20229-1-AP

antibody from Proteintech Group

Targeting: RAB11A YL8

Provider product page for 20229-1-AP

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [31]
Comments [0]
Validations
Western blot [1]

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Product number: 20229-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#20229-1-AP, RRID:AB_10666202
Product name: RAB11A-Specific antibody
Antibody type: Polyclonal
Description: KD/KO validated RAB11A-Specific antibody (Cat. #20229-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

RAB11A protein structure - 20229-1-AP shown in red.

Submitted references Albumin fusion of the rVWF fragment rD'D3 reduces internalisation by clearance receptor Stabilin-2.

Lieu KG, Pestel S, Maxwell M, Liu YH, Bass GT, Dai Y, Glauser I, Hofmann M, Baz Morelli A, Chia J, Verhagen AM
Blood cells, molecules & diseases 2026 Mar 19;119:103000

SREBP2-RAB11A-ZDHHC20 axis orchestrates FGFR3 palmitoylation and membrane retention to drive bladder cancer progression.

Zhang WW, Qu HR, Du XS, Sun SJ, Chen PR, Deng ZH, Pan Q, Luo FL, Wu HY, Song C, Liu M
Cellular oncology (Dordrecht, Netherlands) 2026 Jan 26;49(1):30

CCDC41 Drives Oocyte Meiotic Progression by Promoting Rab11a/Rab7-Positive Vesicle Fusion with Target Membranes.

Tian Y, Li J, Kang J, Xu X, Wang B, Lou S, Li J, Yang Y, Zhang Y, Zheng Y, Weng J, Liang Y, Ma W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(8):e04665

Acute aerobic exercise alters serum protein distribution in colorectal cancer patients.

Jin S, Han S, Wang N, Yang M, Chen C
Frontiers in oncology 2025;15:1586344

Pseudorabies virus induces ferroptosis by disrupting iron homeostasis through activation of TfR1 and ferritinophagy.

Ma Z, Guo L, Ji R, Sun Z, Wang J, Yan Y, Liu K, Zhang H, Wang X, Wu C, Lian L, Cao W, Bai J, Jiang P, Liu X
Journal of virology 2025 Sep 23;99(9):e0097425

Concentration-dependent formation of intersegment interactions in the viral inclusions of influenza A virus infected cells.

Takizawa N, Higashi K, Kawaguchi RK, Gotoh Y, Hayashi T, Kurokawa K
iScience 2025 Oct 17;28(10):113606

Rab27a regulates the transport of influenza virus membrane proteins to the plasma membrane.

Chen T, Ouyang A, Zou J, Feng Y, Wu C, Jiang M, Tu S, Ding L, Cheng Y, Hu W, Sheng W, Li Y, Jin M, Chen H, Zhou H
Nature communications 2025 Jul 8;16(1):6271

Interactions between TTYH2 and APOE facilitate endosomal lipid transfer.

Sukalskaia A, Karner A, Pugnetti A, Weber F, Plochberger B, Dutzler R
Nature 2025 Aug;644(8075):273-279

TBC1D20 coordinates vesicle transport and actin remodeling to regulate ciliogenesis.

Zhai D, Li L, Wang D, Wang W, Zhao S, Wang X, Chen C, Zhu Z, Bu W, Yang M, Yin H, Shan Y, Zhao H, Westlake CJ, Lu Q, Zhou J
The Journal of cell biology 2025 Apr 4;224(4)

Coxiella burnetii-containing vacuoles interact with host recycling endosomal proteins Rab11a and Rab35 for vacuolar expansion and bacterial growth.

Hall BA, Senior KE, Ocampo NT, Samanta D
Frontiers in cellular and infection microbiology 2024;14:1394019

PLD1 promotes spindle assembly and migration through regulating autophagy in mouse oocyte meiosis.

Zhang J, Tian Y, Xu X, Wang B, Huang Z, Song K, Lou S, Kang J, Zhang N, Li J, Weng J, Liang Y, Ma W
Autophagy 2024 Jul;20(7):1616-1638

RAB22A sorts epithelial growth factor receptor (EGFR) from early endosomes to recycling endosomes for microvesicles release.

Lin Y, Wei D, He X, Huo L, Wang J, Zhang X, Wu Y, Zhang R, Gao Y, Kang T
Journal of extracellular vesicles 2024 Jul;13(7):e12494

A Novel Constitutively Active c.98G > C, p.(R33P) Variant in RAB11A Associated with Intellectual Disability Promotes Neuritogenesis and Affects Oligodendroglial Arborization.

Tsuneura Y, Kawai T, Yamada K, Aoki S, Nakashima M, Eda S, Matsuki T, Nishikawa M, Nagata KI, Enokido Y, Saitsu H, Nakayama A
Human mutation 2023;2023:8126544

Identification and validation of Rab11a in Rat orofacial inflammatory pain model induced by CFA.

Liu M, Li X, Wang J, Ji Y, Gu J, Wei Y, Peng L, Tian C, Lv P, Wang P, Liu X, Li W
Neurochemistry international 2023 Sep;168:105550

Rab11a in the spinal cord: an essential contributor to complete Freund's adjuvant-induced inflammatory pain in mice.

Gu JX, Wang J, Ma FJ, Liu MM, Chen SH, Wei Y, Xiao YF, Lv PY, Liu X, Qu JQ, Yan XX, Chen T
Molecular brain 2023 Sep 28;16(1):70

Targeting intracellular oncoproteins with dimeric IgA promotes expulsion from the cytoplasm and immune-mediated control of epithelial cancers.

Biswas S, Mandal G, Anadon CM, Chaurio RA, Lopez-Bailon LU, Nagy MZ, Mine JA, Hänggi K, Sprenger KB, Innamarato P, Harro CM, Powers JJ, Johnson J, Fang B, Eysha M, Nan X, Li R, Perez BA, Curiel TJ, Yu X, Rodriguez PC, Conejo-Garcia JR
Immunity 2023 Nov 14;56(11):2570-2583.e6

The endosomal system of primary human vascular endothelial cells and albumin-FcRn trafficking.

Pannek A, Becker-Gotot J, Dower SK, Verhagen AM, Gleeson PA
Journal of cell science 2023 Aug 1;136(15)

Rab9 Mediates Pancreatic Autophagy Switch From Canonical to Noncanonical, Aggravating Experimental Pancreatitis.

Mareninova OA, Dillon DL, Wightman CJM, Yakubov I, Takahashi T, Gaisano HY, Munson K, Ohmuraya M, Dawson D, Gukovsky I, Gukovskaya AS
Cellular and molecular gastroenterology and hepatology 2022;13(2):599-622

Metabotropic glutamate receptor 5 upregulation of γ-aminobutyric acid transporter 3 expression ameliorates cognitive impairment after traumatic brain injury in mice.

Xu P, Huang X, Niu W, Yu D, Zhou M, Wang H
Brain research bulletin 2022 Jun 1;183:104-115

Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance.

Chen Y, Wu X, Zhang J, Pan G, Wang X, Guo X, Wang J, Cui X, Gao H, Cheng M, Yang J, Zhang C, Jiang F
EMBO reports 2022 Feb 3;23(3):e53373

TBC1 domain family member 23 interacts with Ras-related protein Rab-11A to promote poor prognosis of non-small-cell lung cancer via β1-integrin.

Zhang Y, Su H, Wudu M, Ren H, Xu Y, Zhang Q, Jiang J, Wang Q, Jiang X, Zhang B, Liu Z, Zou Z, Qiu X
Journal of cellular and molecular medicine 2021 Sep;25(18):8821-8835

Rab11a mediates cell-cell spread and reassortment of influenza A virus genomes via tunneling nanotubes.

Ganti K, Han J, Manicassamy B, Lowen AC
PLoS pathogens 2021 Sep;17(9):e1009321

Increased potency of recombinant VWF D'D3 albumin fusion proteins engineered for enhanced affinity for coagulation factor VIII.

Chia J, Pestel S, Glauser I, Emmrich K, Hardy MP, Mischnik M, Raquet E, Tomasetig V, Claar P, Zalewski A, Bass GT, Turnbull V, Chen CG, Wilson MJ, Panousis C, Weimer T, Andrews A, Verhagen AM, Dower SK
Journal of thrombosis and haemostasis : JTH 2021 Nov;19(11):2710-2725

Visualizing Coronavirus Entry into Cells.

Milewska A, Owczarek K, Szczepanski A, Pyrc K
Methods in molecular biology (Clifton, N.J.) 2020;2203:241-261

DIAPH1 regulates ciliogenesis and trafficking in primary cilia.

Palander O, Trimble WS
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16516-16535

An orally available hypoglycaemic peptide taken up by caveolae transcytosis displays improved hypoglycaemic effects and body weight control in db/db mice.

Lu W, Tian H, Qian P, Li Y, Wang Y, Ge Y, Sai W, Gao X, Yao W
British journal of pharmacology 2020 Aug;177(15):3473-3488

Tsg101 positively regulates physiologic-like cardiac hypertrophy through FIP3-mediated endosomal recycling of IGF-1R.

Essandoh K, Deng S, Wang X, Jiang M, Mu X, Peng J, Li Y, Peng T, Wagner KU, Rubinstein J, Fan GC
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jun;33(6):7451-7466

Upregulation and hypomethylation of lncRNA AFAP1‑AS1 predicts a poor prognosis and promotes the migration and invasion of cervical cancer.

Bo H, Fan L, Gong Z, Liu Z, Shi L, Guo C, Li X, Liao Q, Zhang W, Zhou M, Xiang B, Li X, Li G, Xiong W, Zeng Z, Cao K, Zhang S, Xiong F
Oncology reports 2019 Apr;41(4):2431-2439

Canine Salivary Glands: Analysis of Rab and SNARE Protein Expression and SNARE Complex Formation With Diverse Tissue Properties.

Gomi H, Osawa H, Uno R, Yasui T, Hosaka M, Torii S, Tsukise A
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2017 Nov;65(11):637-653

BLOC-1 is required for selective membrane protein trafficking from endosomes to primary cilia.

Monis WJ, Faundez V, Pazour GJ
The Journal of cell biology 2017 Jul 3;216(7):2131-2150

ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting.

Humbert MC, Weihbrecht K, Searby CC, Li Y, Pope RM, Sheffield VC, Seo S
Proceedings of the National Academy of Sciences of the United States of America 2012 Nov 27;109(48):19691-6

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: human brain tissue were subjected to SDS PAGE followed by western blot with 20229-1-AP(RAB11A-Specific antibody) at dilution of 1:500
Sample type: tissue