Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 18149-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18149-1-AP, RRID:AB_2276580
- Product name
- CPLX2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CPLX2 antibody (Cat. #18149-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references CPLX2 is a novel tumor suppressor and improves the prognosis in glioma.
Geniposide improves depression-like behavior in prenatal stress male offspring through restoring HPA axis- and glucocorticoid receptor-associated dysfunction.
L116 Deletion in CSPα Promotes α-Synuclein Aggregation and Neurodegeneration.
Long non-coding RNA LncCplx2 regulates glucose homeostasis and pancreatic β cell function.
Nicotinamide adenine dinucleotide treatment confers resistance to neonatal ischemia and hypoxia: effects on neurobehavioral phenotypes.
Absence of BBSome function leads to astrocyte reactivity in the brain.
Widespread cerebellar transcriptome changes in Ts65Dn Down syndrome mouse model after lifelong running.
Complexin-2 (CPLX2) as a potential prognostic biomarker in human lung high grade neuroendocrine tumors.
NOX2 deficiency ameliorates cerebral injury through reduction of complexin II-mediated glutamate excitotoxicity in experimental stroke.
Chen Y, Ning J, Shu L, Wen L, Yan B, Wang Z, Hu J, Zhou X, Tao Y, Xia X, Huang J
Journal of neuro-oncology 2024 Mar;167(1):63-74
Journal of neuro-oncology 2024 Mar;167(1):63-74
Geniposide improves depression-like behavior in prenatal stress male offspring through restoring HPA axis- and glucocorticoid receptor-associated dysfunction.
Ma Y, Li SX, Zhou RY, Deng LJ, le He W, Guo LL, Wang L, Hao JH, Li Y, Fang MF, Cao YJ
Life sciences 2024 Mar 1;340:122434
Life sciences 2024 Mar 1;340:122434
L116 Deletion in CSPα Promotes α-Synuclein Aggregation and Neurodegeneration.
Guo T, Xiong J, Feng H, Bu L, Xiao T, Zhou L, He J, Deng M, Liu Y, Zhang Z, Zhang Z
Molecular neurobiology 2024 Jan;61(1):15-27
Molecular neurobiology 2024 Jan;61(1):15-27
Long non-coding RNA LncCplx2 regulates glucose homeostasis and pancreatic β cell function.
Wang L, Hu L, Wang X, Geng Z, Wan M, Hao J, Liu H, Fan Y, Xu T, Li Z
Molecular metabolism 2024 Feb;80:101878
Molecular metabolism 2024 Feb;80:101878
Nicotinamide adenine dinucleotide treatment confers resistance to neonatal ischemia and hypoxia: effects on neurobehavioral phenotypes.
Xu X, Wang X, Zhang L, Jin Y, Li L, Jin M, Li L, Ni H
Neural regeneration research 2024 Dec 1;19(12):2760-2772
Neural regeneration research 2024 Dec 1;19(12):2760-2772
Absence of BBSome function leads to astrocyte reactivity in the brain.
Singh M, Garrison JE, Wang K, Sheffield VC
Molecular brain 2019 May 9;12(1):48
Molecular brain 2019 May 9;12(1):48
Widespread cerebellar transcriptome changes in Ts65Dn Down syndrome mouse model after lifelong running.
Walus M, Kida E, Rabe A, Albertini G, Golabek AA
Behavioural brain research 2016 Jan 1;296:35-46
Behavioural brain research 2016 Jan 1;296:35-46
Complexin-2 (CPLX2) as a potential prognostic biomarker in human lung high grade neuroendocrine tumors.
Komatsu H, Kakehashi A, Nishiyama N, Izumi N, Mizuguchi S, Yamano S, Inoue H, Hanada S, Chung K, Wei M, Suehiro S, Wanibuchi H
Cancer biomarkers : section A of Disease markers 2013;13(3):171-80
Cancer biomarkers : section A of Disease markers 2013;13(3):171-80
NOX2 deficiency ameliorates cerebral injury through reduction of complexin II-mediated glutamate excitotoxicity in experimental stroke.
Wang Z, Wei X, Liu K, Zhang X, Yang F, Zhang H, He Y, Zhu T, Li F, Shi W, Zhang Y, Xu H, Liu J, Yi F
Free radical biology & medicine 2013 Dec;65:942-951
Free radical biology & medicine 2013 Dec;65:942-951
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 18149-1-AP(CPLX2 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-CPLX2 (IP:18149-1-AP, 3ug; Detection:18149-1-AP 1:700) with SH-SY5Y cells lysate 800ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 18149-1-AP(CPLX2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CPLX2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CPLX2. This antibody recognizes human,mouse,rat antigen. The CPLX2 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.