Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 17603-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17603-1-AP, RRID:AB_2181073
- Product name
- RSPH3 antibody
- Antibody type
- Polyclonal
- Description
- RSPH3 antibody (Cat. #17603-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Multi-scale structures of the mammalian radial spoke and divergence of axonemal complexes in ependymal cilia.
Whole-exome sequencing identifies ADGB as a novel causative gene for male infertility in humans: from motility to fertilization.
Adenylate kinase phosphate energy shuttle underlies energetic communication in flagellar axonemes.
Novel HYDIN variants associated with male infertility in two Chinese families.
CFAP70 is a solid and valuable target for the genetic diagnosis of oligo-astheno-teratozoospermia in infertile men.
CCDC176 stabilizes microtubule doublets 1 and 9 to ensure proper sperm movement.
Differential requirements of IQUB for the assembly of radial spoke 1 and the motility of mouse cilia and flagella.
Loss of Rsph9 causes neonatal hydrocephalus with abnormal development of motile cilia in mice.
Patients with severe asthenoteratospermia carrying SPAG6 or RSPH3 mutations have a positive pregnancy outcome following intracytoplasmic sperm injection.
Vertebrate Dynein-f depends on Wdr78 for axonemal localization and is essential for ciliary beat.
Meng X, Xu C, Li J, Qiu B, Luo J, Hong Q, Tong Y, Fang C, Feng Y, Ma R, Shi X, Lin C, Pan C, Zhu X, Yan X, Cong Y
Nature communications 2024 Jan 8;15(1):362
Nature communications 2024 Jan 8;15(1):362
Whole-exome sequencing identifies ADGB as a novel causative gene for male infertility in humans: from motility to fertilization.
Gao Y, Liu L, Tian S, Liu C, Lv M, Wu H, Tang D, Song B, Shen Q, Xu Y, Zhou P, Wei Z, Zhang F, Cao Y, He X
Andrology 2024 Feb 22;
Andrology 2024 Feb 22;
Adenylate kinase phosphate energy shuttle underlies energetic communication in flagellar axonemes.
Wu H, Zhang Y, Li Y, Sun S, Zhang J, Xie Q, Dong Y, Zhou S, Sha X, Li K, Chen J, Zhang X, Gao Y, Shen Q, Wang G, Zha X, Duan Z, Tang D, Xu C, Geng H, Lv M, Xu Y, Zhou P, Wei Z, Hua R, Cao Y, Liu M, He X
Science China. Life sciences 2024 Aug;67(8):1697-1714
Science China. Life sciences 2024 Aug;67(8):1697-1714
Novel HYDIN variants associated with male infertility in two Chinese families.
Yu H, Shi X, Shao Z, Geng H, Guo S, Li K, Gu M, Xu C, Gao Y, Tan Q, Duan Z, Wu H, Hua R, Guo R, Wei Z, Zhou P, Cao Y, He X, Li L, Zhang X, Lv M
Frontiers in endocrinology 2023;14:1118841
Frontiers in endocrinology 2023;14:1118841
CFAP70 is a solid and valuable target for the genetic diagnosis of oligo-astheno-teratozoospermia in infertile men.
Jin HJ, Wang JL, Geng XY, Wang CY, Wang BB, Chen SR
EBioMedicine 2023 Jul;93:104675
EBioMedicine 2023 Jul;93:104675
CCDC176 stabilizes microtubule doublets 1 and 9 to ensure proper sperm movement.
Liu C, Wang Q, Gu L, Wang X, Yin Y, Huang T, Xiao S, Zhang S, Wang F, Zhou T, Xu G, Wang L, Dong F, Jiang J, Luo M, Li J, Zhang H, Zi-Jiang Chen, Ji W, Ji B, Liu H, Li W
Current biology : CB 2023 Aug 21;33(16):3371-3388.e7
Current biology : CB 2023 Aug 21;33(16):3371-3388.e7
Differential requirements of IQUB for the assembly of radial spoke 1 and the motility of mouse cilia and flagella.
Zhang X, Xiao Z, Zhang J, Xu C, Liu S, Cheng L, Zhou S, Zhao S, Zhang Y, Wu J, Wang Y, Liu M
Cell reports 2022 Nov 22;41(8):111683
Cell reports 2022 Nov 22;41(8):111683
Loss of Rsph9 causes neonatal hydrocephalus with abnormal development of motile cilia in mice.
Zou W, Lv Y, Liu ZI, Xia P, Li H, Jiao J
Scientific reports 2020 Jul 24;10(1):12435
Scientific reports 2020 Jul 24;10(1):12435
Patients with severe asthenoteratospermia carrying SPAG6 or RSPH3 mutations have a positive pregnancy outcome following intracytoplasmic sperm injection.
Wu H, Wang J, Cheng H, Gao Y, Liu W, Zhang Z, Jiang H, Li W, Zhu F, Lv M, Liu C, Tan Q, Zhang X, Wang C, Ni X, Chen Y, Song B, Zhou P, Wei Z, Zhang F, He X, Cao Y
Journal of assisted reproduction and genetics 2020 Apr;37(4):829-840
Journal of assisted reproduction and genetics 2020 Apr;37(4):829-840
Vertebrate Dynein-f depends on Wdr78 for axonemal localization and is essential for ciliary beat.
Zhang Y, Chen Y, Zheng J, Wang J, Duan S, Zhang W, Yan X, Zhu X
Journal of molecular cell biology 2019 May 1;11(5):383-394
Journal of molecular cell biology 2019 May 1;11(5):383-394
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 17603-1-AP(RSPH3 antibody) at dilution of 1:600
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 17603-1-AP(RSPH3 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RSPH3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RSPH3. This antibody recognizes human, mouse, rat antigen. The RSPH3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.