Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 19122-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19122-1-AP, RRID:AB_10597247
- Product name
- FOXO6 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated FOXO6 antibody (Cat. #19122-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references FOXO6 transcription inhibition of CTRP3 promotes OGD/R-triggered cardiac microvascular endothelial barrier disruption via SIRT1/Nrf2 signalling.
Oxyberberine sensitizes liver cancer cells to sorafenib via inhibiting NOTCH1-USP7-c-Myc pathway.
Forkhead box O6 (FoxO6) promotes cardiac pathological remodeling and dysfunction by activating Kif15-TGF-β1 under aggravated afterload.
Inflammatory Cell-Derived MYDGF Attenuates Endothelial LDL Transcytosis to Protect Against Atherogenesis.
FOXO signaling pathway participates in oxidative stress-induced histone deacetylation.
SGK2 promotes prostate cancer metastasis by inhibiting ferroptosis via upregulating GPX4.
PLOD3 contributes to HER-2 therapy resistance in gastric cancer through FoxO3/Survivin pathway.
Activation of angiotensin-converting enzyme 2/angiotensin (1-7)/mas receptor axis triggers autophagy and suppresses microglia proinflammatory polarization via forkhead box class O1 signaling.
Role and mechanism underlying FoxO6 in skeletal muscle in vitro and in vivo.
Enterotoxigenic Escherichia coli infection promotes enteric defensin expression via FOXO6-METTL3-m(6)A-GPR161 signalling axis.
Involvement of the FOXO6 transcriptional factor in breast carcinogenesis.
Elevated FOXO6 expression correlates with progression and prognosis in gastric cancer.
Dormant Pluripotent Cells Emerge during Neural Differentiation of Embryonic Stem Cells in a FoxO3-Dependent Manner.
Inhibition of mutant EGFR in lung cancer cells triggers SOX2-FOXO6-dependent survival pathways.
Zheng S, Wang Y, Guo W, Tan H
Folia morphologica 2024;83(1):125-138
Folia morphologica 2024;83(1):125-138
Oxyberberine sensitizes liver cancer cells to sorafenib via inhibiting NOTCH1-USP7-c-Myc pathway.
Sun L, He M, Li F, Wu D, Zheng P, Zhang C, Liu Y, Liu D, Shan M, Yang M, Ma Y, Lian J, Xiong H
Hepatology communications 2024 Apr 1;8(4)
Hepatology communications 2024 Apr 1;8(4)
Forkhead box O6 (FoxO6) promotes cardiac pathological remodeling and dysfunction by activating Kif15-TGF-β1 under aggravated afterload.
Zhang B, Shi L, Tan Y, Zhou Y, Cui J, Song Y, Liu Y, Zhang M, Duan W, Jin Z, Liu J, Yi D, Sun Y, Yi W
MedComm 2023 Oct;4(5):e383
MedComm 2023 Oct;4(5):e383
Inflammatory Cell-Derived MYDGF Attenuates Endothelial LDL Transcytosis to Protect Against Atherogenesis.
Xu J, Ma H, Shi L, Zhou H, Cheng Y, Tong J, Meng B, Xu X, He K, Ding S, Zhang J, Yue L, Xiang G
Arteriosclerosis, thrombosis, and vascular biology 2023 Nov;43(11):e443-e467
Arteriosclerosis, thrombosis, and vascular biology 2023 Nov;43(11):e443-e467
FOXO signaling pathway participates in oxidative stress-induced histone deacetylation.
Zuo M, Tong R, He X, Liu Y, Liu J, Liu S, Liu Y, Cao J, Ma L
Free radical research 2023 Jan;57(1):47-60
Free radical research 2023 Jan;57(1):47-60
SGK2 promotes prostate cancer metastasis by inhibiting ferroptosis via upregulating GPX4.
Cheng L, He Q, Liu B, Chen L, Lv F, Li X, Li Y, Liu C, Song Y, Xing Y
Cell death & disease 2023 Jan 31;14(1):74
Cell death & disease 2023 Jan 31;14(1):74
PLOD3 contributes to HER-2 therapy resistance in gastric cancer through FoxO3/Survivin pathway.
Chen Y, Ye B, Wang C, Nie Y, Qin J, Shen Z
Cell death discovery 2022 Jul 14;8(1):321
Cell death discovery 2022 Jul 14;8(1):321
Activation of angiotensin-converting enzyme 2/angiotensin (1-7)/mas receptor axis triggers autophagy and suppresses microglia proinflammatory polarization via forkhead box class O1 signaling.
Dang R, Yang M, Cui C, Wang C, Zhang W, Geng C, Han W, Jiang P
Aging cell 2021 Oct;20(10):e13480
Aging cell 2021 Oct;20(10):e13480
Role and mechanism underlying FoxO6 in skeletal muscle in vitro and in vivo.
Zhang L, Zhang Y, Zhou M, Wang S, Li T, Hu Z, Jin C
International journal of molecular medicine 2021 Jul;48(1)
International journal of molecular medicine 2021 Jul;48(1)
Enterotoxigenic Escherichia coli infection promotes enteric defensin expression via FOXO6-METTL3-m(6)A-GPR161 signalling axis.
Zong X, Wang H, Xiao X, Zhang Y, Hu Y, Wang F, Wang Y, Lu Z
RNA biology 2021 Apr;18(4):576-586
RNA biology 2021 Apr;18(4):576-586
Involvement of the FOXO6 transcriptional factor in breast carcinogenesis.
Lallemand F, Petitalot A, Vacher S, de Koning L, Taouis K, Lopez BS, Zinn-Justin S, Dalla-Venezia N, Chemlali W, Schnitzler A, Lidereau R, Bieche I, Caputo SM
Oncotarget 2018 Jan 26;9(7):7464-7475
Oncotarget 2018 Jan 26;9(7):7464-7475
Elevated FOXO6 expression correlates with progression and prognosis in gastric cancer.
Wang JH, Tang HS, Li XS, Zhang XL, Yang XZ, Zeng LS, Ruan Q, Huang YH, Liu GJ, Wang J, Cui SZ
Oncotarget 2017 May 9;8(19):31682-31691
Oncotarget 2017 May 9;8(19):31682-31691
Dormant Pluripotent Cells Emerge during Neural Differentiation of Embryonic Stem Cells in a FoxO3-Dependent Manner.
Ikeda M, Toyoshima F
Molecular and cellular biology 2017 Mar 1;37(5)
Molecular and cellular biology 2017 Mar 1;37(5)
Inhibition of mutant EGFR in lung cancer cells triggers SOX2-FOXO6-dependent survival pathways.
Rothenberg SM, Concannon K, Cullen S, Boulay G, Turke AB, Faber AC, Lockerman EL, Rivera MN, Engelman JA, Maheswaran S, Haber DA
eLife 2015 Feb 16;4
eLife 2015 Feb 16;4
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 19122-1-AP(FOXO6 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human gliomas using 19122-1-AP(FOXO6 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The FOXO6 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human FOXO6. This antibody recognizes human, mouse, rat antigen. The FOXO6 antibody has been validated for the following applications: ELISA, WB, IHC analysis.