ZNF304

This gene encodes a member of the Krueppel C2H2-type zinc-finger family of proteins. The encoded protein functions as a transcriptional repressor that recruits a corepressor complex to stimulate promoter hypermethylation and transcriptional silencing of target genes. Expression of this gene is upregulated in colorectal, ovarian and breast cancer, and this gene may promote cancer cell survival, growth and invasion. [provided by RefSeq, Jul 2016]

Description

Zinc finger protein 304

Tissue specificity

Low tissue specificity

Subcell location

Nuclear speckles, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Transcription factors

Chromosome

19 (57351271 - 57359898)

Ensembl ID

ENSG00000131845  (ver. 103.38)

Orthologs

-

UniProt

Q9HCX3

neXtProt

NX_Q9HCX3

Human splice variants

Protein structure