PA5-51652
antibody from Invitrogen Antibodies
Targeting: UPF3B
HUPF3B, MRX62, MRX82, RENT3B, UPF3BP1, UPF3BP2, UPF3BP3, UPF3X
Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PA5-51652 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- UPF3B Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full-length protein
- Description
- Immunogen sequence: KEEKEHRPKE KRVTLLTPAG ATGSGGGTSG DSSKGEDKQD RNKEKKEALS KVVIRRLPPT LTKEQLQEHL QPMPEHDYFE FFSNDTSLYP HMYARAYINF KNQEDIILFR DRFDGYVFLD NKGQEYPAIV E Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 87%.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 0.10 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references C9orf72 arginine-rich dipeptide repeats inhibit UPF1-mediated RNA decay via translational repression.
Sun Y, Eshov A, Zhou J, Isiktas AU, Guo JU
Nature communications 2020 Jul 3;11(1):3354
Nature communications 2020 Jul 3;11(1):3354
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of UPF3B in Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells); Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells). Samples were probed using an UPF3B Polyclonal Antibody (Product # PA5-51652).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of UPF3B in human cell line U-2 OS shows positivity in cytoplasm. Samples were probed using an UPF3B Polyclonal Antibody (Product # PA5-51652).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of UPF3B in human placenta shows moderate cytoplasmic positivity in trophoblastic and decidual cells. Samples were probed using an UPF3B Polyclonal Antibody (Product # PA5-51652).