APR02984G

antibody from Leading Biology

Targeting: NLRX1 CLR11.3, NOD9

Western blot

Immunohistochemistry

Antibody data

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Validation data

Product number: APR02984G - Provider product page
Provider: Leading Biology
Product name: NLRX1 Antibody (aa580-630)
Antibody type: Polyclonal
Description: Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (PubMed:18200010). Has no inhibitory function on NF- Kappa-B and type 1 interferon signaling pathways, but enhances NF- Kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species (PubMed:18219313).
Reactivity: Human, Mouse, Rat, Horse, Simian
Host: Rabbit
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

NLRX1 protein structure - APR02984G shown in red.