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- Antigen structure
- References [26]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 12713-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12713-1-AP, RRID:AB_2173314
- Product name
- QSOX1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated QSOX1 antibody (Cat. #12713-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Proteomic Portrait of Degranulation Program in Human Circulating Neutrophils Upon Multi-Inflammatory and Infectious Activation.
Mesenchymal stem cells derived EXO-miR3671 delivery promoted angiogenesis and accelerated wound healing of diabetes.
Analysis and verification of potential ferroptosis-related diagnostic markers in the early stage of metabolic dysfunction-associated steatohepatitis.
Identify and analyze ferroptosis-related molecular modules and immune signatures in epilepsy using microarray-based transcriptome profiling and single-cell sequencing.
Could the cell nucleus be a new destination for QSOX1 under thermal stress?
Stromal QSOX1 loss is a distinctive feature of colorectal cancer and correlates with tumor expansion.
Enhanced secretion of promyogenic exosomes by quiescent muscle cells.
QSOX1 Modulates Glioblastoma Cell Proliferation and Migration In Vitro and Invasion In Vivo.
QSOX1 exerts anti-inflammatory effects in sepsis-induced acute lung injury: Regulation involving EGFR phosphorylation mediated M1 polarization of macrophages.
Caveolae-mediated endocytosis of extracellular QSOX1b modulates the migration of fibroblasts.
Elucidating ferroptosis mechanisms in heart failure through transcriptomics, single-cell sequencing, and experimental validation.
Mining host candidate regulators of schistosomiasis-induced liver fibrosis in response to artesunate therapy through transcriptomics approach.
Secretion of the disulfide bond generating catalyst QSOX1 from pancreatic tumor cells into the extracellular matrix: association with extracellular vesicles and matrix proteins.
Quiescin sulfhydryl oxidase 1 promotes sorafenib-induced ferroptosis in hepatocellular carcinoma by driving EGFR endosomal trafficking and inhibiting NRF2 activation.
A Preliminary Proteomic Investigation of Circulating Exosomes and Discovery of Biomarkers Associated with the Progression of Osteosarcoma in a Clinical Model of Spontaneous Disease.
Enhanced Biosynthesis Performance of Heterologous Proteins in CHO-K1 Cells Using CRISPR-Cas9.
High expression of QSOX1 is associated with tumor invasiveness and high grades groups in prostate cancer.
Reduced QSOX1 enhances radioresistance in nasopharyngeal carcinoma.
QSOX1 expression is associated with aggressive tumor features and reduced survival in breast carcinomas.
Identification of P-glycoprotein co-fractionating proteins and specific binding partners in rat brain microvessels.
The emerging role of QSOX1 in cancer.
Expression of quiescin sulfhydryl oxidase 1 is associated with a highly invasive phenotype and correlates with a poor prognosis in Luminal B breast cancer.
High expression of QSOX1 reduces tumorogenesis, and is associated with a better outcome for breast cancer patients.
Vitamin K epoxide reductase contributes to protein disulfide formation and redox homeostasis within the endoplasmic reticulum.
Quiescin sulfhydryl oxidase 1 promotes invasion of pancreatic tumor cells mediated by matrix metalloproteinases.
Analysis of the plasma peptidome from pancreas cancer patients connects a peptide in plasma to overexpression of the parent protein in tumors.
Hua Y, Zhou Z, Zhang C, Fang H, Wu M, Chen Z, Ku X, Yan W
Molecular & cellular proteomics : MCP 2026 Jan;25(1):101078
Molecular & cellular proteomics : MCP 2026 Jan;25(1):101078
Mesenchymal stem cells derived EXO-miR3671 delivery promoted angiogenesis and accelerated wound healing of diabetes.
Li J, Chen S, Wang H, Wang W, Liu Y
Stem cells (Dayton, Ohio) 2026 Apr 25;44(5)
Stem cells (Dayton, Ohio) 2026 Apr 25;44(5)
Analysis and verification of potential ferroptosis-related diagnostic markers in the early stage of metabolic dysfunction-associated steatohepatitis.
Li Q, Zhang Q, Ren A, Zhang H, Liu L
Biochemical and biophysical research communications 2025 Sep 12;779:152406
Biochemical and biophysical research communications 2025 Sep 12;779:152406
Identify and analyze ferroptosis-related molecular modules and immune signatures in epilepsy using microarray-based transcriptome profiling and single-cell sequencing.
Huang C, Wei F, You Z, Li J, Liu Y, Liu X, Fan Z, He Y, Gao X, Sun J
Gene 2025 Mar 20;942:149227
Gene 2025 Mar 20;942:149227
Could the cell nucleus be a new destination for QSOX1 under thermal stress?
Martinez PA, Ferreira S, Sanz CL, Costa MES, Yoshimoto HM, Zanata SM, Nakao LS
Biochemical and biophysical research communications 2025 Mar 1;750:151423
Biochemical and biophysical research communications 2025 Mar 1;750:151423
Stromal QSOX1 loss is a distinctive feature of colorectal cancer and correlates with tumor expansion.
Michalichyn ÂC, Bonilha HC, de Noronha L, Saad CT, Muzzi JCD, Eble JA, Zanata SM, Marconi C, Nakao LS
Histochemistry and cell biology 2025 Dec 24;164(1):1
Histochemistry and cell biology 2025 Dec 24;164(1):1
Enhanced secretion of promyogenic exosomes by quiescent muscle cells.
Devan P, Ghosh A, Rao T P, Raychaudhuri S, Adicherla H, Devanshi H, Kshetrapal P, Dhawan J
Frontiers in cell and developmental biology 2024;12:1381357
Frontiers in cell and developmental biology 2024;12:1381357
QSOX1 Modulates Glioblastoma Cell Proliferation and Migration In Vitro and Invasion In Vivo.
Dutt R, Thorpe C, Galileo DS
Cancers 2024 Oct 26;16(21)
Cancers 2024 Oct 26;16(21)
QSOX1 exerts anti-inflammatory effects in sepsis-induced acute lung injury: Regulation involving EGFR phosphorylation mediated M1 polarization of macrophages.
Tong W, Song C, Jin D, Li M, Cheng Z, Lu G, Yang B, Deng F
The international journal of biochemistry & cell biology 2024 Nov;176:106651
The international journal of biochemistry & cell biology 2024 Nov;176:106651
Caveolae-mediated endocytosis of extracellular QSOX1b modulates the migration of fibroblasts.
Martinez PA, Zanata SM, Nakao LS
Experimental cell research 2024 Feb 1;435(1):113906
Experimental cell research 2024 Feb 1;435(1):113906
Elucidating ferroptosis mechanisms in heart failure through transcriptomics, single-cell sequencing, and experimental validation.
Li K, Liu P, Han L, Tian J, Zheng Z, Sha M, Ye J, Zhu L
Cellular signalling 2024 Dec;124:111416
Cellular signalling 2024 Dec;124:111416
Mining host candidate regulators of schistosomiasis-induced liver fibrosis in response to artesunate therapy through transcriptomics approach.
Yuan Y, Lv X, Wu Y, Weng Y, Dai F, Ding H, Chen R, Zheng B, Zhao W, Tong Q, Ding J, Lou D, Lai Y, Chu X, Zhao L, Lu S, Kong Q
PLoS neglected tropical diseases 2023 Sep;17(9):e0011626
PLoS neglected tropical diseases 2023 Sep;17(9):e0011626
Secretion of the disulfide bond generating catalyst QSOX1 from pancreatic tumor cells into the extracellular matrix: association with extracellular vesicles and matrix proteins.
Millar-Haskell CS, Sperduto JL, Slater JH, Thorpe C, Gleghorn JP
Journal of extracellular biology 2022 Jul;1(7)
Journal of extracellular biology 2022 Jul;1(7)
Quiescin sulfhydryl oxidase 1 promotes sorafenib-induced ferroptosis in hepatocellular carcinoma by driving EGFR endosomal trafficking and inhibiting NRF2 activation.
Sun J, Zhou C, Zhao Y, Zhang X, Chen W, Zhou Q, Hu B, Gao D, Raatz L, Wang Z, Nelson PJ, Jiang Y, Ren N, Bruns CJ, Zhou H
Redox biology 2021 May;41:101942
Redox biology 2021 May;41:101942
A Preliminary Proteomic Investigation of Circulating Exosomes and Discovery of Biomarkers Associated with the Progression of Osteosarcoma in a Clinical Model of Spontaneous Disease.
Brady JV, Troyer RM, Ramsey SA, Leeper H, Yang L, Maier CS, Goodall CP, Ruby CE, Albarqi HAM, Taratula O, Bracha S
Translational oncology 2018 Oct;11(5):1137-1146
Translational oncology 2018 Oct;11(5):1137-1146
Enhanced Biosynthesis Performance of Heterologous Proteins in CHO-K1 Cells Using CRISPR-Cas9.
Wang W, Zheng W, Hu F, He X, Wu D, Zhang W, Liu H, Ma X
ACS synthetic biology 2018 May 18;7(5):1259-1268
ACS synthetic biology 2018 May 18;7(5):1259-1268
High expression of QSOX1 is associated with tumor invasiveness and high grades groups in prostate cancer.
Baek JA, Song PH, Ko Y, Gu MJ
Pathology, research and practice 2018 Jul;214(7):964-967
Pathology, research and practice 2018 Jul;214(7):964-967
Reduced QSOX1 enhances radioresistance in nasopharyngeal carcinoma.
Zhou L, Chen HM, Qu S, Li L, Zhao W, Liang ZG, Yu BB, Chen KH, Lu QT, Lin GX, Zhu XD
Oncotarget 2018 Jan 9;9(3):3230-3241
Oncotarget 2018 Jan 9;9(3):3230-3241
QSOX1 expression is associated with aggressive tumor features and reduced survival in breast carcinomas.
Knutsvik G, Collett K, Arnes J, Akslen LA, Stefansson IM
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2016 Dec;29(12):1485-1491
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2016 Dec;29(12):1485-1491
Identification of P-glycoprotein co-fractionating proteins and specific binding partners in rat brain microvessels.
Tome ME, Schaefer CP, Jacobs LM, Zhang Y, Herndon JM, Matty FO, Davis TP
Journal of neurochemistry 2015 Jul;134(2):200-10
Journal of neurochemistry 2015 Jul;134(2):200-10
The emerging role of QSOX1 in cancer.
Lake DF, Faigel DO
Antioxidants & redox signaling 2014 Jul 20;21(3):485-96
Antioxidants & redox signaling 2014 Jul 20;21(3):485-96
Expression of quiescin sulfhydryl oxidase 1 is associated with a highly invasive phenotype and correlates with a poor prognosis in Luminal B breast cancer.
Katchman BA, Ocal IT, Cunliffe HE, Chang YH, Hostetter G, Watanabe A, LoBello J, Lake DF
Breast cancer research : BCR 2013 Mar 28;15(2):R28
Breast cancer research : BCR 2013 Mar 28;15(2):R28
High expression of QSOX1 reduces tumorogenesis, and is associated with a better outcome for breast cancer patients.
Pernodet N, Hermetet F, Adami P, Vejux A, Descotes F, Borg C, Adams M, Pallandre JR, Viennet G, Esnard F, Jouvenot M, Despouy G
Breast cancer research : BCR 2012 Oct 25;14(5):R136
Breast cancer research : BCR 2012 Oct 25;14(5):R136
Vitamin K epoxide reductase contributes to protein disulfide formation and redox homeostasis within the endoplasmic reticulum.
Rutkevich LA, Williams DB
Molecular biology of the cell 2012 Jun;23(11):2017-27
Molecular biology of the cell 2012 Jun;23(11):2017-27
Quiescin sulfhydryl oxidase 1 promotes invasion of pancreatic tumor cells mediated by matrix metalloproteinases.
Katchman BA, Antwi K, Hostetter G, Demeure MJ, Watanabe A, Decker GA, Miller LJ, Von Hoff DD, Lake DF
Molecular cancer research : MCR 2011 Dec;9(12):1621-31
Molecular cancer research : MCR 2011 Dec;9(12):1621-31
Analysis of the plasma peptidome from pancreas cancer patients connects a peptide in plasma to overexpression of the parent protein in tumors.
Antwi K, Hostetter G, Demeure MJ, Katchman BA, Decker GA, Ruiz Y, Sielaff TD, Koep LJ, Lake DF
Journal of proteome research 2009 Oct;8(10):4722-31
Journal of proteome research 2009 Oct;8(10):4722-31
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- SW 1990 cells were subjected to SDS PAGE followed by western blot with 12713-1-AP(QSOX1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The QSOX1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human QSOX1. This antibody recognizes human,mouse,rat antigen. The QSOX1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
