AMM03801G

antibody from Leading Biology

Targeting: MLH1 COCA2, FCC2, HNPCC, HNPCC2

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

AMM03801G

Provider

Leading Biology

Product name

MLH1 Antibody (monoclonal) (M02)

Antibody type

Monoclonal

Description

This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

M1

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.