Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 11847-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11847-1-AP, RRID:AB_2195400
- Product name
- SPCS1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SPCS1 antibody (Cat. #11847-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Signal peptidase complex mediates rotavirus VP7 processing and virion assembly.
HTLV-1 p12 is cleaved to p8 by the signal peptidase complex and its inhibition impairs p8-dependent transmission.
Signal peptidase complex mediates rotavirus VP7 processing and virion assembly.
Cleavage of the pseudoprotease iRhom2 by the signal peptidase complex reveals an ER-to-nucleus signaling pathway.
SPCS1-Dependent E2-p7 processing determines HCV Assembly efficiency.
A CRISPR screen defines a signal peptide processing pathway required by flaviviruses.
Signal peptidase complex subunit 1 participates in the assembly of hepatitis C virus through an interaction with E2 and NS2.
Zhu X, Li E, Sanchez-Tacuba L, Beatty W, Li B, Ding S
PLoS pathogens 2026 Mar;22(3):e1013688
PLoS pathogens 2026 Mar;22(3):e1013688
HTLV-1 p12 is cleaved to p8 by the signal peptidase complex and its inhibition impairs p8-dependent transmission.
Simon F, Donhauser N, Kemeter LM, Wittdorf F, Millen S, Sticht H, Thoma-Kress AK
PLoS pathogens 2025 Oct;21(10):e1013570
PLoS pathogens 2025 Oct;21(10):e1013570
Signal peptidase complex mediates rotavirus VP7 processing and virion assembly.
Zhu X, Sanchez-Tacuba L, Beatty W, Li B, Ding S
bioRxiv : the preprint server for biology 2025 Nov 4;
bioRxiv : the preprint server for biology 2025 Nov 4;
Cleavage of the pseudoprotease iRhom2 by the signal peptidase complex reveals an ER-to-nucleus signaling pathway.
Dulloo I, Tellier M, Levet C, Chikh A, Zhang B, Blaydon DC, Webb CM, Kelsell DP, Freeman M
Molecular cell 2024 Jan 18;84(2):277-292.e9
Molecular cell 2024 Jan 18;84(2):277-292.e9
SPCS1-Dependent E2-p7 processing determines HCV Assembly efficiency.
Alzahrani N, Wu MJ, Sousa CF, Kalinina OV, Welsch C, Yi M
PLoS pathogens 2022 Feb;18(2):e1010310
PLoS pathogens 2022 Feb;18(2):e1010310
A CRISPR screen defines a signal peptide processing pathway required by flaviviruses.
Zhang R, Miner JJ, Gorman MJ, Rausch K, Ramage H, White JP, Zuiani A, Zhang P, Fernandez E, Zhang Q, Dowd KA, Pierson TC, Cherry S, Diamond MS
Nature 2016 Jul 7;535(7610):164-8
Nature 2016 Jul 7;535(7610):164-8
Signal peptidase complex subunit 1 participates in the assembly of hepatitis C virus through an interaction with E2 and NS2.
Suzuki R, Matsuda M, Watashi K, Aizaki H, Matsuura Y, Wakita T, Suzuki T
PLoS pathogens 2013;9(8):e1003589
PLoS pathogens 2013;9(8):e1003589
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human skin tissue were subjected to SDS PAGE followed by western blot with 11847-1-AP(SPCS1 antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SPCS1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SPCS1. This antibody recognizes human, mouse, rat antigen. The SPCS1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
