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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 17750-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17750-1-AP, RRID:AB_2281443
- Product name
- LSG1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated LSG1 antibody (Cat. #17750-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Portimine A toxin causes skin inflammation through ZAKα-dependent NLRP1 inflammasome activation.
The Ribosome Assembly Factor LSG1 Interacts with Vesicle-Associated Membrane Protein-Associated Proteins (VAPs).
Inhibition of the 60S ribosome biogenesis GTPase LSG1 causes endoplasmic reticular disruption and cellular senescence.
Gorse L, Plessis L, Wearne S, Paradis M, Pinilla M, Chua R, Lim SS, Pelluz E, Toh GA, Mazars R, Bomfim C, Hervé F, Lhaute K, Réveillon D, Suire B, Ravon-Katossky L, Benoist T, Fromont L, Péricat D, Neil Mertens K, Derrien A, Terre-Terrillon A, Chomérat N, Bilien G, Séchet V, Carpentier L, Fall M, Sonko A, Hakim H, Sadio N, Bourdeaux J, Cougoule C, Henras AK, Perez-Oliva AB, Brehmer P, Roca FJ, Zhong FL, Common J, Meunier E, Hess P
EMBO molecular medicine 2025 Mar;17(3):535-562
EMBO molecular medicine 2025 Mar;17(3):535-562
The Ribosome Assembly Factor LSG1 Interacts with Vesicle-Associated Membrane Protein-Associated Proteins (VAPs).
Sutjita P, Musalgaonkar S, Recchia-Rife J, Huang L, Xhemalce B, Johnson AW
Molecular and cellular biology 2024;44(9):345-357
Molecular and cellular biology 2024;44(9):345-357
Inhibition of the 60S ribosome biogenesis GTPase LSG1 causes endoplasmic reticular disruption and cellular senescence.
Pantazi A, Quintanilla A, Hari P, Tarrats N, Parasyraki E, Dix FL, Patel J, Chandra T, Acosta JC, Finch AJ
Aging cell 2019 Aug;18(4):e12981
Aging cell 2019 Aug;18(4):e12981
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 17750-1-AP(LSG1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 17750-1-AP(LSG1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The LSG1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human LSG1. This antibody recognizes human, mouse, rat antigen. The LSG1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
