Fischer MT, Wimmer I, Höftberger R, Gerlach S, Haider L, Zrzavy T, Hametner S, Mahad D, Binder CJ, Krumbholz M, Bauer J, Bradl M, Lassmann H
Brain : a journal of neurology 2013 Jun;136(Pt 6):1799-815
Brain : a journal of neurology 2013 Jun;136(Pt 6):1799-815
Characterization of the inflammatory response to solid cancer metastases in the human brain.
Berghoff AS, Lassmann H, Preusser M, Höftberger R
Clinical & experimental metastasis 2013 Jan;30(1):69-81
Clinical & experimental metastasis 2013 Jan;30(1):69-81
Expression of FOXP3, CD68, and CD20 at diagnosis in the microenvironment of classical Hodgkin lymphoma is predictive of outcome.
Greaves P, Clear A, Coutinho R, Wilson A, Matthews J, Owen A, Shanyinde M, Lister TA, Calaminici M, Gribben JG
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2013 Jan 10;31(2):256-62
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2013 Jan 10;31(2):256-62
Blastic plasmacytoid dendritic cell neoplasm with leukemic presentation: an Italian multicenter study.
Pagano L, Valentini CG, Pulsoni A, Fisogni S, Carluccio P, Mannelli F, Lunghi M, Pica G, Onida F, Cattaneo C, Piccaluga PP, Di Bona E, Todisco E, Musto P, Spadea A, D'Arco A, Pileri S, Leone G, Amadori S, Facchetti F, GIMEMA-ALWP (Gruppo Italiano Malattie EMatologiche dell'Adulto, Acute Leukemia Working Party)
Haematologica 2013 Feb;98(2):239-46
Haematologica 2013 Feb;98(2):239-46
Wiskott-Aldrich syndrome protein-mediated actin dynamics control type-I interferon production in plasmacytoid dendritic cells.
Prete F, Catucci M, Labrada M, Gobessi S, Castiello MC, Bonomi E, Aiuti A, Vermi W, Cancrini C, Metin A, Hambleton S, Bredius R, Notarangelo LD, van der Burg M, Kalinke U, Villa A, Benvenuti F
The Journal of experimental medicine 2013 Feb 11;210(2):355-74
The Journal of experimental medicine 2013 Feb 11;210(2):355-74
Microvascular proliferations in arteriovenous malformations relate to high-flow characteristics, inflammation, and previous therapeutic embolization of the lesion.
Meijer-Jorna LB, van der Loos CM, de Boer OJ, Horrevoets AJG, Mekkes JR, van der Horst CMAM, van der Wal AC
Journal of the American Academy of Dermatology 2013 Apr;68(4):638-646
Journal of the American Academy of Dermatology 2013 Apr;68(4):638-646
Clinicopathology, immunophenotype, T cell receptor gene rearrangement, Epstein-Barr virus status and p53 gene mutation of cutaneous extranodal NK/T-cell lymphoma, nasal-type.
Wang TT, Xu C, Liu SL, Kan B, Ran YP, Liu WP, Li GD, Wang L
Chinese medical journal 2013 Apr;126(7):1281-7
Chinese medical journal 2013 Apr;126(7):1281-7
Alcohol based fixatives provide excellent tissue morphology, protein immunoreactivity and RNA integrity in paraffin embedded tissue specimens.
Milcheva R, Janega P, Celec P, Russev R, Babál P
Acta histochemica 2013 Apr;115(3):279-89
Acta histochemica 2013 Apr;115(3):279-89
Lymphotoxin, but not TNF, is required for prion invasion of lymph nodes.
O'Connor T, Frei N, Sponarova J, Schwarz P, Heikenwalder M, Aguzzi A
PLoS pathogens 2012;8(8):e1002867
PLoS pathogens 2012;8(8):e1002867
Targeting melanoma metastasis and immunosuppression with a new mode of melanoma inhibitory activity (MIA) protein inhibition.
Schmidt J, Riechers A, Stoll R, Amann T, Fink F, Spruss T, Gronwald W, König B, Hellerbrand C, Bosserhoff AK
PloS one 2012;7(5):e37941
PloS one 2012;7(5):e37941
Invariant NKT cells drive hepatic cytokinic microenvironment favoring efficient granuloma formation and early control of Leishmania donovani infection.
Robert-Gangneux F, Drogoul AS, Rostan O, Piquet-Pellorce C, Cayon J, Lisbonne M, Herbelin A, Gascan H, Guiguen C, Samson M, Gangneux JP
PloS one 2012;7(3):e33413
PloS one 2012;7(3):e33413
VR09 cell line: an EBV-positive lymphoblastoid cell line with in vivo characteristics of diffuse large B cell lymphoma of activated B-cell type.
Nichele I, Zamò A, Bertolaso A, Bifari F, Tinelli M, Franchini M, Stradoni R, Aprili F, Pizzolo G, Krampera M
PloS one 2012;7(12):e52811
PloS one 2012;7(12):e52811
Targeting BRAFV600E in an inducible murine model of melanoma.
Hooijkaas AI, Gadiot J, van der Valk M, Mooi WJ, Blank CU
The American journal of pathology 2012 Sep;181(3):785-94
The American journal of pathology 2012 Sep;181(3):785-94
Rats deficient for p53 are susceptible to spontaneous and carcinogen-induced tumorigenesis.
Yan HX, Wu HP, Ashton C, Tong C, Ying QL
Carcinogenesis 2012 Oct;33(10):2001-5
Carcinogenesis 2012 Oct;33(10):2001-5
Congenital cytomegalovirus infection: patterns of fetal brain damage.
Gabrielli L, Bonasoni MP, Santini D, Piccirilli G, Chiereghin A, Petrisli E, Dolcetti R, Guerra B, Piccioli M, Lanari M, Landini MP, Lazzarotto T
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2012 Oct;18(10):E419-27
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2012 Oct;18(10):E419-27
The TNF family member APRIL promotes colorectal tumorigenesis.
Lascano V, Zabalegui LF, Cameron K, Guadagnoli M, Jansen M, Burggraaf M, Versloot M, Rodermond H, van der Loos C, Carvalho-Pinto CE, Kalthoff H, Medema JP, Hahne M
Cell death and differentiation 2012 Nov;19(11):1826-35
Cell death and differentiation 2012 Nov;19(11):1826-35
Endothelial insulin receptor expression in human atherosclerotic plaques: linking micro- and macrovascular disease in diabetes?
Rensing KL, von der Thüsen JH, Weijers EM, Houttuijn Bloemendaal FM, van Lammeren GW, Vink A, van der Wal AC, van Hinsbergh VW, van der Loos CM, Stroes ES, Koolwijk P, Twickler TB
Atherosclerosis 2012 May;222(1):208-15
Atherosclerosis 2012 May;222(1):208-15
The development and fate of follicular helper T cells defined by an IL-21 reporter mouse.
Lüthje K, Kallies A, Shimohakamada Y, Belz GT, Light A, Tarlinton DM, Nutt SL
Nature immunology 2012 May;13(5):491-8
Nature immunology 2012 May;13(5):491-8
Mucosal immune cell numbers and visceral sensitivity in patients with irritable bowel syndrome: is there any relationship?
Braak B, Klooker TK, Wouters MM, Welting O, van der Loos CM, Stanisor OI, van Diest S, van den Wijngaard RM, Boeckxstaens GE
The American journal of gastroenterology 2012 May;107(5):715-26
The American journal of gastroenterology 2012 May;107(5):715-26
Cyclophilin A affects inflammation, virus elimination and myocardial fibrosis in coxsackievirus B3-induced myocarditis.
Seizer P, Klingel K, Sauter M, Westermann D, Ochmann C, Schönberger T, Schleicher R, Stellos K, Schmidt EM, Borst O, Bigalke B, Kandolf R, Langer H, Gawaz M, May AE
Journal of molecular and cellular cardiology 2012 Jul;53(1):6-14
Journal of molecular and cellular cardiology 2012 Jul;53(1):6-14
Chlamydia psittaci-negative ocular adnexal marginal zone B-cell lymphomas have biased VH4-34 immunoglobulin gene expression and proliferate in a distinct inflammatory environment.
van Maldegem F, Wormhoudt TA, Mulder MM, Oud ME, Schilder-Tol E, Musler AR, Aten J, Saeed P, Kersten MJ, Pals ST, van Noesel CJ, Bende RJ
Leukemia 2012 Jul;26(7):1647-53
Leukemia 2012 Jul;26(7):1647-53
Lymphoid tissue damage in HIV-1 infection depletes naïve T cells and limits T cell reconstitution after antiretroviral therapy.
Zeng M, Southern PJ, Reilly CS, Beilman GJ, Chipman JG, Schacker TW, Haase AT
PLoS pathogens 2012 Jan;8(1):e1002437
PLoS pathogens 2012 Jan;8(1):e1002437
Electrospun small-diameter polyurethane vascular grafts: ingrowth and differentiation of vascular-specific host cells.
Bergmeister H, Grasl C, Walter I, Plasenzotti R, Stoiber M, Schreiber C, Losert U, Weigel G, Schima H
Artificial organs 2012 Jan;36(1):54-61
Artificial organs 2012 Jan;36(1):54-61
Folliculocentric B-cell-rich follicular dendritic cells sarcoma: a hitherto unreported morphological variant mimicking lymphoproliferative disorders.
Lorenzi L, Lonardi S, Petrilli G, Tanda F, Bella M, Laurino L, Rossi G, Facchetti F
Human pathology 2012 Feb;43(2):209-15
Human pathology 2012 Feb;43(2):209-15
Tubular lesions predict renal outcome in antineutrophil cytoplasmic antibody-associated glomerulonephritis after rituximab therapy.
Berden AE, Jones RB, Erasmus DD, Walsh M, Noël LH, Ferrario F, Waldherr R, Bruijn JA, Jayne DR, Bajema IM, European Vasculitis Society
Journal of the American Society of Nephrology : JASN 2012 Feb;23(2):313-21
Journal of the American Society of Nephrology : JASN 2012 Feb;23(2):313-21
Leukocyte composition of human breast cancer.
Ruffell B, Au A, Rugo HS, Esserman LJ, Hwang ES, Coussens LM
Proceedings of the National Academy of Sciences of the United States of America 2012 Feb 21;109(8):2796-801
Proceedings of the National Academy of Sciences of the United States of America 2012 Feb 21;109(8):2796-801
BCL10 down-regulation in peripheral T-cell lymphomas.
Rossi M, Agostinelli C, Righi S, Sabattini E, Bacci F, Gazzola A, Pileri SA, Piccaluga PP
Human pathology 2012 Dec;43(12):2266-73
Human pathology 2012 Dec;43(12):2266-73
Bioactive acellular implant induces angiogenesis and adipogenesis and sustained soft tissue restoration in vivo.
Sarkanen JR, Ruusuvuori P, Kuokkanen H, Paavonen T, Ylikomi T
Tissue engineering. Part A 2012 Dec;18(23-24):2568-80
Tissue engineering. Part A 2012 Dec;18(23-24):2568-80
The TGF-β co-receptor endoglin regulates macrophage infiltration and cytokine production in the irradiated mouse kidney.
Scharpfenecker M, Floot B, Russell NS, Stewart FA
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2012 Dec;105(3):313-20
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2012 Dec;105(3):313-20
Th17 cells induce a distinct graft rejection response that does not require IL-17A.
Agorogiannis EI, Regateiro FS, Howie D, Waldmann H, Cobbold SP
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2012 Apr;12(4):835-45
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2012 Apr;12(4):835-45
Expression of B-RAF V600E in type II pneumocytes causes abnormalities in alveolar formation, airspace enlargement and tumor formation in mice.
Zanucco E, Götz R, Potapenko T, Carraretto I, Ceteci S, Ceteci F, Seeger W, Savai R, Rapp UR
PloS one 2011;6(12):e29093
PloS one 2011;6(12):e29093
Intratumoral Immune Responses Can Distinguish New Primary and True Recurrence Types of Ipsilateral Breast Tumor Recurrences (IBTR).
West NR, Panet-Raymond V, Truong PT, Alexander C, Babinszky S, Milne K, Ross LA, Loken S, Watson PH
Breast cancer : basic and clinical research 2011;5:105-15
Breast cancer : basic and clinical research 2011;5:105-15
Extraintestinal Crohn's disease mimicking autoimmune inner ear disease: a histopathological approach.
Dettmer M, Hegemann I, Hegemann SC
Audiology & neuro-otology 2011;16(1):36-40
Audiology & neuro-otology 2011;16(1):36-40
Tumor-infiltrating lymphocytes predict response to anthracycline-based chemotherapy in estrogen receptor-negative breast cancer.
West NR, Milne K, Truong PT, Macpherson N, Nelson BH, Watson PH
Breast cancer research : BCR 2011;13(6):R126
Breast cancer research : BCR 2011;13(6):R126
Forkhead box protein P1 as a downstream target of transforming growth factor-β induces collagen synthesis and correlates with a more stable plaque phenotype.
Bot PT, Grundmann S, Goumans MJ, de Kleijn D, Moll F, de Boer O, van der Wal AC, van Soest A, de Vries JP, van Royen N, Piek JJ, Pasterkamp G, Hoefer IE
Atherosclerosis 2011 Sep;218(1):33-43
Atherosclerosis 2011 Sep;218(1):33-43
Myocardial pathology in pulmonary thromboembolism.
Orde MM, Puranik R, Morrow PL, Duflou J
Heart (British Cardiac Society) 2011 Oct;97(20):1695-9
Heart (British Cardiac Society) 2011 Oct;97(20):1695-9
MART-1 is a reliable melanocytic marker in lichen planus-like keratosis: a study on 70 cases.
Gavino AC, Woods MT, Andea AA
The American Journal of dermatopathology 2011 Oct;33(7):675-80
The American Journal of dermatopathology 2011 Oct;33(7):675-80
Efficient transgene expression from naked DNA delivered into an arterio-venous fistula model for kidney dialysis.
Globerman AS, Chaouat M, Shlomai Z, Galun E, Zeira E, Zamir G
The journal of gene medicine 2011 Nov;13(11):611-21
The journal of gene medicine 2011 Nov;13(11):611-21
Depletion of CD4⁺ T cells abrogates post-peak decline of viremia in SIV-infected rhesus macaques.
Ortiz AM, Klatt NR, Li B, Yi Y, Tabb B, Hao XP, Sternberg L, Lawson B, Carnathan PM, Cramer EM, Engram JC, Little DM, Ryzhova E, Gonzalez-Scarano F, Paiardini M, Ansari AA, Ratcliffe S, Else JG, Brenchley JM, Collman RG, Estes JD, Derdeyn CA, Silvestri G
The Journal of clinical investigation 2011 Nov;121(11):4433-45
The Journal of clinical investigation 2011 Nov;121(11):4433-45
High frequency of development of B cell lymphoproliferation and diffuse large B cell lymphoma in Dbl knock-in mice.
Ognibene M, Barbieri O, Vanni C, Mastracci L, Astigiano S, Emionite L, Salani B, Fedele M, Resaz R, Tenca C, Fais F, Sabatini F, De Santanna A, Altruda F, Varesio L, Hirsch E, Eva A
Journal of molecular medicine (Berlin, Germany) 2011 May;89(5):493-504
Journal of molecular medicine (Berlin, Germany) 2011 May;89(5):493-504
Specific maternal microchimeric T cells targeting fetal antigens in β cells predispose to auto-immune diabetes in the child.
Roy E, Leduc M, Guegan S, Rachdi L, Kluger N, Scharfmann R, Aractingi S, Khosrotehrani K
Journal of autoimmunity 2011 May;36(3-4):253-62
Journal of autoimmunity 2011 May;36(3-4):253-62
Innate and adaptive immunity in amyotrophic lateral sclerosis: evidence of complement activation.
Sta M, Sylva-Steenland RM, Casula M, de Jong JM, Troost D, Aronica E, Baas F
Neurobiology of disease 2011 Jun;42(3):211-20
Neurobiology of disease 2011 Jun;42(3):211-20
Analysis of IL-17(+) cells in facet joints of patients with spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the Th17-mediated adaptive immune response.
Appel H, Maier R, Wu P, Scheer R, Hempfing A, Kayser R, Thiel A, Radbruch A, Loddenkemper C, Sieper J
Arthritis research & therapy 2011 Jun 20;13(3):R95
Arthritis research & therapy 2011 Jun 20;13(3):R95
Distribution of intrahepatic T, NK and CD3(+)CD56(+)NKT cells alters after liver transplantation: Shift from innate to adaptive immunity?
Werner JM, Lang C, Scherer MN, Farkas SA, Geissler EK, Schlitt HJ, Hornung M
Transplant immunology 2011 Jul;25(1):27-33
Transplant immunology 2011 Jul;25(1):27-33
Composite lymphoma in the anterior mediastinum: a case report and review of the literature.
Yu G, Kong L, Qu G, Zhang Q, Wang W, Jiang L
Diagnostic pathology 2011 Jul 6;6:60
Diagnostic pathology 2011 Jul 6;6:60
Identification of carotid 'vulnerable plaque' by contrast-enhanced ultrasonography: correlation with plaque histology, symptoms and cerebral computed tomography.
Faggioli GL, Pini R, Mauro R, Pasquinelli G, Fittipaldi S, Freyrie A, Serra C, Stella A
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 2011 Feb;41(2):238-48
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 2011 Feb;41(2):238-48
The prolactin receptor is expressed in macrophages within human carotid atherosclerotic plaques: a role for prolactin in atherogenesis?
Reuwer AQ, van Eijk M, Houttuijn-Bloemendaal FM, van der Loos CM, Claessen N, Teeling P, Kastelein JJ, Hamann J, Goffin V, von der Thüsen JH, Twickler MT, Aten J
The Journal of endocrinology 2011 Feb;208(2):107-17
The Journal of endocrinology 2011 Feb;208(2):107-17
Diffuse large B-cell lymphoma involving the central nervous system.
Gualco G, Weiss LM, Barber GN, Bacchi CE
International journal of surgical pathology 2011 Feb;19(1):44-50
International journal of surgical pathology 2011 Feb;19(1):44-50
Sun exposure induces rapid immunological changes in skin and peripheral blood in patients with psoriasis.
Søyland E, Heier I, Rodríguez-Gallego C, Mollnes TE, Johansen FE, Holven KB, Halvorsen B, Aukrust P, Jahnsen FL, de la Rosa Carrillo D, Krogstad AL, Nenseter MS
The British journal of dermatology 2011 Feb;164(2):344-55
The British journal of dermatology 2011 Feb;164(2):344-55
Histopathologic-based prognostic factors of colorectal cancers are associated with the state of the local immune reaction.
Mlecnik B, Tosolini M, Kirilovsky A, Berger A, Bindea G, Meatchi T, Bruneval P, Trajanoski Z, Fridman WH, Pagès F, Galon J
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011 Feb 20;29(6):610-8
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011 Feb 20;29(6):610-8
Essential role of E3 ubiquitin ligase activity in Cbl-b-regulated T cell functions.
Paolino M, Thien CB, Gruber T, Hinterleitner R, Baier G, Langdon WY, Penninger JM
Journal of immunology (Baltimore, Md. : 1950) 2011 Feb 15;186(4):2138-47
Journal of immunology (Baltimore, Md. : 1950) 2011 Feb 15;186(4):2138-47
Expression of the embryological morphogen Nodal in stage III/IV melanoma.
Hooijkaas AI, Gadiot J, van Boven H, Blank C
Melanoma research 2011 Dec;21(6):491-501
Melanoma research 2011 Dec;21(6):491-501
Putting the brakes on mammary tumorigenesis: loss of STAT1 predisposes to intraepithelial neoplasias.
Schneckenleithner C, Bago-Horvath Z, Dolznig H, Neugebauer N, Kollmann K, Kolbe T, Decker T, Kerjaschki D, Wagner KU, Müller M, Stoiber D, Sexl V
Oncotarget 2011 Dec;2(12):1043-54
Oncotarget 2011 Dec;2(12):1043-54
Cytomegalovirus infection presenting as isolated inflammatory polyps of the gastrointestinal tract.
Agaimy A, Mudter J, Märkl B, Chetty R
Pathology 2011 Aug;43(5):440-6
Pathology 2011 Aug;43(5):440-6
Study of cellular immune response against Hepatitis E virus (HEV).
Prabhu SB, Gupta P, Durgapal H, Rath S, Gupta SD, Acharya SK, Panda SK
Journal of viral hepatitis 2011 Aug;18(8):587-94
Journal of viral hepatitis 2011 Aug;18(8):587-94
Functional CD47/signal regulatory protein alpha (SIRP(alpha)) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo.
Legrand N, Huntington ND, Nagasawa M, Bakker AQ, Schotte R, Strick-Marchand H, de Geus SJ, Pouw SM, Böhne M, Voordouw A, Weijer K, Di Santo JP, Spits H
Proceedings of the National Academy of Sciences of the United States of America 2011 Aug 9;108(32):13224-9
Proceedings of the National Academy of Sciences of the United States of America 2011 Aug 9;108(32):13224-9
RNA sensor-induced type I IFN prevents diabetes caused by a β cell-tropic virus in mice.
McCartney SA, Vermi W, Lonardi S, Rossini C, Otero K, Calderon B, Gilfillan S, Diamond MS, Unanue ER, Colonna M
The Journal of clinical investigation 2011 Apr;121(4):1497-507
The Journal of clinical investigation 2011 Apr;121(4):1497-507
Primary central nervous system lymphoma: a study of clinicopathological features and trend in western India.
Pasricha S, Gupta A, Gawande J, Trivedi P, Patel D
Indian journal of cancer 2011 Apr-Jun;48(2):199-203
Indian journal of cancer 2011 Apr-Jun;48(2):199-203
Spatial differences in the presence of FOXP3+ and GranzymeB+ T cells between the intra- and extravascular compartments in renal allograft vasculopathy.
de Boer OJ, Teeling P, Jansen M, Ploegmakers H, van der Loos CM, Kummer JA, Florquin S, van der Wal AC
PloS one 2011 Apr 6;6(4):e18656
PloS one 2011 Apr 6;6(4):e18656
Pediatric lymphomas in Brazil.
Gualco G, Klumb CE, Barber GN, Weiss LM, Bacchi CE
Clinics (Sao Paulo, Brazil) 2010;65(12):1267-77
Clinics (Sao Paulo, Brazil) 2010;65(12):1267-77
Primary central nervous system peripheral T-cell lymphoma in a child.
Gualco G, Wludarski S, Hayashi-Silva L, Medeiros Filho P, Veras G, Bacchi CE
Fetal and pediatric pathology 2010;29(4):224-30
Fetal and pediatric pathology 2010;29(4):224-30
T-cell leukemia 1 expression in nodal Epstein-Barr virus-negative diffuse large B-cell lymphoma and primary mediastinal B-cell lymphoma.
Gualco G, Weiss LM, Barber GN, Bacchi CE
Human pathology 2010 Sep;41(9):1238-44
Human pathology 2010 Sep;41(9):1238-44
T cell density and location can influence the prognosis of ovarian cancer.
Al-Attar A, Shehata M, Durrant L, Moseley P, Deen S, Chan S
Pathology oncology research : POR 2010 Sep;16(3):361-70
Pathology oncology research : POR 2010 Sep;16(3):361-70
Permissive environment for B-cell maturation in myositis muscle in the absence of B-cell follicles.
Salajegheh M, Pinkus JL, Amato AA, Morehouse C, Jallal B, Yao Y, Greenberg SA
Muscle & nerve 2010 Oct;42(4):576-83
Muscle & nerve 2010 Oct;42(4):576-83
Demyelination versus remyelination in progressive multiple sclerosis.
Bramow S, Frischer JM, Lassmann H, Koch-Henriksen N, Lucchinetti CF, Sørensen PS, Laursen H
Brain : a journal of neurology 2010 Oct;133(10):2983-98
Brain : a journal of neurology 2010 Oct;133(10):2983-98
CD34+ cells from AML with mutated NPM1 harbor cytoplasmic mutated nucleophosmin and generate leukemia in immunocompromised mice.
Martelli MP, Pettirossi V, Thiede C, Bonifacio E, Mezzasoma F, Cecchini D, Pacini R, Tabarrini A, Ciurnelli R, Gionfriddo I, Manes N, Rossi R, Giunchi L, Oelschlägel U, Brunetti L, Gemei M, Delia M, Specchia G, Liso A, Di Ianni M, Di Raimondo F, Falzetti F, Del Vecchio L, Martelli MF, Falini B
Blood 2010 Nov 11;116(19):3907-22
Blood 2010 Nov 11;116(19):3907-22
Primary plasmacytoma of the cervix in a 21-year-old female patient.
Schor AP, Moraes MP, Bisson FW, Bisson MA, Luiz OM, Bacchi CE
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2010 May;29(3):290-3
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2010 May;29(3):290-3
Interferon gamma-induced human guanylate binding protein 1 inhibits mammary tumor growth in mice.
Lipnik K, Naschberger E, Gonin-Laurent N, Kodajova P, Petznek H, Rungaldier S, Astigiano S, Ferrini S, Stürzl M, Hohenadl C
Molecular medicine (Cambridge, Mass.) 2010 May-Jun;16(5-6):177-87
Molecular medicine (Cambridge, Mass.) 2010 May-Jun;16(5-6):177-87
Host-detrimental role of Esx-1-mediated inflammasome activation in mycobacterial infection.
Carlsson F, Kim J, Dumitru C, Barck KH, Carano RA, Sun M, Diehl L, Brown EJ
PLoS pathogens 2010 May 6;6(5):e1000895
PLoS pathogens 2010 May 6;6(5):e1000895
The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma.
Pechloff K, Holch J, Ferch U, Schweneker M, Brunner K, Kremer M, Sparwasser T, Quintanilla-Martinez L, Zimber-Strobl U, Streubel B, Gewies A, Peschel C, Ruland J
The Journal of experimental medicine 2010 May 10;207(5):1031-44
The Journal of experimental medicine 2010 May 10;207(5):1031-44
Differential expression of interleukin-17 family cytokines in intact and complicated human atherosclerotic plaques.
de Boer OJ, van der Meer JJ, Teeling P, van der Loos CM, Idu MM, van Maldegem F, Aten J, van der Wal AC
The Journal of pathology 2010 Mar;220(4):499-508
The Journal of pathology 2010 Mar;220(4):499-508
Human peripheral lymphoid tissues contain autoimmune regulator-expressing dendritic cells.
Poliani PL, Kisand K, Marrella V, Ravanini M, Notarangelo LD, Villa A, Peterson P, Facchetti F
The American journal of pathology 2010 Mar;176(3):1104-12
The American journal of pathology 2010 Mar;176(3):1104-12
Axonal prion protein is required for peripheral myelin maintenance.
Bremer J, Baumann F, Tiberi C, Wessig C, Fischer H, Schwarz P, Steele AD, Toyka KV, Nave KA, Weis J, Aguzzi A
Nature neuroscience 2010 Mar;13(3):310-8
Nature neuroscience 2010 Mar;13(3):310-8
Myxoid cystitis with "chordoid" lymphocytes: another mimic of invasive urothelial carcinoma.
Hameed O
The American journal of surgical pathology 2010 Jul;34(7):1061-5
The American journal of surgical pathology 2010 Jul;34(7):1061-5
Foxp3+ regulatory T cells and related cytokines differentially expressed in plaque vs. guttate psoriasis vulgaris.
Yan KX, Fang X, Han L, Zhang ZH, Kang KF, Zheng ZZ, Huang Q
The British journal of dermatology 2010 Jul;163(1):48-56
The British journal of dermatology 2010 Jul;163(1):48-56
3D visualization of HIV transfer at the virological synapse between dendritic cells and T cells.
Felts RL, Narayan K, Estes JD, Shi D, Trubey CM, Fu J, Hartnell LM, Ruthel GT, Schneider DK, Nagashima K, Bess JW Jr, Bavari S, Lowekamp BC, Bliss D, Lifson JD, Subramaniam S
Proceedings of the National Academy of Sciences of the United States of America 2010 Jul 27;107(30):13336-41
Proceedings of the National Academy of Sciences of the United States of America 2010 Jul 27;107(30):13336-41
Pseudo-placentational endometrial cysts in a bitch.
Bartel C, Schönkypl S, Walter I
Anatomia, histologia, embryologia 2010 Feb;39(1):74-80
Anatomia, histologia, embryologia 2010 Feb;39(1):74-80
Clinical significance and regulation of the costimulatory molecule B7-H3 in human colorectal carcinoma.
Sun J, Chen LJ, Zhang GB, Jiang JT, Zhu M, Tan Y, Wang HT, Lu BF, Zhang XG
Cancer immunology, immunotherapy : CII 2010 Aug;59(8):1163-71
Cancer immunology, immunotherapy : CII 2010 Aug;59(8):1163-71
Ablation of Dicer from murine Schwann cells increases their proliferation while blocking myelination.
Bremer J, O'Connor T, Tiberi C, Rehrauer H, Weis J, Aguzzi A
PloS one 2010 Aug 27;5(8):e12450
PloS one 2010 Aug 27;5(8):e12450
Biomolecular network reconstruction identifies T-cell homing factors associated with survival in colorectal cancer.
Mlecnik B, Tosolini M, Charoentong P, Kirilovsky A, Bindea G, Berger A, Camus M, Gillard M, Bruneval P, Fridman WH, Pagès F, Trajanoski Z, Galon J
Gastroenterology 2010 Apr;138(4):1429-40
Gastroenterology 2010 Apr;138(4):1429-40
Dendritic cell-mediated-immunization with xenogenic PrP and adenoviral vectors breaks tolerance and prolongs mice survival against experimental scrapie.
Rosset MB, Sacquin A, Lecollinet S, Chaigneau T, Adam M, Crespeau F, Eloit M
PloS one 2009;4(3):e4917
PloS one 2009;4(3):e4917
Cutaneous distribution of plasmacytoid dendritic cells in lupus erythematosus. Selective tropism at the site of epithelial apoptotic damage.
Vermi W, Lonardi S, Morassi M, Rossini C, Tardanico R, Venturini M, Sala R, Tincani A, Poliani PL, Calzavara-Pinton PG, Cerroni L, Santoro A, Facchetti F
Immunobiology 2009;214(9-10):877-86
Immunobiology 2009;214(9-10):877-86
Repetitive immunization enhances the susceptibility of mice to peripherally administered prions.
Bremer J, Heikenwalder M, Haybaeck J, Tiberi C, Krautler NJ, Kurrer MO, Aguzzi A
PloS one 2009 Sep 25;4(9):e7160
PloS one 2009 Sep 25;4(9):e7160
Mice deficient for CD137 ligand are predisposed to develop germinal center-derived B-cell lymphoma.
Middendorp S, Xiao Y, Song JY, Peperzak V, Krijger PH, Jacobs H, Borst J
Blood 2009 Sep 10;114(11):2280-9
Blood 2009 Sep 10;114(11):2280-9
Mammary tumors with diverse immunological phenotypes show differing sensitivity to adoptively transferred CD8+ T cells lacking the Cbl-b gene.
Yang T, Martin ML, Nielsen JS, Milne K, Wall EM, Lin W, Watson PH, Nelson BH
Cancer immunology, immunotherapy : CII 2009 Nov;58(11):1865-75
Cancer immunology, immunotherapy : CII 2009 Nov;58(11):1865-75
Homeostatic proliferation of naïve CD8+ T cells depends on CD62L/L-selectin-mediated homing to peripheral LN.
Schuster K, Gadiot J, Andreesen R, Mackensen A, Gajewski TF, Blank C
European journal of immunology 2009 Nov;39(11):2981-90
European journal of immunology 2009 Nov;39(11):2981-90
Diffuse blastoid B-cell lymphoma: a histologically aggressive variant of t(14;18)-negative follicular lymphoma.
Chiu A, Frizzera G, Mathew S, Hyjek EM, Chadburn A, Tam W, Knowles DM, Orazi A
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2009 Nov;22(11):1507-17
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2009 Nov;22(11):1507-17
CD8+ T-cell clones dominate brain infiltrates in Rasmussen encephalitis and persist in the periphery.
Schwab N, Bien CG, Waschbisch A, Becker A, Vince GH, Dornmair K, Wiendl H
Brain : a journal of neurology 2009 May;132(Pt 5):1236-46
Brain : a journal of neurology 2009 May;132(Pt 5):1236-46
Coordination of intratumoral immune reaction and human colorectal cancer recurrence.
Camus M, Tosolini M, Mlecnik B, Pagès F, Kirilovsky A, Berger A, Costes A, Bindea G, Charoentong P, Bruneval P, Trajanoski Z, Fridman WH, Galon J
Cancer research 2009 Mar 15;69(6):2685-93
Cancer research 2009 Mar 15;69(6):2685-93
Priming of protective T cell responses against virus-induced tumors in mice with human immune system components.
Strowig T, Gurer C, Ploss A, Liu YF, Arrey F, Sashihara J, Koo G, Rice CM, Young JW, Chadburn A, Cohen JI, Münz C
The Journal of experimental medicine 2009 Jun 8;206(6):1423-34
The Journal of experimental medicine 2009 Jun 8;206(6):1423-34
Anti-tumor activity of patient-derived NK cells after cell-based immunotherapy--a case report.
Milani V, Stangl S, Issels R, Gehrmann M, Wagner B, Hube K, Mayr D, Hiddemann W, Molls M, Multhoff G
Journal of translational medicine 2009 Jun 23;7:50
Journal of translational medicine 2009 Jun 23;7:50
Vaccine-specific local T cell reactivity in immunotherapy-associated vitiligo in melanoma patients.
Jacobs JF, Aarntzen EH, Sibelt LA, Blokx WA, Boullart AC, Gerritsen MJ, Hoogerbrugge PM, Figdor CG, Adema GJ, Punt CJ, de Vries IJ
Cancer immunology, immunotherapy : CII 2009 Jan;58(1):145-51
Cancer immunology, immunotherapy : CII 2009 Jan;58(1):145-51
Placental endothelial cells can be productively infected by Parvovirus B19.
Pasquinelli G, Bonvicini F, Foroni L, Salfi N, Gallinella G
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2009 Jan;44(1):33-8
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2009 Jan;44(1):33-8
Primary cutaneous CD4+ small/medium-sized pleomorphic T-cell lymphoma expresses follicular T-cell markers.
Rodríguez Pinilla SM, Roncador G, Rodríguez-Peralto JL, Mollejo M, García JF, Montes-Moreno S, Camacho FI, Ortiz P, Limeres-González MA, Torres A, Campo E, Navarro-Conde P, Piris MA
The American journal of surgical pathology 2009 Jan;33(1):81-90
The American journal of surgical pathology 2009 Jan;33(1):81-90
Composite lymphoma: EBV-positive classic Hodgkin lymphoma and peripheral T-cell lymphoma: a case report.
Gualco G, Chioato L, Van Den Berg A, Weiss LM, Bacchi CE
Applied immunohistochemistry & molecular morphology : AIMM 2009 Jan;17(1):72-6
Applied immunohistochemistry & molecular morphology : AIMM 2009 Jan;17(1):72-6
Intravascular lymphocytosis in acute appendicitis: potential mimicry of chronic lymphocytic leukaemia.
Lee S, Ogilvie RT, Dupre M, Gao ZH
Histopathology 2009 Dec;55(6):660-4
Histopathology 2009 Dec;55(6):660-4
What is your diagnosis? Ascites fluid from an 11-year-old dog with epigastric bulging.
Han JI, Jang HJ, Chang DW, Kim GH, Ahn B, Na KJ
Veterinary clinical pathology 2009 Dec;38(4):541-4
Veterinary clinical pathology 2009 Dec;38(4):541-4
Castration induces autoantibody and T cell responses that correlate with inferior outcomes in an androgen-dependent murine tumor model.
Hahn S, Nesslinger NJ, Drapala RJ, Bowden M, Rennie PS, Pai HH, Ludgate C, Nelson BH
International journal of cancer 2009 Dec 15;125(12):2871-8
International journal of cancer 2009 Dec 15;125(12):2871-8
Psoriasis vs allergic contact dermatitis in palms and soles: a quantitative histologic and immunohistochemical study.
Cesinaro AM, Nannini N, Migaldi M, Pepe P, Maiorana A
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2009 Aug;117(8):629-34
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2009 Aug;117(8):629-34
Regulatory T cells and the PD-L1/PD-1 pathway mediate immune suppression in malignant human brain tumors.
Jacobs JF, Idema AJ, Bol KF, Nierkens S, Grauer OM, Wesseling P, Grotenhuis JA, Hoogerbrugge PM, de Vries IJ, Adema GJ
Neuro-oncology 2009 Aug;11(4):394-402
Neuro-oncology 2009 Aug;11(4):394-402
Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23-Th17 pathway.
Espinosa A, Dardalhon V, Brauner S, Ambrosi A, Higgs R, Quintana FJ, Sjöstrand M, Eloranta ML, Ní Gabhann J, Winqvist O, Sundelin B, Jefferies CA, Rozell B, Kuchroo VK, Wahren-Herlenius M
The Journal of experimental medicine 2009 Aug 3;206(8):1661-71
The Journal of experimental medicine 2009 Aug 3;206(8):1661-71
Gaucher or pseudo-Gaucher? The challenge of several diseases colliding in a pediatric patient.
Cajaiba MM, Reyes-Múgica M
Human pathology 2009 Apr;40(4):594-8
Human pathology 2009 Apr;40(4):594-8
Frequent expression of multiple myeloma 1/interferon regulatory factor 4 in Burkitt lymphoma.
Gualco G, Queiroga EM, Weiss LM, Klumb CE, Harrington WJ Jr, Bacchi CE
Human pathology 2009 Apr;40(4):565-71
Human pathology 2009 Apr;40(4):565-71
Plasmoblastic lymphoma associated with human immunodeficiency virus.
Horváth E, Krenács L, Bagdi E, Pávai Z, Macarie I, Nagy EE, Demian S
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2008;49(3):309-14
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2008;49(3):309-14
Local immune alterations in oral mucosa of the edentulous patients; possible cause of teeth loss?
Zurac S, Girtan M, Lavric L, Petsakos G, Stăniceanu F, Bastian A, Andrei R, Popp C, Laba E
Romanian journal of internal medicine = Revue roumaine de medecine interne 2008;46(3):249-53
Romanian journal of internal medicine = Revue roumaine de medecine interne 2008;46(3):249-53
Oncologic trogocytosis of an original stromal cells induces chemoresistance of ovarian tumours.
Rafii A, Mirshahi P, Poupot M, Faussat AM, Simon A, Ducros E, Mery E, Couderc B, Lis R, Capdet J, Bergalet J, Querleu D, Dagonnet F, Fournié JJ, Marie JP, Pujade-Lauraine E, Favre G, Soria J, Mirshahi M
PloS one 2008;3(12):e3894
PloS one 2008;3(12):e3894
Tumor-infiltrating T cells correlate with NY-ESO-1-specific autoantibodies in ovarian cancer.
Milne K, Barnes RO, Girardin A, Mawer MA, Nesslinger NJ, Ng A, Nielsen JS, Sahota R, Tran E, Webb JR, Wong MQ, Wick DA, Wray A, McMurtrie E, Köbel M, Kalloger SE, Gilks CB, Watson PH, Nelson BH
PloS one 2008;3(10):e3409
PloS one 2008;3(10):e3409
Expression of p63 in anaplastic large cell lymphoma but not in classical Hodgkin's lymphoma.
Gualco G, Weiss LM, Bacchi CE
Human pathology 2008 Oct;39(10):1505-10
Human pathology 2008 Oct;39(10):1505-10
Rituximab-induced changes in hematolymphoid tissues found at autopsy.
Cioc AM, Vanderwerf SM, Peterson BA, Robu VG, Forster CL, Pambuccian SE
American journal of clinical pathology 2008 Oct;130(4):604-12
American journal of clinical pathology 2008 Oct;130(4):604-12
The majority of cutaneous marginal zone B-cell lymphomas expresses class-switched immunoglobulins and develops in a T-helper type 2 inflammatory environment.
van Maldegem F, van Dijk R, Wormhoudt TA, Kluin PM, Willemze R, Cerroni L, van Noesel CJ, Bende RJ
Blood 2008 Oct 15;112(8):3355-61
Blood 2008 Oct 15;112(8):3355-61
Temporal delay of peak T-cell immunity determines Chlamydia pneumoniae pulmonary disease in mice.
Wang C, van Ginkel FW, Kim T, Li D, Li Y, Dennis JC, Kaltenboeck B
Infection and immunity 2008 Nov;76(11):4913-23
Infection and immunity 2008 Nov;76(11):4913-23
Early resolution of acute immune activation and induction of PD-1 in SIV-infected sooty mangabeys distinguishes nonpathogenic from pathogenic infection in rhesus macaques.
Estes JD, Gordon SN, Zeng M, Chahroudi AM, Dunham RM, Staprans SI, Reilly CS, Silvestri G, Haase AT
Journal of immunology (Baltimore, Md. : 1950) 2008 May 15;180(10):6798-807
Journal of immunology (Baltimore, Md. : 1950) 2008 May 15;180(10):6798-807
An inducible caspase 9 safety switch can halt cell therapy-induced autoimmune disease.
de Witte MA, Jorritsma A, Swart E, Straathof KC, de Punder K, Haanen JB, Rooney CM, Schumacher TN
Journal of immunology (Baltimore, Md. : 1950) 2008 May 1;180(9):6365-73
Journal of immunology (Baltimore, Md. : 1950) 2008 May 1;180(9):6365-73
T-cell lymphomas in T-cell-specific Pten-deficient mice originate in the thymus.
Hagenbeek TJ, Spits H
Leukemia 2008 Mar;22(3):608-19
Leukemia 2008 Mar;22(3):608-19
Availability of activated CD4+ T cells dictates the level of viremia in naturally SIV-infected sooty mangabeys.
Klatt NR, Villinger F, Bostik P, Gordon SN, Pereira L, Engram JC, Mayne A, Dunham RM, Lawson B, Ratcliffe SJ, Sodora DL, Else J, Reimann K, Staprans SI, Haase AT, Estes JD, Silvestri G, Ansari AA
The Journal of clinical investigation 2008 Jun;118(6):2039-49
The Journal of clinical investigation 2008 Jun;118(6):2039-49
B lymphocyte autoimmunity in rheumatoid synovitis is independent of ectopic lymphoid neogenesis.
Cantaert T, Kolln J, Timmer T, van der Pouw Kraan TC, Vandooren B, Thurlings RM, Cañete JD, Catrina AI, Out T, Verweij CL, Zhang Y, Tak PP, Baeten D
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 1;181(1):785-94
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 1;181(1):785-94
GVHD after chemotherapy conditioning in allogeneic transplanted mice.
Sadeghi B, Aghdami N, Hassan Z, Forouzanfar M, Rozell B, Abedi-Valugerdi M, Hassan M
Bone marrow transplantation 2008 Dec;42(12):807-18
Bone marrow transplantation 2008 Dec;42(12):807-18
N-Methyl-N-Nitrosourea (MNU): A positive control chemical for p53+/- mouse carcinogenicity studies.
Morton D, Bailey KL, Stout CL, Weaver RJ, White KA, Lorenzen MJ, Ball DJ
Toxicologic pathology 2008 Dec;36(7):926-31
Toxicologic pathology 2008 Dec;36(7):926-31
Burkitt lymphoma in Brazil is characterized by geographically distinct clinicopathologic features.
Queiroga EM, Gualco G, Weiss LM, Dittmer DP, Araujo I, Klumb CE, Harrington WJ Jr, Bacchi CE
American journal of clinical pathology 2008 Dec;130(6):946-56
American journal of clinical pathology 2008 Dec;130(6):946-56
Stimulation of lymphocyte responses by angiotensin II promotes kidney injury in hypertension.
Crowley SD, Frey CW, Gould SK, Griffiths R, Ruiz P, Burchette JL, Howell DN, Makhanova N, Yan M, Kim HS, Tharaux PL, Coffman TM
American journal of physiology. Renal physiology 2008 Aug;295(2):F515-24
American journal of physiology. Renal physiology 2008 Aug;295(2):F515-24
Short-lived infected cells support virus replication in sooty mangabeys naturally infected with simian immunodeficiency virus: implications for AIDS pathogenesis.
Gordon SN, Dunham RM, Engram JC, Estes J, Wang Z, Klatt NR, Paiardini M, Pandrea IV, Apetrei C, Sodora DL, Lee HY, Haase AT, Miller MD, Kaur A, Staprans SI, Perelson AS, Feinberg MB, Silvestri G
Journal of virology 2008 Apr;82(7):3725-35
Journal of virology 2008 Apr;82(7):3725-35
Multiple immunoenzyme staining: methods and visualizations for the observation with spectral imaging.
van der Loos CM
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2008 Apr;56(4):313-28
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2008 Apr;56(4):313-28
Differential responsiveness to immunoablative therapy in refractory rheumatoid arthritis is associated with level and avidity of anti-cyclic citrullinated protein autoantibodies: a case study.
Teng YK, Verburg RJ, Verpoort KN, Diepenhorst GM, Bajema IM, van Tol MJ, Jol-van der Zijde EC, Toes RE, Huizinga TW, van Laar JM
Arthritis research & therapy 2007;9(5):R106
Arthritis research & therapy 2007;9(5):R106
Effect of melatonin and zinc on the immune response in experimental Toxoplasma retinochoroiditis.
Avunduk AM, Avunduk MC, Baltaci AK, Moğulkoç R
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 2007;221(6):421-5
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 2007;221(6):421-5
Immunohistochemical analysis of regulatory T cell markers FOXP3 and GITR on CD4+CD25+ T cells in normal skin and inflammatory dermatoses.
de Boer OJ, van der Loos CM, Teeling P, van der Wal AC, Teunissen MB
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2007 Sep;55(9):891-8
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2007 Sep;55(9):891-8
Graft-versus-host-like disease complicating thymoma: lack of AIRE expression as a cause of non-hereditary autoimmunity?
Offerhaus GJ, Schipper ME, Lazenby AJ, Montgomery E, Morsink FH, Bende RJ, Musler AR, van Lier RA, van Noesel CJ
Immunology letters 2007 Nov 30;114(1):31-7
Immunology letters 2007 Nov 30;114(1):31-7
The contribution of bifunctional SkipDewax pretreatment solution, rabbit monoclonal antibodies, and polymer detection systems in immunohistochemistry.
Wong SC, Chan JK, Lo ES, Chan AK, Wong MC, Chan CM, Lam MY, Chan AT
Archives of pathology & laboratory medicine 2007 Jul;131(7):1047-55
Archives of pathology & laboratory medicine 2007 Jul;131(7):1047-55
Differential Noxa/Mcl-1 balance in peripheral versus lymph node chronic lymphocytic leukemia cells correlates with survival capacity.
Smit LA, Hallaert DY, Spijker R, de Goeij B, Jaspers A, Kater AP, van Oers MH, van Noesel CJ, Eldering E
Blood 2007 Feb 15;109(4):1660-8
Blood 2007 Feb 15;109(4):1660-8
Immunohistochemical analysis as a means to predict responsiveness to rituximab treatment.
Teng YK, Levarht EW, Hashemi M, Bajema IM, Toes RE, Huizinga TW, van Laar JM
Arthritis and rheumatism 2007 Dec;56(12):3909-18
Arthritis and rheumatism 2007 Dec;56(12):3909-18
Clinicopathologic findings in high-grade B-cell lymphomas with typical Burkitt morphologic features but lacking the MYC translocation.
Sevilla DW, Gong JZ, Goodman BK, Buckley PJ, Rosoff P, Gockerman JP, Lagoo AS
American journal of clinical pathology 2007 Dec;128(6):981-91
American journal of clinical pathology 2007 Dec;128(6):981-91
Low numbers of FOXP3 positive regulatory T cells are present in all developmental stages of human atherosclerotic lesions.
de Boer OJ, van der Meer JJ, Teeling P, van der Loos CM, van der Wal AC
PloS one 2007 Aug 22;2(8):e779
PloS one 2007 Aug 22;2(8):e779
Macrophage inhibitory cytokine 1 mediates a p53-dependent protective arrest in S phase in response to starvation for DNA precursors.
Agarwal MK, Hastak K, Jackson MW, Breit SN, Stark GR, Agarwal ML
Proceedings of the National Academy of Sciences of the United States of America 2006 Oct 31;103(44):16278-83
Proceedings of the National Academy of Sciences of the United States of America 2006 Oct 31;103(44):16278-83
Disseminated and sustained HIV infection in CD34+ cord blood cell-transplanted Rag2-/-gamma c-/- mice.
Baenziger S, Tussiwand R, Schlaepfer E, Mazzucchelli L, Heikenwalder M, Kurrer MO, Behnke S, Frey J, Oxenius A, Joller H, Aguzzi A, Manz MG, Speck RF
Proceedings of the National Academy of Sciences of the United States of America 2006 Oct 24;103(43):15951-6
Proceedings of the National Academy of Sciences of the United States of America 2006 Oct 24;103(43):15951-6
Establishment of the MAVER-1 cell line, a model for leukemic and aggressive mantle cell lymphoma.
Zamò A, Ott G, Katzenberger T, Adam P, Parolini C, Scarpa A, Lestani M, Menestrina F, Chilosi M
Haematologica 2006 Jan;91(1):40-7
Haematologica 2006 Jan;91(1):40-7
Chemokine receptors in the rheumatoid synovium: upregulation of CXCR5.
Schmutz C, Hulme A, Burman A, Salmon M, Ashton B, Buckley C, Middleton J
Arthritis research & therapy 2005;7(2):R217-29
Arthritis research & therapy 2005;7(2):R217-29
Intratumoral recombinant human interleukin-12 administration in head and neck squamous cell carcinoma patients modifies locoregional lymph node architecture and induces natural killer cell infiltration in the primary tumor.
van Herpen CM, van der Laak JA, de Vries IJ, van Krieken JH, de Wilde PC, Balvers MG, Adema GJ, De Mulder PH
Clinical cancer research : an official journal of the American Association for Cancer Research 2005 Mar 1;11(5):1899-909
Clinical cancer research : an official journal of the American Association for Cancer Research 2005 Mar 1;11(5):1899-909
Invasive inflammatory pseudotumor of uterine cervix: a case report.
Gücer F, Altaner S, Mülayim N, Yapicier O
Gynecologic oncology 2005 Aug;98(2):325-8
Gynecologic oncology 2005 Aug;98(2):325-8
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- Western blot analysis of CD3E was performed by loading 25 µg of Jurkat (Lane 1), CEM (Lane 2) and mouse spleen (Lane 3) cell lysates onto an SDS polyacrylamide gel. Proteins were transferred to a PVDF membrane and blocked at 4ºC overnight. The membrane was probed with a CD3E monoclonal antibody (Product # MA5-14524) at a dilution of 1:50 overnight at 4°C, washed in TBST, and probed with an HRP-conjugated secondary antibody for 1 hr at room temperature in the dark. Chemiluminescent detection was performed using Pierce ECL Plus Western Blotting Substrate (Product # 32132). Results show a band at approx. 20 kDa.
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- Formalin-fixed, paraffin-embedded human tonsil stained with CD3E (Product # MA5-14524) using peroxidase-conjugate and AEC. Note cell membrane staining of T cells.
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- Flow cytometry analysis of CD3E in Jurkat cells (green) compared to an isotype control (blue). Cells were harvested, adjusted to a concentration of 1-5x10^6 cells/mL, fixed with 2% paraformaldehyde and washed with PBS. Cells were blocked with a 2% solution of BSA-PBS for 30 min at room temperature and incubated with a CD3E monoclonal antibody (Product # MA5-14524) at a dilution of 1:2 for 60 min at room temperature. Cells were then incubated for 40 min at room temperature in the dark using a Dylight 488-conjugated secondary antibody and re-suspended in PBS for FACS analysis.
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- Figure 8. ITK-SYK CD19-Cre mice develop clonal PTCLs. (A) ITK-SYK CD19-Cre mice succumb to disease. Kaplan-Meier curve of ITK-SYK CD19-Cre ( n = 18) and control (CD19-Cre) mice ( n = 10). (B) Splenomegaly in ITK-SYK CD19-Cre mice. Representative spleens from 50-wk-old control and ITK-SYK CD19-Cre mice are shown (in centimeters). (C) Solid organ infiltration with abnormally proliferating T cells in ITK-SYK CD19-Cre mice. H&E staining and immunohistochemistry with anti-CD3 and anti-Ki-67 antibodies were performed on liver (LIV) and lung (LNG) sections. Bars, 1 mm. Data representative of six diseased ITK-SYK CD19-Cre mice are shown. (D) Bone marrow (BM) or spleen (SPL) cell suspensions of 50-wk-old control and ITK-SYK CD19-Cre mice were stained against TCR-beta. The frequency of eGFP + T cells in a representative ITK-SYK CD19-Cre mouse is indicated. (E) Expanded T cells in ITK-SYK CD19-Cre mice display an activated phenotype. CD44 and CD62L surface expression on affected T cells or controls was assessed using FACS. One representative example of CD4 + T cells is shown. (F) Spleen cells from diseased ITK-SYK CD19-Cre mice ( n = 16) were stained against CD4 and CD8. Examples of preferential CD4 + T cell (Type I) or CD8 + T cell (Type II) expansions are shown. (G) T cell populations in ITK-SYK CD19-Cre mice are clonal. Single cell suspensions from spleens of individual mice were stained with antibodies against CD4, CD8, and a panel of antibodies against TCR-Vbeta chains (see Materia
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- Figure 2 Histological and biochemical analysis of mice lacking Dicer in Schwann cells. ( A-C ) Longitudinal sections of sciatic nerves from 22-day old Dicer fl/fl Dhh-Cre + and control Dicer wt/fl Dhh-Cre + littermates stained with haematoxylin and eosin (HE) or decorated with S100, MIB1, CD3, or CD68 antibody. At least four nerves were analyzed per genotype. Scale bars = 50 um. S100 positivity indicates Schwann cell development progresses at least up to the stage of immature Schwann cells ( A ). Increased proliferation in Dicer mutant nerves, as indicated by mitotic events (black arrows in A ) and increased percentage of positive nuclei in MIB1 immunohistochemistry ( B ). Quantification of MIB1-positive nuclei shows a significantly higher percentage of proliferating cells in Dicer fl/fl Dhh-Cre + compared to Dicer wt/fl Dhh-Cre + littermate nerves. Error bars indicate standard deviation, p = 0.0003, p value was determined using unpaired two-tailed student's t-test ( B ). Few CD3-positive T cells and an increased percentage of CD68-positive macrophages infiltrated the nerves of Dicer fl/fl Dhh-Cre + mice ( C ). Biochemical analysis of signal transduction pathways and myelin components by Western blot ( D ). Compared to control Dicer wt/fl Dhh-Cre + littermates, phospho-Akt and phospho-Erk were significantly increased in sciatic nerves of 18-day old mice lacking Dicer in Schwann cells, while total Akt and Erk protein levels were unchanged compared to controls, and NFkappaB was
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- Figure 5 Immunohistochemical staining for F4/80 and CD3e in thyroid glands from PPFPThy;PtenThy-/- and PtenThy-/- mice fed pioglitazone or control diet
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- Fig. 6 AZD8931 increases CD8 + T cell content in B4B8 tumors and therapeutic activity is diminished in immune-deficient mice. a B4B8 tumors treated with diluent or AZD8931 (50 mg/kg) for 3 (control, n = 1-2; treated, n = 2), 7 (control, n = 4; treated, n = 4), or 14 (control, n = 2; treated, n = 2) days were formalin fixed, paraffin embedded and submitted to immunofluorescence staining for the T cell marker CD3e with CD4 or CD8alpha. Five ROIs per tumor were randomly selected (accounting for > 70% of the section area). Two independent observers quantified each field of view for the number of positively stained cells per field and the average of the two independent observations and SD are reported. b Representative immunofluorescence images of CD3e + (green), CD8alpha + (red) and DAPI stained B4B8 tumors treated with diluent or AZD8931 (50 mg/kg). c B4B8 tumors were implanted in nu/nu mice or syngeneic BALB/c mice and treated with AZD8931 (50 mg/kg). The percent change in tumor volume of individual tumors after 17 days of treatment with AZD8931 in BALB/c and nu/nu mice is presented as a waterfall plot
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- Fig. 7 Immune cell alterations associated with cetuximab treatment in HNSCC patients. a 22 matched pairs (15 pairs were from non-responders and 7 pairs were from responders) of pre-treatment biopsies and on-treatment (cetuximab) specimens were obtained as FFPE sections on glass slides. Representative images of Vectra 3.0 staining of patient tumors before and following 3-4 weeks of cetuximab treatment. b InForm analysis of immune cell content in primary HNSCC pre- and post-cetuximab treatment. Each data point is the mean of 5-15 distinct regions of interest within each tumor section and the resulting data were submitted to a paired T test
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- Figure 3 Immunohistochemical examination of the mice brains ( A ) Brains of normal mice. ( B ) Brains of EAE mice. ( C ) Brains of IgG-treated mice. ( D ) Brains of EAE mice prophylactically treated with Herceptin. ( E ) Brains of EAE mice therapeutically treated with Herceptin. Both 40X and 400 X magnifications are shown. Rectangles (40 X) show the part of the brains that were enlarged (400 X). H&E staining shows the inflammation determined by arrows. Infiltration of CD3 + cells (anti-CD3 staining) is also demonstrated by black arrows. Similarly, high demyelination is detected by Luxol Fast Blue staining (black arrows).
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- Figure 6. Combination of oncolytic IAV infection and B7-H3 ICI application leads to tumor foci destruction and increased lung- and tumor-infiltration with T lymphocytes Raf-BxB mice were intranasally infected with IAV or solvent control (Mock) and received injections of monoclonal alpha-B7-H3 antibodies or the respective IgG ctrl as indicated in Figure 4A. Sequential paraffin lung tissue sections were stained for human Raf-BxB representing oncogene expressing tumor foci (A) or CD3epsilon + indicating T lymphocyte lung infiltration (B) and counterstained with hematoxylin. Merge pictures of one lung lobe and respective detail pictures of higher magnification of one representative mouse per group are shown. Bars represent 1000 um (merge pictures) or 100 um (close up pictures). (C) For absolute quantification of tumor tissue area, three different sections of each mouse lung stained by IHC for hRAf-BxB were quantified from 5 mice per group. The area of the hRaf-BxB-positive tumor foci was quantified and expressed in relation to the total section area of each lung lobe. Means of three quantified layers per mouse are indicate as one individual entry. n-fold tumor area normalized to the control group (Mock/IgG ctrl) are presented.
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- Figure 2 Treg-specific AMPKalpha1 deficient mice show increased antitumor immunity (A) Representative immunofluorescence staining images of CD3e, CD4, and CD8a in tumor sections from AMPKalpha1 Treg+/+ and AMPKalpha1 Treg-/- mice. Scale bar: 50 mum. (B) Cell numbers of CD3 + , CD4 + , and CD8 + T cells per 40x field in tumor sections from AMPKalpha1 Treg+/+ and AMPKalpha1 Treg-/- mice (n = 5 in each group; data are presented as individual values and mean +- SD and analyzed by Student's t test). Five or more fields per tumor were quantified. (C) Numbers of CD45 + (n = 6), CD3 + (n = 6), CD4 + (n = 6), and CD8 + (n = 5) T cells per 1 x 10 6 tumor cells from day-13 tumor tissues of AMPKalpha1 Treg+/+ and AMPKalpha1 Treg-/- mice measured by flow cytometry (data are presented as individual values and mean +- SD and analyzed by Student's t test). (D) Proportions of CD45 + (n = 6), CD3 + (n = 6), CD4 + (n = 6), and CD8 + (n = 5) T cells in day-13 tumor tissues of AMPKalpha1 Treg+/+ and AMPKalpha1 Treg-/- mice analyzed by flow cytometry (data are presented as individual values and mean +- SD and analyzed by Student's t test). (E) Representative FACS images of IFN-gamma-producing CD8 + cells from day-13 tumor tissues of AMPKalpha1 Treg+/+ and AMPKalpha1 Treg-/- mice. (F) Frequency and numbers of IFN-gamma-producing CD8 + cells per 1x10 6 tumor cells from tumor tissues of AMPKalpha1 Treg+/+ and AMPKalpha1 Treg -/- mice (n = 6 in each group; data are presented as individual values and m
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- Fig. 4 Neutrophils co-localise with apoptotic tumour cells and tumour-associated macrophages in CRC pseudolumina. A Flow cytometric analysis of dissociated CRC tissues and matched normal mucosae of treatment-naive CRC patients. For gating strategy, see Fig. S7A . Graphs present median and 95% CI (%CD66b+ cells, n = 15) or mean +- SD (surface marker MFIs, n = 10-12). * P < 0.05, ** P < 0.01, ns not significant, as calculated by Wilcoxon signed-rank test (%CD66b+ cells) or two-tailed paired t -tests (surface marker MFIs). B Representative CD66b immunohistochemistry (IHC) of a CRC tissue. Red and black arrows indicate stromal and intraluminal neutrophils, respectively, while dotted lines illustrate CRC pseudolumina. Scale bars, 100 um. C , D Consecutive IHC sections of representative CRC specimens stained for M30, cleaved caspase-3 and CD66b ( C upper panel), CD3, CD68 and CD66b ( C lower panel) and IL-8 and CD66b ( D ). Arrows indicate positive staining in CRC pseudolumina. Scale bars, 100 um. E Quantification of cleaved caspase-3-expressing, M30-expressing, IL-8-expressing, CD66b-expressing, CD68-expressing and CD3-expressing CRC pseudolumina in IHC sections of 35 CRC patients. Patients with at least 20 IHC-positive pseudolumina/cm 2 tissue area were considered positive in the presented Venn diagrams. F CD66b and M30 immunofluorescence staining of a CRC pseudolumen. Arrows indicate close contact between CD66b-positive neutrophils and M30-positive apoptotic tumour cells. Images
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- Figure 6. Early Antibody Responses to RV in the Nose Are Cross-Reactive, Limited to IgG, and Coincide with Infiltrating Dual-Specific B Cells (A) Immunohistochemistry analysis of nasal tissue analyzed for CD19 (green), CD3 (white), RV (red), and DNA (blue). Panels on the right show tissue from an uninfected subject (top) and from an infected subject at inferior turbinate (IT), middle turbinate (MT), and nasopharyngeal (NP) sites. Left panels show corresponding negative controls (Ctrl) prepared without primary antibodies. Data are representative of five subjects infected with RV-A16. (B) Cell counts in nasal biopsies from infected subjects after RV-A16 challenge and in uninfected (Un) controls (five per group). Specimens from uninfected subjects were available for a single nasal site only. Averages for each subject were calculated from four image locations within each biopsy. (C) Scatter plots of B cells isolated from nasal tissue (inferior turbinate) from a subject infected with RV-A16 at day 4. Memory B cells (CD19+IgD-) in the nose (black) are overlaid on memory B cells (gray) from the blood of a healthy control for comparison. Representative of three infected subjects. (D) Longitudinal analysis of antibody isotypes specific for homotypic or heterotypic virus (depending on infecting strain) in nasal washes during RV infection (subjects infected with RV-A16 and RV-A39 = 13 and 12, respectively; n = 25 for all time points). Significance was determined by Mann Whitney ranked-s