Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- A03851 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-Claudin 7 (Ab-210) CLDN7 Antibody
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for CLAUDIN 7/CLDN7 detection. Host: Rabbit.Size: 100μl. Tested applications: IHC. Reactive species: Human. CLAUDIN 7/CLDN7 information: Molecular Weight: 22418 MW; Subcellular Localization: Cell membrane; Multi-pass membrane protein. Lateral cell membrane. Cell junction, tight junction. Co- localizes with EPCAM at the lateral cell membrane and tight junction; Tissue Specificity: Expressed in kidney, lung and prostate. Isoform 1 seems to be predominant, except in some normal prostate samples, where isoform 2 is the major form. Down-regulated in breast cancers, including ductal carcinoma in situ (DCIS), lobular carcinoma in situ (LCIS) and invasive ductal carcinoma (IDC) (at protein level), as well as in several cancer cell lines. Loss of expression correlates with histological grade, occurring predominantly in high-grade lesions.
- Reactivity
- Human, Rat
- Host
- Rabbit
- Vial size
- 100μl
- Concentration
- 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
- Storage
- Store at -20°C for one year, at 4°C for one month. We suggest the antibody be aliquoted into small vials and stored frozen at -20°C upon receiving. Avoid repeated freezing and thawing.
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Supportive validation
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- Boster Biological Technology (provider)
- Main image
- Experimental details
- Western blot analysis of extracts from 3T3 cells (Lane 2), using Claudin 7 (Ab-210) antiobdy A03851. The lane on the left is treated with synthesized peptide.
- Additional image