Antibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- BS7496 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- MYSM1 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human MYSM1.
- Description
- MYSM1 (myb-like, SWIRM and MPN domains 1), also known as 2ADUB or KIAA1915, is an 828 amino acid nuclear protein that contains one SWIRM domain, one SANT domain and one MPN domain and exists as multiple alternatively spliced isoforms. Expressed ubiquitously with highest expression in kidney, brain and spleen, MYSM1 functions to bind double-stranded DNA and may positively regulate the transcriptional activity of AR (androgen receptor), possibly via control of histone acetylation and deubiquitination. The gene encoding MYSM1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinsons Disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot analysis of MYSM1 polyclonal antibody