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- Antigen structure
- References [9]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 24543-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- ZNF746 antibody
- Antibody type
- Polyclonal
- Description
- ZNF746 antibody (Cat. #24543-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Manganese-induced PINK1 S-nitrosylation exacerbates nerve cell damage by promoting ZNF746 repression of mitochondrial biogenesis.
Obesity-induced PARIS (ZNF746) accumulation in adipose progenitor cells leads to attenuated mitochondrial biogenesis and impaired adipogenesis.
Proximity proteomic analysis of the NRF family reveals the Parkinson's disease protein ZNF746/PARIS as a co-complexed repressor of NRF2.
Identification and evaluation of midbrain specific longevity-related genes in exceptionally long-lived but healthy mice.
Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson's disease.
Deubiquitinase CYLD acts as a negative regulator of dopamine neuron survival in Parkinson's disease.
ZNF746/PARIS promotes the occurrence of hepatocellular carcinoma.
Parkin interacting substrate phosphorylation by c-Abl drives dopaminergic neurodegeneration.
Parkin interacting substrate zinc finger protein 746 is a pathological mediator in Parkinson's disease.
Liu K, Liu Z, Liu Z, Ma Z, Jia Y, Deng Y, Liu W, Xu B
The Science of the total environment 2023 Mar 10;863:160985
The Science of the total environment 2023 Mar 10;863:160985
Obesity-induced PARIS (ZNF746) accumulation in adipose progenitor cells leads to attenuated mitochondrial biogenesis and impaired adipogenesis.
Hachiya K, Deguchi Y, Hirata T, Arikawa T, Fukai H, Esashi T, Nagasawa K, Mizunoe Y, Nozaki Y, Kobayashi M, Higami Y
Scientific reports 2023 Dec 27;13(1):22990
Scientific reports 2023 Dec 27;13(1):22990
Proximity proteomic analysis of the NRF family reveals the Parkinson's disease protein ZNF746/PARIS as a co-complexed repressor of NRF2.
LaPak KM, Saeidi S, Bok I, Wamsley NT, Plutzer IB, Bhatt DP, Luo J, Ashrafi G, Ben Major M
Science signaling 2023 Dec 12;16(815):eadi9018
Science signaling 2023 Dec 12;16(815):eadi9018
Identification and evaluation of midbrain specific longevity-related genes in exceptionally long-lived but healthy mice.
Kim H, Huh YJ, Kim JH, Jo M, Shin JH, Park SC, Ahn JY, Lee YI, Lee Y
Frontiers in aging neuroscience 2022;14:1030807
Frontiers in aging neuroscience 2022;14:1030807
Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson's disease.
Panicker N, Kam TI, Wang H, Neifert S, Chou SC, Kumar M, Brahmachari S, Jhaldiyal A, Hinkle JT, Akkentli F, Mao X, Xu E, Karuppagounder SS, Hsu ET, Kang SU, Pletnikova O, Troncoso J, Dawson VL, Dawson TM
Neuron 2022 Aug 3;110(15):2422-2437.e9
Neuron 2022 Aug 3;110(15):2422-2437.e9
Deubiquitinase CYLD acts as a negative regulator of dopamine neuron survival in Parkinson's disease.
Pirooznia SK, Wang H, Panicker N, Kumar M, Neifert S, Dar MA, Lau E, Kang BG, Redding-Ochoa J, Troncoso JC, Dawson VL, Dawson TM
Science advances 2022 Apr;8(13):eabh1824
Science advances 2022 Apr;8(13):eabh1824
ZNF746/PARIS promotes the occurrence of hepatocellular carcinoma.
Kim H, Lee JY, Park SJ, Kwag E, Koo O, Shin JH
Biochemical and biophysical research communications 2021 Jul 23;563:98-104
Biochemical and biophysical research communications 2021 Jul 23;563:98-104
Parkin interacting substrate phosphorylation by c-Abl drives dopaminergic neurodegeneration.
Kim H, Shin JY, Jo A, Kim JH, Park S, Choi JY, Kang HC, Dawson VL, Dawson TM, Shin JH, Lee Y
Brain : a journal of neurology 2021 Dec 31;144(12):3674-3691
Brain : a journal of neurology 2021 Dec 31;144(12):3674-3691
Parkin interacting substrate zinc finger protein 746 is a pathological mediator in Parkinson's disease.
Brahmachari S, Lee S, Kim S, Yuan C, Karuppagounder SS, Ge P, Shi R, Kim EJ, Liu A, Kim D, Quintin S, Jiang H, Kumar M, Yun SP, Kam TI, Mao X, Lee Y, Swing DA, Tessarollo L, Ko HS, Dawson VL, Dawson TM
Brain : a journal of neurology 2019 Aug 1;142(8):2380-2401
Brain : a journal of neurology 2019 Aug 1;142(8):2380-2401
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 24543-1-AP( ZNF746 Antibody) at dilution of 1:1000
- Other comments
- WB
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ZNF746 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ZNF746. This antibody recognizes human, mouse antigen. The ZNF746 antibody has been validated for the following applications: ELISA, IHC, WB analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemistry of paraffin-embedded human testis tissue slide using 24543-1-AP( ZNF746 Antibody) at dilution of 1:50 (under 10x lens)
- Other comments
- IHC
