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- Antibody Data
- Antigen structure
- References [11]
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- Validations
- Western blot [1]
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- Product number
- 10726-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10726-1-AP, RRID:AB_2062475
- Product name
- ATIC antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ATIC antibody (Cat. #10726-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A MXene nanoplatform for psoriasis therapy: Synergistic scavenging of ROS and cfDNA to target inflammation and proliferation.
Native chromatome profiling reveals hundreds of metabolic enzymes in the nucleus across tissues.
Investigation of the effects and underlying mechanisms of adenylate kinase 1 on inosine monophosphate deposition in Beijing-You chickens.
Aerobic exercise ameliorates skeletal muscle atrophy in atic knockout zebrafish through the oxidative phosphorylation pathway.
LncRNA ZFAS1 regulates ATIC transcription and promotes the proliferation and migration of hepatocellular carcinoma through the PI3K/AKT signaling pathway.
De novo and salvage purine synthesis pathways across tissues and tumors.
Oxoglutarate dehydrogenase-like inhibits the progression of hepatocellular carcinoma by inducing DNA damage through non-canonical function.
ATIC inhibits autophagy in hepatocellular cancer through the AKT/FOXO3 pathway and serves as a prognostic signature for modeling patient survival.
Psychosocial and behavioral problems of children and adolescents in the early stage of reopening schools after the COVID-19 pandemic: a national cross-sectional study in China.
Melatonin modulates metabolic remodeling in HNSCC by suppressing MTHFD1L-formate axis.
Bifunctional enzyme ATIC promotes propagation of hepatocellular carcinoma by regulating AMPK-mTOR-S6 K1 signaling.
Lei H, Lin Z, Chen X, Mou K, Xu F, Zheng Y, Xie L
Free radical biology & medicine 2026 May;248:74-86
Free radical biology & medicine 2026 May;248:74-86
Native chromatome profiling reveals hundreds of metabolic enzymes in the nucleus across tissues.
Kourtis S, Gañez Zapater A, Elbæk CR, Schmidt A, Ghose R, Coll Manzano A, Espinar Calvo L, Guirola M, Pardo-Lorente N, Garcia-Cao M, Pfeiffer M, Haynes S, Fontaine F, Müller A, Sdelci S
Nature communications 2026 Mar 6;17(1)
Nature communications 2026 Mar 6;17(1)
Investigation of the effects and underlying mechanisms of adenylate kinase 1 on inosine monophosphate deposition in Beijing-You chickens.
Hou J, Zhang Y, Zhu L, Qi X, Wang X, Lin Z, Xiao L, Long C, Dou J, Xu Y, Sheng X
Poultry science 2026 Mar 23;105(6):106828
Poultry science 2026 Mar 23;105(6):106828
Aerobic exercise ameliorates skeletal muscle atrophy in atic knockout zebrafish through the oxidative phosphorylation pathway.
Peng Z, Yang T, Xu S, Yang B, Zhang Z, Ding M, Gu W, Zheng L
Free radical biology & medicine 2025 Oct;238:653-668
Free radical biology & medicine 2025 Oct;238:653-668
LncRNA ZFAS1 regulates ATIC transcription and promotes the proliferation and migration of hepatocellular carcinoma through the PI3K/AKT signaling pathway.
Luo B, Zhuang L, Huang J, Shi L, Zhang L, Zhu M, Lu Y, Zhu Q, Sun D, Wang H, Fang H
Journal of cancer research and clinical oncology 2024 Jul 13;150(7):351
Journal of cancer research and clinical oncology 2024 Jul 13;150(7):351
De novo and salvage purine synthesis pathways across tissues and tumors.
Tran DH, Kim D, Kesavan R, Brown H, Dey T, Soflaee MH, Vu HS, Tasdogan A, Guo J, Bezwada D, Al Saad H, Cai F, Solmonson A, Rion H, Chabatya R, Merchant S, Manales NJ, Tcheuyap VT, Mulkey M, Mathews TP, Brugarolas J, Morrison SJ, Zhu H, DeBerardinis RJ, Hoxhaj G
Cell 2024 Jul 11;187(14):3602-3618.e20
Cell 2024 Jul 11;187(14):3602-3618.e20
Oxoglutarate dehydrogenase-like inhibits the progression of hepatocellular carcinoma by inducing DNA damage through non-canonical function.
Jiang X, Peng J, Xie Y, Xu Y, Liu Q, Cheng C, Yan P, Xu S, Wang Y, Zhang L, Li H, Li Y, Li B, Han J, Yu D
Cell death and differentiation 2023 Aug;30(8):1931-1942
Cell death and differentiation 2023 Aug;30(8):1931-1942
ATIC inhibits autophagy in hepatocellular cancer through the AKT/FOXO3 pathway and serves as a prognostic signature for modeling patient survival.
Zhang H, Xia P, Liu J, Chen Z, Ma W, Yuan Y
International journal of biological sciences 2021;17(15):4442-4458
International journal of biological sciences 2021;17(15):4442-4458
Psychosocial and behavioral problems of children and adolescents in the early stage of reopening schools after the COVID-19 pandemic: a national cross-sectional study in China.
Wang L, Zhang Y, Chen L, Wang J, Jia F, Li F, Froehlich TE, Hou Y, Hao Y, Shi Y, Deng H, Zhang J, Huang L, Xie X, Fang S, Xu L, Xu Q, Guan H, Wang W, Shen J, Qian Y, Wang X, Shan L, Tan C, Yu Y, Wang X, Chen F, Zhang L, Li X, Shi X, Ke X, Li T
Translational psychiatry 2021 Jun 3;11(1):342
Translational psychiatry 2021 Jun 3;11(1):342
Melatonin modulates metabolic remodeling in HNSCC by suppressing MTHFD1L-formate axis.
Cui L, Zhao X, Jin Z, Wang H, Yang SF, Hu S
Journal of pineal research 2021 Dec;71(4):e12767
Journal of pineal research 2021 Dec;71(4):e12767
Bifunctional enzyme ATIC promotes propagation of hepatocellular carcinoma by regulating AMPK-mTOR-S6 K1 signaling.
Li M, Jin C, Xu M, Zhou L, Li D, Yin Y
Cell communication and signaling : CCS 2017 Dec 16;15(1):52
Cell communication and signaling : CCS 2017 Dec 16;15(1):52
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ATIC antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ATIC. This antibody recognizes human antigen. The ATIC antibody has been validated for the following applications: ELISA, WB analysis.
