15903-1-AP

antibody from Proteintech Group

Targeting: RAB11A YL8

Provider product page for 15903-1-AP

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Immunocytochemistry

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Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [48]
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Western blot [1]

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Product number: 15903-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#15903-1-AP, RRID:AB_2173458
Product name: RAB11A/B antibody
Antibody type: Polyclonal
Description: KD/KO validated RAB11A/B antibody (Cat. #15903-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

RAB11A protein structure - 15903-1-AP shown in red.

Submitted references Amphotericin B promotes respiratory viral entry by enhancing late endosomal maturation and fusion via glucocerebrosidase-mediated ceramide remodeling.

He D, Zuo W, Xiang Z, Zhao J, Tong W, Li H, Fang Q, Li X, Zhang Y, Zheng Y, Zhuo X, Pu D, Huang Y, Yuan Y, Wang W, Lu Y, Luo M, Wang P, Wang Z, Cao B
Nature communications 2026 Mar 9;17(1)

SREBP2-RAB11A-ZDHHC20 axis orchestrates FGFR3 palmitoylation and membrane retention to drive bladder cancer progression.

Zhang WW, Qu HR, Du XS, Sun SJ, Chen PR, Deng ZH, Pan Q, Luo FL, Wu HY, Song C, Liu M
Cellular oncology (Dordrecht, Netherlands) 2026 Jan 26;49(1):30

Staphylococcus aureus escapes endosomes and autophagosomes via α-hemolysin.

Xu H, Qi C, Qu C, Lou J, Wang X, Zhang H, Liu J, Liu Y
International immunopharmacology 2026 Feb 1;170:116072

Improved CAR internalization and recycling through transmembrane domain optimization reduces CAR-T cytokine release and exhaustion.

Xie S, Long J, Wang R, Xiang R, Xian H, Wang Y, Dou W, Zhang W, Li D, Kang T, Chen Z, Zhao C, Xu Z, Liu H
Frontiers in immunology 2025;16:1531344

USP47 Regulates Excitatory Synaptic Plasticity and Modulates Seizures in Murine Models by Blocking Ubiquitinated AMPAR Degradation.

Yang J, Zhang H, Wang Y, Luo Y, Zheng W, Liu Y, Jiang Q, Deng J, Liu Q, Zhang P, Huang H, Yu C, Xu Z, Chen Y
Neuroscience bulletin 2025 Oct;41(10):1805-1823

Concentration-dependent formation of intersegment interactions in the viral inclusions of influenza A virus infected cells.

Takizawa N, Higashi K, Kawaguchi RK, Gotoh Y, Hayashi T, Kurokawa K
iScience 2025 Oct 17;28(10):113606

Alterations in PD-L1 succinylation shape anti-tumor immune responses in melanoma.

Liang L, Kuang X, He Y, Zhu L, Lau P, Li X, Luo D, Gong L, Zhou W, Zhang F, Liang X, Li Z, Hu B, Liu D, Ding T, Li H, Zhao S, Su J, Hung MC, Liu J, Liu H, Chen X
Nature genetics 2025 Mar;57(3):680-693

Cholesterol-dependent Nsp5-endosomes co-trafficking to lysosomes facilitates porcine reproductive and respiratory syndrome virus replication by activating autophagy.

Dong H, Pei Q, Ren J, Zhang Y, Wei X, Shen A, Lu Y, Zhang Z, Du Y, Zhuang G, Zhang A, Duan H
Veterinary microbiology 2025 Jun;305:110507

The prognostic and immune significance of Rab11A in pan-cancer and its function and mechanism underlying estrogen receptor targeting in breast cancer.

Li Y, Ding B, Wei M, Yang X, Fu R, Liu Y, Zhu L, Ding Y, Zhang W, Zhang G, Zhang S, Bu Y, He J, Deng J, Bao X, Hao J, Ma L
Asia-Pacific journal of clinical oncology 2025 Feb;21(1):12-30

The imprinted Igf2-Igf2r axis is critical for exosome biogenesis during the early development of bovine placenta.

Zheng K, Xiao L, Yuan N, Sheng X, Qi X, Wang Y, Chen C, Guo K, Yang L, Liu B, Wang X
The Journal of reproduction and development 2025 Feb 5;71(1):41-48

TBC1D20 coordinates vesicle transport and actin remodeling to regulate ciliogenesis.

Zhai D, Li L, Wang D, Wang W, Zhao S, Wang X, Chen C, Zhu Z, Bu W, Yang M, Yin H, Shan Y, Zhao H, Westlake CJ, Lu Q, Zhou J
The Journal of cell biology 2025 Apr 4;224(4)

Peptides targeting RAB11A-FIP2 complex inhibit HPIV3, RSV, and IAV replication as broad-spectrum antivirals.

Jiang Y, Zhao Y, Deng J, Wu X, Li J, Guo D, Xu K, Qin Y, Chen M
Cell & bioscience 2025 Apr 21;15(1):50

Caveolin Regulates the Transport Mechanism of the Walnut-Derived Peptide EVSGPGYSPN to Penetrate the Blood-Brain Barrier.

Li Z, Dang Q, Liu C, Liu Y, Wang C, Zhao F, Wang Q, Min W
Journal of agricultural and food chemistry 2024 Sep 11;72(36):19786-19799

TMED2 promotes glioma tumorigenesis by being involved in EGFR recycling transport.

Sun C, Zhang Y, Wang Z, Chen J, Zhang J, Gu Y
International journal of biological macromolecules 2024 Mar;262(Pt 2):130055

Staphylococcus aureus promotes its intracellular survival by inhibiting Rab11-Rab11FIP4-mediated vesicle trafficking.

Xu H, Wang X, Zhang Z, Hu J, Yu Y, Wang J, Liu Y, Liu J
Veterinary microbiology 2024 Jun;293:110091

Molecular Mechanisms of Intracellular Delivery of Nanoparticles Monitored by an Enzyme-Induced Proximity Labeling.

Ren J, Zhang Z, Geng S, Cheng Y, Han H, Fan Z, Dai W, Zhang H, Wang X, Zhang Q, He B
Nano-micro letters 2024 Feb 1;16(1):103

CREG1 promotes bovine placental trophoblast cells exosome release by targeting IGF2R and participates in regulating organoid differentiation via exosomes transport.

Yuan N, Xiao L, Chen J, Liu B, Ren S, Sheng X, Qi X, Wang Y, Chen C, Guo K, Yang X, Yang L, Wang X
International journal of biological macromolecules 2024 Aug;274(Pt 1):133298

JMJD5 inhibits lung cancer progression by facilitating EGFR proteasomal degradation.

Shen J, Liu G, Qi H, Xiang X, Shao J
Cell death & disease 2023 Oct 9;14(10):657

Bile acids-mediated intracellular cholesterol transport promotes intestinal cholesterol absorption and NPC1L1 recycling.

Xiao J, Dong LW, Liu S, Meng FH, Xie C, Lu XY, Zhang WJ, Luo J, Song BL
Nature communications 2023 Oct 13;14(1):6469

ATG9A regulates the dissociation of recycling endosomes from microtubules to form liquid influenza A virus inclusions.

Vale-Costa S, Etibor TA, Brás D, Sousa AL, Ferreira M, Martins GG, Mello VH, Amorim MJ
PLoS biology 2023 Nov;21(11):e3002290

KIF13B mediates VEGFR2 recycling to modulate vascular permeability.

Cho HD, Nhàn NTT, Zhou C, Tu K, Nguyen T, Sarich NA, Yamada KH
Cellular and molecular life sciences : CMLS 2023 Mar 16;80(4):91

Loss of the batten disease protein CLN3 leads to mis-trafficking of M6PR and defective autophagic-lysosomal reformation.

Calcagni' A, Staiano L, Zampelli N, Minopoli N, Herz NJ, Di Tullio G, Huynh T, Monfregola J, Esposito A, Cirillo C, Bajic A, Zahabiyon M, Curnock R, Polishchuk E, Parkitny L, Medina DL, Pastore N, Cullen PJ, Parenti G, De Matteis MA, Grumati P, Ballabio A
Nature communications 2023 Jul 3;14(1):3911

LRBA signalosomes activate vasopressin-induced AQP2 trafficking at recycling endosomes.

Yanagawa H, Hara Y, Ando F, Suzuki S, Fujiki T, Oikawa D, Yui N, Mandai S, Mori Y, Susa K, Mori T, Sohara E, Tokunaga F, Uchida S
The Journal of physiology 2023 Dec;601(23):5437-5451

Defining basic rules for hardening influenza A virus liquid condensates.

Etibor TA, Vale-Costa S, Sridharan S, Brás D, Becher I, Mello VH, Ferreira F, Alenquer M, Savitski MM, Amorim MJ
eLife 2023 Apr 4;12

Pharmacological suppression of Nedd4-2 rescues the reduction of Kv11.1 channels in pathological cardiac hypertrophy.

Zhang H, Fu T, Sun J, Zou S, Qiu S, Zhang J, Su S, Shi C, Li DP, Xu Y
Frontiers in pharmacology 2022;13:942769

PI4P and BLOC-1 remodel endosomal membranes into tubules.

Jani RA, Di Cicco A, Keren-Kaplan T, Vale-Costa S, Hamaoui D, Hurbain I, Tsai FC, Di Marco M, Macé AS, Zhu Y, Amorim MJ, Bassereau P, Bonifacino JS, Subtil A, Marks MS, Lévy D, Raposo G, Delevoye C
The Journal of cell biology 2022 Nov 7;221(11)

TWIST1 interacts with β/δ-catenins during neural tube development and regulates fate transition in cranial neural crest cells.

Bertol JW, Johnston S, Ahmed R, Xie VK, Hubka KM, Cruz L, Nitschke L, Stetsiv M, Goering JP, Nistor P, Lowell S, Hoskens H, Claes P, Weinberg SM, Saadi I, Farach-Carson MC, Fakhouri WD
Development (Cambridge, England) 2022 Aug 1;149(15)

Porcine Circovirus Type 3 Enters Into PK15 Cells Through Clathrin- and Dynamin-2-Mediated Endocytosis in a Rab5/Rab7 and pH-Dependent Fashion.

Shi R, Hou L, Wei L, Quan R, Zhou B, Jiang H, Wang J, Zhu S, Song J, Wang D, Liu J
Frontiers in microbiology 2021;12:636307

Endocytic recycling as cellular trafficking fate of simvastatin-loaded discoidal reconstituted high-density lipoprotein to coordinate cholesterol efflux and drug influx.

Qi Z, Jiang C, Gao H, Wang Y, Zhang Q, Zhang W, Liu J
Nanomedicine : nanotechnology, biology, and medicine 2021 Feb;32:102323

Endosomal recycling tubule scission and integrin recycling involve the membrane curvature-supporting protein LITAF.

Wunderley L, Zhang L, Yarwood R, Qin W, Lowe M, Woodman P
Journal of cell science 2021 Aug 1;134(15)

Rab11a Is Overexpressed in Gastric Cancer and Regulates FAK/AKT Signaling.

Du J, Fu L, Hao J, Lin X, Dong Q
Journal of oncology 2020;2020:3494396

ANXA6 suppresses the tumorigenesis of cervical cancer through autophagy induction.

Sun X, Shu Y, Xu M, Jiang J, Wang L, Wang J, Huang D, Zhang J
Clinical and translational medicine 2020 Oct;10(6):e208

ARF6-Rac1 signaling-mediated neurite outgrowth is potentiated by the neuronal adaptor FE65 through orchestrating ARF6 and ELMO1.

Chan WWR, Li W, Chang RCC, Lau KF
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16397-16413

Zika virus: mapping and reprogramming the entry.

Owczarek K, Chykunova Y, Jassoy C, Maksym B, Rajfur Z, Pyrc K
Cell communication and signaling : CCS 2019 May 3;17(1):41

Lnc-SNHG1 Activates the TGFBR2/SMAD3 and RAB11A/Wnt/β-Catenin Pathway by Sponging MiR-302/372/373/520 in Invasive Pituitary Tumors.

Wang H, Wang G, Gao Y, Zhao C, Li X, Zhang F, Jiang C, Wu B
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(3):1291-1303

The concerted amyloid-beta clearance of LRP1 and ABCB1/P-gp across the blood-brain barrier is linked by PICALM.

Storck SE, Hartz AMS, Bernard J, Wolf A, Kachlmeier A, Mahringer A, Weggen S, Pahnke J, Pietrzik CU
Brain, behavior, and immunity 2018 Oct;73:21-33

Long noncoding RNA AFAP1-AS1 acts as a competing endogenous RNA of miR-423-5p to facilitate nasopharyngeal carcinoma metastasis through regulating the Rho/Rac pathway.

Lian Y, Xiong F, Yang L, Bo H, Gong Z, Wang Y, Wei F, Tang Y, Li X, Liao Q, Wang H, Zhou M, Xiang B, Wu X, Li Y, Li X, Chen X, Li G, Guo C, Zeng Z, Xiong W
Journal of experimental & clinical cancer research : CR 2018 Oct 16;37(1):253

Canine respiratory coronavirus employs caveolin-1-mediated pathway for internalization to HRT-18G cells.

Szczepanski A, Owczarek K, Milewska A, Baster Z, Rajfur Z, Mitchell JA, Pyrc K
Veterinary research 2018 Jul 3;49(1):55

Rab11 Functions as an Oncoprotein via Nuclear Factor kappa B (NF-κB) Signaling Pathway in Human Bladder Carcinoma.

Gong X, Liu J, Zhang X, Dong F, Liu Y, Wang P
Medical science monitor : international medical journal of experimental and clinical research 2018 Jul 22;24:5093-5101

Piccolo mediates EGFR signaling and acts as a prognostic biomarker in esophageal squamous cell carcinoma.

Zhang W, Hong R, Xue L, Ou Y, Liu X, Zhao Z, Xiao W, Dong D, Dong L, Fu M, Ma L, Lu N, Chen H, Song Y, Zhan Q
Oncogene 2017 Jul 6;36(27):3890-3902

Mutations in the Transmembrane Domain and Cytoplasmic Tail of Hendra Virus Fusion Protein Disrupt Virus-Like-Particle Assembly.

Cifuentes-Muñoz N, Sun W, Ray G, Schmitt PT, Webb S, Gibson K, Dutch RE, Schmitt AP
Journal of virology 2017 Jul 15;91(14)

Rab11a promotes proliferation and invasion through regulation of YAP in non-small cell lung cancer.

Dong Q, Fu L, Zhao Y, Du Y, Li Q, Qiu X, Wang E
Oncotarget 2017 Apr 25;8(17):27800-27811

Rab11a sustains GSK3β/Wnt/β-catenin signaling to enhance cancer progression in pancreatic cancer.

Yu L, Li X, Li H, Chen H, Liu H
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Oct;37(10):13821-13829

AFAP1-AS1, a long noncoding RNA upregulated in lung cancer and promotes invasion and metastasis.

Zeng Z, Bo H, Gong Z, Lian Y, Li X, Li X, Zhang W, Deng H, Zhou M, Peng S, Li G, Xiong W
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jan;37(1):729-37

Septins promote macropinosome maturation and traffic to the lysosome by facilitating membrane fusion.

Dolat L, Spiliotis ET
The Journal of cell biology 2016 Aug 29;214(5):517-27

Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma.

Bo H, Gong Z, Zhang W, Li X, Zeng Y, Liao Q, Chen P, Shi L, Lian Y, Jing Y, Tang K, Li Z, Zhou Y, Zhou M, Xiang B, Li X, Yang J, Xiong W, Li G, Zeng Z
Oncotarget 2015 Aug 21;6(24):20404-18

Inactivation of MYO5B promotes invasion and motility in gastric cancer cells.

Dong W, Chen X, Chen P, Yue D, Zhu L, Fan Q
Digestive diseases and sciences 2012 May;57(5):1247-52

miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics.

Cao J, Shen Y, Zhu L, Xu Y, Zhou Y, Wu Z, Li Y, Yan X, Zhu X
Nature cell biology 2012 Jun 10;14(7):697-706

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The RAB11 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RAB11. This antibody recognizes human,mouse,rat antigen. The RAB11 antibody has been validated for the following applications: ELISA, WB analysis.
Appendix: 15903-1-AP.pdf

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