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LearnPA5-51902
antibody from Invitrogen Antibodies
Targeting: RNF213
ALO17, C17orf27, KIAA1554, KIAA1618, MYMY2, NET57
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Immunocytochemistry [2]
- Immunohistochemistry [5]
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- Product number
- PA5-51902 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- RNF213 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant protein fragment
- Description
- Immunogen sequence: VGKNEQGEPE DLKKPEGKNR SAAAVKNEKE QKNQEADVQE VKASTLSPGG GVTVFFHAII SLHFPFNPDL HKVFIRGGEE FGESKWDSNI CELHYTRDLG HDRVLVEGIV CISKKHLDKY IPYKYVIYNG ESFEYEFIYK H Highest antigen sequence identity to the following orthologs: Mouse - 47%, Rat - 48%.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 0.10 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references Sequential ubiquitination of NLRP3 by RNF125 and Cbl-b limits inflammasome activation and endotoxemia.
Tang J, Tu S, Lin G, Guo H, Yan C, Liu Q, Huang L, Tang N, Xiao Y, Pope RM, Rajaram MVS, Amer AO, Ahmer BM, Gunn JS, Wozniak DJ, Tao L, Coppola V, Zhang L, Langdon WY, Torrelles JB, Lipkowitz S, Zhang J
The Journal of experimental medicine 2020 Apr 6;217(4)
The Journal of experimental medicine 2020 Apr 6;217(4)
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of RNF213 in human cell line A-431 shows positivity in cytoplasm. Samples were probed using a RNF213 Polyclonal Antibody (Product # PA5-51902).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorecent analysis of RNF213 in human cell line A-431 using RNF213 Polyclonal Antibody (Product # PA5-51902). Staining shows localization to cytosol.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of RNF213 in human kidney using RNF213 Polyclonal Antibody (Product # PA5-51902) shows moderate cytoplasmic positivity in cells in tubules.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of RNF213 in human lung using RNF213 Polyclonal Antibody (Product # PA5-51902) shows moderate cytoplasmic positivity in macrophages.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of RNF213 in human rectum using RNF213 Polyclonal Antibody (Product # PA5-51902) shows moderate cytoplasmic positivity in glandular cells.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of RNF213 in human cerebral cortex using a RNF213 Polyclonal Antibody (Product # PA5-51902) shows strong cytoplasmic and nuclear positivity in neuronal cells.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of RNF213 in human cerebral cortex using a RNF213 Polyclonal Antibody (Product # PA5-51902) shows strong cytoplasmic and nuclear positivity in neuronal cells.
