CABT-BL4389

antibody from Creative Diagnostics

Targeting: CLDN7 CEPTRL2, CPETRL2, Hs.84359

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

CABT-BL4389

Provider

Creative Diagnostics

Product name

Anti-CLDN7 (C-terminal) polyclonal antibody

Antibody type

Polyclonal

Description

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed constitutively in the mammary epithelium throughout development, and might be involved in vesicle trafficking to the basolateral membrane. It is essential for NaCl homeostasis in distal nephrons. The knockout mice lacking this gene showed severe salt wasting, chronic dehydration, and growth retardation, and died within 12 days after birth. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010]

Reactivity

Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Storage

Lyophilized product, 5 years at 2 - 8°C