Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 14716-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14716-1-AP, RRID:AB_10640526
- Product name
- KLF6 antibody
- Antibody type
- Polyclonal
- Description
- KLF6 antibody (Cat. #14716-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Silencing KLF6 Alleviates Cigarette Smoke Extract-Induced Mitochondrial Dysfunction in Bronchial Epithelial Cells by SIRT4 Upregulation.
The Krüppel-like factor 6 represses proliferation and invasion of cutaneous malignant melanoma.
Klf6 aggravates myocardial ischemia/reperfusion injury by activating Acsl4-mediated ferroptosis.
MicroRNA-22-3p Regulates the Apoptosis of Lens Epithelial Cells Through Targeting KLF6 in Diabetic Cataracts.
Exosomal miR-181d-5p Derived from Rapamycin-Conditioned MDSC Alleviated Allograft Rejection by Targeting KLF6.
Succinylation of CTBP1 mediated by KAT2A suppresses its inhibitory activity on the transcription of CDH1 to promote the progression of prostate cancer.
Revealing Potential Spinal Cord Injury Biomarkers and Immune Cell Infiltration Characteristics in Mice.
MicroRNA-124 modulates neuroinflammation in acute methanol poisoning rats via targeting Krüppel-like factor-6.
Bone marrow mesenchymal stem cell-derived extracellular vesicles containing miR-181d protect rats against renal fibrosis by inhibiting KLF6 and the NF-κB signaling pathway.
MiR-181d-5p Targets KLF6 to Improve Ischemia/Reperfusion-Induced AKI Through Effects on Renal Function, Apoptosis, and Inflammation.
Salvia miltiorrhiza bunge exerts anti-oxidative effects through inhibiting KLF10 expression in vascular smooth muscle cells exposed to high glucose.
Hotspot mutant p53-R273H inhibits KLF6 expression to promote cell migration and tumor metastasis.
Artesunate induces mitochondria-mediated apoptosis of human retinoblastoma cells by upregulating Kruppel-like factor 6.
Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes.
The Growth of SGC-7901 Tumor Xenografts Was Suppressed by Chinese Bayberry Anthocyanin Extract through Upregulating KLF6 Gene Expression.
Wan M, Wang C, Cui J, Xia Q, Zhang L
International journal of chronic obstructive pulmonary disease 2024;19:815-828
International journal of chronic obstructive pulmonary disease 2024;19:815-828
The Krüppel-like factor 6 represses proliferation and invasion of cutaneous malignant melanoma.
Li YY, Zheng QM, Zhang N, Zhang M
Polish journal of pathology : official journal of the Polish Society of Pathologists 2023;74(3):194-202
Polish journal of pathology : official journal of the Polish Society of Pathologists 2023;74(3):194-202
Klf6 aggravates myocardial ischemia/reperfusion injury by activating Acsl4-mediated ferroptosis.
Qiu ML, Yan W, Liu MM
The Kaohsiung journal of medical sciences 2023 Oct;39(10):989-1001
The Kaohsiung journal of medical sciences 2023 Oct;39(10):989-1001
MicroRNA-22-3p Regulates the Apoptosis of Lens Epithelial Cells Through Targeting KLF6 in Diabetic Cataracts.
Yin X, Chen L, Shen J, Bi Z, Chen C, Zhao X, Liu S, Li Y
Translational vision science & technology 2023 May 1;12(5):9
Translational vision science & technology 2023 May 1;12(5):9
Exosomal miR-181d-5p Derived from Rapamycin-Conditioned MDSC Alleviated Allograft Rejection by Targeting KLF6.
Wei C, Sun Y, Zeng F, Chen X, Ma L, Liu X, Qi X, Shi W, Gao H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(34):e2304922
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(34):e2304922
Succinylation of CTBP1 mediated by KAT2A suppresses its inhibitory activity on the transcription of CDH1 to promote the progression of prostate cancer.
Zhou J, Yan X, Liu Y, Yang J
Biochemical and biophysical research communications 2023 Apr 2;650:9-16
Biochemical and biophysical research communications 2023 Apr 2;650:9-16
Revealing Potential Spinal Cord Injury Biomarkers and Immune Cell Infiltration Characteristics in Mice.
Cao L, Li Q
Frontiers in genetics 2022;13:883810
Frontiers in genetics 2022;13:883810
MicroRNA-124 modulates neuroinflammation in acute methanol poisoning rats via targeting Krüppel-like factor-6.
Zhou S, Li J, Zhang X, Xiong W
Bioengineered 2022 May;13(5):13507-13519
Bioengineered 2022 May;13(5):13507-13519
Bone marrow mesenchymal stem cell-derived extracellular vesicles containing miR-181d protect rats against renal fibrosis by inhibiting KLF6 and the NF-κB signaling pathway.
Wang SJ, Qiu ZZ, Chen FW, Mao AL, Bai JC, Hong YJ, Zhang ZP, Zhu WA, Zhang ZW, Zhou H
Cell death & disease 2022 Jun 7;13(6):535
Cell death & disease 2022 Jun 7;13(6):535
MiR-181d-5p Targets KLF6 to Improve Ischemia/Reperfusion-Induced AKI Through Effects on Renal Function, Apoptosis, and Inflammation.
Zhang Y, Li C, Guan C, Zhou B, Wang L, Yang C, Zhen L, Dai J, Zhao L, Jiang W, Xu Y
Frontiers in physiology 2020;11:510
Frontiers in physiology 2020;11:510
Salvia miltiorrhiza bunge exerts anti-oxidative effects through inhibiting KLF10 expression in vascular smooth muscle cells exposed to high glucose.
Zhou J, Zhang L, Zheng B, Zhang L, Qin Y, Zhang X, Yang Z, Nie Z, Yang G, Yu J, Wen J
Journal of ethnopharmacology 2020 Nov 15;262:113208
Journal of ethnopharmacology 2020 Nov 15;262:113208
Hotspot mutant p53-R273H inhibits KLF6 expression to promote cell migration and tumor metastasis.
Sun S, Chen H, Sun L, Wang M, Wu X, Xiao ZJ
Cell death & disease 2020 Jul 30;11(7):595
Cell death & disease 2020 Jul 30;11(7):595
Artesunate induces mitochondria-mediated apoptosis of human retinoblastoma cells by upregulating Kruppel-like factor 6.
Yang Y, Wu N, Wu Y, Chen H, Qiu J, Qian X, Zeng J, Chiu K, Gao Q, Zhuang J
Cell death & disease 2019 Nov 13;10(11):862
Cell death & disease 2019 Nov 13;10(11):862
Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes.
Suzuki T, Kikuguchi C, Nishijima S, Nagashima T, Takahashi A, Okada M, Yamamoto T
Development (Cambridge, England) 2019 Feb 15;146(4)
Development (Cambridge, England) 2019 Feb 15;146(4)
The Growth of SGC-7901 Tumor Xenografts Was Suppressed by Chinese Bayberry Anthocyanin Extract through Upregulating KLF6 Gene Expression.
Wang Y, Zhang XN, Xie WH, Zheng YX, Cao JP, Cao PR, Chen QJ, Li X, Sun CD
Nutrients 2016 Sep 27;8(10)
Nutrients 2016 Sep 27;8(10)
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 14716-1-AP(KLF6 antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The KLF6 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human KLF6. This antibody recognizes human,mouse,rat antigen. The KLF6 antibody has been validated for the following applications: ELISA, WB, IHC analysis.