Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- 10-7573-25 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-MLH1 Antibody
- Antibody type
- Monoclonal
- Description
- MutL homolog 1 (MLH1) is a member of mismatch repair genes (MMR) that plays a crucial role in correcting replication errors, cell cycle arrest, apoptosis and oxidative stress. MLH1 is a human homolog of the E.coli DNA mismatch repair gene. It mediates protein-protein interactions during mismatch recognition, strand discrimination, and strand removal. Diseases associated with MLH1 include colorectal cancer, hereditary nonpolyposis, type 2 and lynch syndrome.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
A partial length recombinant MLH1 p
rotein (amino acids 289-492) was us
ed as the immunogen for this antibo
dy.- Isotype
- IgG
- Antibody clone number
- ABM4D74
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freez thawing
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Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of MLH1 in Lymphoma tissue using MLH1 antibody (Clone: ABM4D74) at 5 µg/ml.
- Protocol
- Protocol