Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 20219-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20219-1-AP, RRID:AB_10694675
- Product name
- ROBO1-Specific antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ROBO1-Specific antibody (Cat. #20219-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Recombinant Slit2 attenuates tracheal fibroblast activation in benign central airway obstruction by inhibiting the TGF-β1/Smad3 signaling pathway.
Repression of Smad3 by silencing Robo1 attenuates epithelial-mesenchymal transition in tracheobronchial stenosis.
PIEZO2 promotes cell proliferation and metastasis in colon carcinoma through the SLIT2/ROBO1/VEGFC pathway.
Cancer associated fibroblast derived SLIT2 drives gastric cancer cell metastasis by activating NEK9.
RNA m6A reader IGF2BP3 promotes metastasis of triple-negative breast cancer via SLIT2 repression.
AKT constitutes a signal-promoted alternative exon-junction complex that regulates nonsense-mediated mRNA decay.
Mechanistic Targets of Diallyl Trisulfide in Human Breast Cancer Cells Identified by RNA-seq Analysis.
Role of Slit2 upregulation in recurrent miscarriage through regulation of stromal decidualization.
MicroRNA-29a-3p delivery via exosomes derived from engineered human mesenchymal stem cells exerts tumour suppressive effects by inhibiting migration and vasculogenic mimicry in glioma.
Activation of EPHA2-ROBO1 Heterodimer by SLIT2 Attenuates Non-canonical Signaling and Proliferation in Squamous Cell Carcinomas.
Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins.
A crucial role for Arf6 in the response of commissural axons to Slit.
Slit2/Robo1 signaling is involved in angiogenesis of glomerular endothelial cells exposed to a diabetic-like environment.
Alterted SLIT2/ROBO1 signalling is linked to impaired placentation of missed and threatened miscarriage in early pregnancy.
MicroRNA-219-5p exerts tumor suppressor function by targeting ROBO1 in glioblastoma.
USP33, a new player in lung cancer, mediates Slit-Robo signaling.
He C, Gu L, Li A, Li Y, Xiao R, Liao J, Mu J, Gan Y, Peng M, Mohan G, Liu W, Xu L, Guo S
Molecular and cellular probes 2024 Feb;73:101947
Molecular and cellular probes 2024 Feb;73:101947
Repression of Smad3 by silencing Robo1 attenuates epithelial-mesenchymal transition in tracheobronchial stenosis.
He C, Li A, Gu L, Xiao R, Liao J, Gan Y, Peng M, Guo S
Chinese medical journal 2023 Sep 5;136(17):2125-2127
Chinese medical journal 2023 Sep 5;136(17):2125-2127
PIEZO2 promotes cell proliferation and metastasis in colon carcinoma through the SLIT2/ROBO1/VEGFC pathway.
Shang H, Xu A, Yan H, Xu D, Zhang J, Fang X
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2023 Jul;32(7):763-776
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2023 Jul;32(7):763-776
Cancer associated fibroblast derived SLIT2 drives gastric cancer cell metastasis by activating NEK9.
Lu G, Du R, Dong J, Sun Y, Zhou F, Feng F, Feng B, Han Y, Shang Y
Cell death & disease 2023 Jul 13;14(7):421
Cell death & disease 2023 Jul 13;14(7):421
RNA m6A reader IGF2BP3 promotes metastasis of triple-negative breast cancer via SLIT2 repression.
Jiang T, He X, Zhao Z, Zhang X, Wang T, Jia L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Nov;36(11):e22618
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Nov;36(11):e22618
AKT constitutes a signal-promoted alternative exon-junction complex that regulates nonsense-mediated mRNA decay.
Cho H, Abshire ET, Popp MW, Pröschel C, Schwartz JL, Yeo GW, Maquat LE
Molecular cell 2022 Aug 4;82(15):2779-2796.e10
Molecular cell 2022 Aug 4;82(15):2779-2796.e10
Mechanistic Targets of Diallyl Trisulfide in Human Breast Cancer Cells Identified by RNA-seq Analysis.
Hahm ER, Kim SH, Mathan SV, Singh RP, Singh SV
Journal of cancer prevention 2021 Jun 30;26(2):128-136
Journal of cancer prevention 2021 Jun 30;26(2):128-136
Role of Slit2 upregulation in recurrent miscarriage through regulation of stromal decidualization.
Chen J, Liu J, Gao S, Qiu Y, Wang Y, Zhang Y, Gao L, Qi G, Wu Y, Lash GE, Li P
Placenta 2021 Jan 1;103:1-9
Placenta 2021 Jan 1;103:1-9
MicroRNA-29a-3p delivery via exosomes derived from engineered human mesenchymal stem cells exerts tumour suppressive effects by inhibiting migration and vasculogenic mimicry in glioma.
Zhang Z, Guo X, Guo X, Yu R, Qian M, Wang S, Gao X, Qiu W, Guo Q, Xu J, Chen Z, Wang H, Qi Y, Zhao R, Xue H, Li G
Aging 2021 Feb 1;13(4):5055-5068
Aging 2021 Feb 1;13(4):5055-5068
Activation of EPHA2-ROBO1 Heterodimer by SLIT2 Attenuates Non-canonical Signaling and Proliferation in Squamous Cell Carcinomas.
Srivastava S, Pang KM, Iida M, Nelson MS, Liu J, Nam A, Wang J, Mambetsariev I, Pillai R, Mohanty A, McDaniel N, Behal A, Kulkarni P, Wheeler DL, Salgia R
iScience 2020 Nov 20;23(11):101692
iScience 2020 Nov 20;23(11):101692
Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins.
Simonetti B, Paul B, Chaudhari K, Weeratunga S, Steinberg F, Gorla M, Heesom KJ, Bashaw GJ, Collins BM, Cullen PJ
Nature cell biology 2019 Oct;21(10):1219-1233
Nature cell biology 2019 Oct;21(10):1219-1233
A crucial role for Arf6 in the response of commissural axons to Slit.
Kinoshita-Kawada M, Hasegawa H, Hongu T, Yanagi S, Kanaho Y, Masai I, Mishima T, Chen X, Tsuboi Y, Rao Y, Yuasa-Kawada J, Wu JY
Development (Cambridge, England) 2019 Feb 4;146(3)
Development (Cambridge, England) 2019 Feb 4;146(3)
Slit2/Robo1 signaling is involved in angiogenesis of glomerular endothelial cells exposed to a diabetic-like environment.
Liu J, Hou W, Guan T, Tang L, Zhu X, Li Y, Hou S, Zhang J, Chen H, Huang Y
Angiogenesis 2018 May;21(2):237-249
Angiogenesis 2018 May;21(2):237-249
Alterted SLIT2/ROBO1 signalling is linked to impaired placentation of missed and threatened miscarriage in early pregnancy.
Li P, Shi Y, Shuai H, Cai Y, Lu W, Wang G, Gao L, Wang L, Fan X, Yang X
Histopathology 2017 Oct;71(4):543-552
Histopathology 2017 Oct;71(4):543-552
MicroRNA-219-5p exerts tumor suppressor function by targeting ROBO1 in glioblastoma.
Jiang Y, Yin L, Jing H, Zhang H
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Nov;36(11):8943-51
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Nov;36(11):8943-51
USP33, a new player in lung cancer, mediates Slit-Robo signaling.
Wen P, Kong R, Liu J, Zhu L, Chen X, Li X, Nie Y, Wu K, Wu JY
Protein & cell 2014 Sep;5(9):704-13
Protein & cell 2014 Sep;5(9):704-13
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ROBO1-Specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human ROBO1-Specific. This antibody recognizes human, mouse antigen. The ROBO1-Specific antibody has been validated for the following applications: ELISA, WB analysis.
