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- References [11]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 22696-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#22696-1-AP, RRID:AB_11182926
- Product name
- AARS2 antibody
- Antibody type
- Polyclonal
- Description
- AARS2 antibody (Cat. #22696-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references NPM3 functions as a lactyltransferase to promote necroptosis in male diabetic cardiomyopathy mice models via FASN transcription modulation.
Targeting MYC in T-Cell lymphoma via epigenetic modulation with a small-molecule inhibitor.
Hyperglycemia impairs cognitive function by inducing mitochondrial damage through lactylation of LRPPRC at K223.
A novel, rapid, and practical prognostic model for sepsis patients based on dysregulated immune cell lactylation.
KAT8-mediated MDH2 lactylation promotes renal cancer progression by enhancing mitochondrial function and stress resistance.
Lactylation of CREB is required for FSH-induced proliferation and differentiation of ovarian granulosa cells.
Mitochondrial alanyl-tRNA synthetase 2 mediates histone lactylation to promote ferroptosis in intestinal ischemia-reperfusion injury.
Hypoxia induces mitochondrial protein lactylation to limit oxidative phosphorylation.
AARS2 as a novel biomarker for prognosis and its molecular characterization in pan-cancer.
Integrated proteogenomic characterization of urothelial carcinoma of the bladder.
A small-molecule cocktail promotes mammalian cardiomyocyte proliferation and heart regeneration.
Xu H, Jiang X, Wang F, Meng F, Liu Y, Huang J, Li J, Zhu M
Nature communications 2026 Mar 9;17(1)
Nature communications 2026 Mar 9;17(1)
Targeting MYC in T-Cell lymphoma via epigenetic modulation with a small-molecule inhibitor.
Liu B, Jiang B, Liu S, Zhang S, Huang Z, Zhang M, Zhao X, Li Q, Li X, Xia J, Huang D, Li H, Luo X, Ma N, Hu Y, Zhang X, Rao J
Molecular cancer 2026 Mar 13;25(1)
Molecular cancer 2026 Mar 13;25(1)
Hyperglycemia impairs cognitive function by inducing mitochondrial damage through lactylation of LRPPRC at K223.
Xu J, Hao Y, Cao J, Yang X, Gao Y, Sun X, Nie R, Zhong Q, Zhong Y, Zhong J, Zheng T
EMBO molecular medicine 2026 Apr 6;
EMBO molecular medicine 2026 Apr 6;
A novel, rapid, and practical prognostic model for sepsis patients based on dysregulated immune cell lactylation.
Li C, He M, Shi P, Yao L, Fang X, Li X, Li Q, Yang X, Xu J, Shang Y
Frontiers in immunology 2025;16:1625311
Frontiers in immunology 2025;16:1625311
KAT8-mediated MDH2 lactylation promotes renal cancer progression by enhancing mitochondrial function and stress resistance.
Tang Y, Dai C, Yang H, Yang X, Chen Z, Dou J, Zhang L, Bai T, Zheng J
International journal of biological macromolecules 2025 Sep;322(Pt 1):146571
International journal of biological macromolecules 2025 Sep;322(Pt 1):146571
Lactylation of CREB is required for FSH-induced proliferation and differentiation of ovarian granulosa cells.
Wu G, Chen M, He T, Pan Y, Li C, Liu Z, Li H, Sheng Y, Dai W, Shen M, Liu H
Nucleic acids research 2025 Sep 5;53(17)
Nucleic acids research 2025 Sep 5;53(17)
Mitochondrial alanyl-tRNA synthetase 2 mediates histone lactylation to promote ferroptosis in intestinal ischemia-reperfusion injury.
Dong W, Huang SX, Qin ML, Pan Z
World journal of gastrointestinal surgery 2025 Jun 27;17(6):106777
World journal of gastrointestinal surgery 2025 Jun 27;17(6):106777
Hypoxia induces mitochondrial protein lactylation to limit oxidative phosphorylation.
Mao Y, Zhang J, Zhou Q, He X, Zheng Z, Wei Y, Zhou K, Lin Y, Yu H, Zhang H, Zhou Y, Lin P, Wu B, Yuan Y, Zhao J, Xu W, Zhao S
Cell research 2024 Jan;34(1):13-30
Cell research 2024 Jan;34(1):13-30
AARS2 as a novel biomarker for prognosis and its molecular characterization in pan-cancer.
Liu L, Gao J, Liu X, Zhang F, Hu B, Zhang H, Wang Z, Tang H, Shi JH, Zhang S
Cancer medicine 2023 Dec;12(23):21531-21544
Cancer medicine 2023 Dec;12(23):21531-21544
Integrated proteogenomic characterization of urothelial carcinoma of the bladder.
Xu N, Yao Z, Shang G, Ye D, Wang H, Zhang H, Qu Y, Xu F, Wang Y, Qin Z, Zhu J, Zhang F, Feng J, Tian S, Liu Y, Zhao J, Hou J, Guo J, Hou Y, Ding C
Journal of hematology & oncology 2022 Jun 3;15(1):76
Journal of hematology & oncology 2022 Jun 3;15(1):76
A small-molecule cocktail promotes mammalian cardiomyocyte proliferation and heart regeneration.
Du J, Zheng L, Gao P, Yang H, Yang WJ, Guo F, Liang R, Feng M, Wang Z, Zhang Z, Bai L, Bu Y, Xing S, Zheng W, Wang X, Quan L, Hu X, Wu H, Chen Z, Chen L, Wei K, Zhang Z, Zhu X, Zhang X, Tu Q, Zhao SM, Lei X, Xiong JW
Cell stem cell 2022 Apr 7;29(4):545-558.e13
Cell stem cell 2022 Apr 7;29(4):545-558.e13
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- K-562 cells were subjected to SDS PAGE followed by western blot with 22696-1-AP(AARS2 antibody) at dilution of 1:3000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The AARS2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human AARS2. This antibody recognizes human antigen. The AARS2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
