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- Antibody Data
- Antigen structure
- References [11]
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- Western blot [1]
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- Product number
- 17401-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17401-1-AP, RRID:AB_2180990
- Product name
- RPAP2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RPAP2 antibody (Cat. #17401-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Identification of hub genes and potential therapeutic mechanisms related to HPV positive head and neck squamous carcinoma based on full transcriptomic detection and ceRNA network construction.
Super enhancers targeting ZBTB16 in osteogenesis protect against osteoporosis.
TGFβ1 regulates HRas-mediated activation of IRE1α through the PERK-RPAP2 axis in keratinocytes.
Modulation of the Pol II CTD Phosphorylation Code by Rac1 and Cdc42 Small GTPases in Cultured Human Cancer Cells and Its Implication for Developing a Synthetic-Lethal Cancer Therapy.
Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate.
Abnormal expression of RNA polymerase II-associated proteins in muscle of patients with myofibrillar myopathies.
Herpes Simplex Virus 1 (HSV-1) ICP22 protein directly interacts with cyclin-dependent kinase (CDK)9 to inhibit RNA polymerase II transcription elongation.
RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation.
Nuclear import of RNA polymerase II is coupled with nucleocytoplasmic shuttling of the RNA polymerase II-associated protein 2.
Ser7 phosphorylation of the CTD recruits the RPAP2 Ser5 phosphatase to snRNA genes.
Control of the RNA polymerase II phosphorylation state in promoter regions by CTD interaction domain-containing proteins RPRD1A and RPRD1B.
Wang K, Zhang T, Li X, Zhang X, Li R, Pan B, Deng J
Gene 2024 Jun 5;910:148321
Gene 2024 Jun 5;910:148321
Super enhancers targeting ZBTB16 in osteogenesis protect against osteoporosis.
Yu W, Xie Z, Li J, Lin J, Su Z, Che Y, Ye F, Zhang Z, Xu P, Zeng Y, Xu X, Li Z, Feng P, Mi R, Wu Y, Shen H
Bone research 2023 Jun 7;11(1):30
Bone research 2023 Jun 7;11(1):30
TGFβ1 regulates HRas-mediated activation of IRE1α through the PERK-RPAP2 axis in keratinocytes.
Mogre S, Blazanin N, Walsh H, Ibinson J, Minnich C, Andrew Hu CC, Glick AB
Molecular carcinogenesis 2022 Oct;61(10):958-971
Molecular carcinogenesis 2022 Oct;61(10):958-971
Modulation of the Pol II CTD Phosphorylation Code by Rac1 and Cdc42 Small GTPases in Cultured Human Cancer Cells and Its Implication for Developing a Synthetic-Lethal Cancer Therapy.
Zhang B, Zhong X, Sauane M, Zhao Y, Zheng ZL
Cells 2020 Mar 4;9(3)
Cells 2020 Mar 4;9(3)
Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate.
Chang TK, Lawrence DA, Lu M, Tan J, Harnoss JM, Marsters SA, Liu P, Sandoval W, Martin SE, Ashkenazi A
Molecular cell 2018 Aug 16;71(4):629-636.e5
Molecular cell 2018 Aug 16;71(4):629-636.e5
Abnormal expression of RNA polymerase II-associated proteins in muscle of patients with myofibrillar myopathies.
Guglielmi V, Marini M, Masson ÉF, Malatesta M, Forget D, Tomelleri G, Coulombe B, Vattemi G
Histopathology 2015 Dec;67(6):859-65
Histopathology 2015 Dec;67(6):859-65
Herpes Simplex Virus 1 (HSV-1) ICP22 protein directly interacts with cyclin-dependent kinase (CDK)9 to inhibit RNA polymerase II transcription elongation.
Zaborowska J, Baumli S, Laitem C, O'Reilly D, Thomas PH, O'Hare P, Murphy S
PloS one 2014;9(9):e107654
PloS one 2014;9(9):e107654
RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation.
Ni Z, Xu C, Guo X, Hunter GO, Kuznetsova OV, Tempel W, Marcon E, Zhong G, Guo H, Kuo WW, Li J, Young P, Olsen JB, Wan C, Loppnau P, El Bakkouri M, Senisterra GA, He H, Huang H, Sidhu SS, Emili A, Murphy S, Mosley AL, Arrowsmith CH, Min J, Greenblatt JF
Nature structural & molecular biology 2014 Aug;21(8):686-695
Nature structural & molecular biology 2014 Aug;21(8):686-695
Nuclear import of RNA polymerase II is coupled with nucleocytoplasmic shuttling of the RNA polymerase II-associated protein 2.
Forget D, Lacombe AA, Cloutier P, Lavallée-Adam M, Blanchette M, Coulombe B
Nucleic acids research 2013 Aug;41(14):6881-91
Nucleic acids research 2013 Aug;41(14):6881-91
Ser7 phosphorylation of the CTD recruits the RPAP2 Ser5 phosphatase to snRNA genes.
Egloff S, Zaborowska J, Laitem C, Kiss T, Murphy S
Molecular cell 2012 Jan 13;45(1):111-22
Molecular cell 2012 Jan 13;45(1):111-22
Control of the RNA polymerase II phosphorylation state in promoter regions by CTD interaction domain-containing proteins RPRD1A and RPRD1B.
Ni Z, Olsen JB, Guo X, Zhong G, Ruan ED, Marcon E, Young P, Guo H, Li J, Moffat J, Emili A, Greenblatt JF
Transcription 2011 Sep-Oct;2(5):237-42
Transcription 2011 Sep-Oct;2(5):237-42
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RPAP2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RPAP2. This antibody recognizes human, mouse, rat antigen. The RPAP2 antibody has been validated for the following applications: ELISA, WB analysis.
