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- Antibody Data
- Antigen structure
- References [16]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 17363-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17363-1-AP, RRID:AB_2239335
- Product name
- ZnT3 antibody
- Antibody type
- Polyclonal
- Description
- ZnT3 antibody (Cat. #17363-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Putative long range mossy fiber sprouting and regional cytochrome c oxidase alteration in the hippocampus of patients with mesial temporal lobe epilepsy.
Synaptic vesicle protein 2A regulates mossy fiber sprouting in a drug-resistant epilepsy rat model via laminin α5/integrin β1.
Estrogen improves sevoflurane-induced cognitive dysfunction by regulating synaptic zinc homeostasis.
SLC30A3 as a Zinc Transporter-Related Biomarker and Potential Therapeutic Target in Alzheimer's Disease.
Ginsenoside Rb1 combined with Lycium barbarum polysaccharide alleviate the Tripterygium wilfordii polyglycoside-induced oligoasthenozoospermia in mice by inhibiting ZnT3-mediated oxidative stress response.
Zinc Attenuates Prostate Hyperplasia and Inflammatory Injury in Obese Rats by Regulating Zinc Homeostasis and Inhibiting the JAK1/STAT3 Pathway.
Genetic deletion of zinc transporter ZnT(3) induces progressive cognitive deficits in mice by impairing dendritic spine plasticity and glucose metabolism.
HB-EGF activates EGFR to induce reactive neural stem cells in the mouse hippocampus after seizures.
Zinc transporter ZnT3/Slc30a3 has a potential role in zinc ion influx in mouse oocytes.
MicroRNA-30a regulates acute cerebral ischemia-induced blood-brain barrier damage through ZnT4/zinc pathway.
Disruption of zinc transporter ZnT3 transcriptional activity and synaptic vesicular zinc in the brain of Huntington's disease transgenic mouse.
MicroRNA-5572 Is a Novel MicroRNA-Regulating SLC30A3 in Sporadic Amyotrophic Lateral Sclerosis.
Protective roles of SLC30A3 against endoplasmic reticulum stress via ERK1/2 activation.
Zinc transporters ZnT3 and ZnT6 are downregulated in the spinal cords of patients with sporadic amyotrophic lateral sclerosis.
Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder.
Altered biometal homeostasis is associated with CLN6 mRNA loss in mouse neuronal ceroid lipofuscinosis.
Tu T, Wan L, Zhang QL, Yang C, Zhou HS, Sun ZP, Long HY, Tang BS, Pan A, Tu E, Wang J, Yang ZQ, Li ZY, Yan XX
Scientific reports 2026 Jan 14;16(1):5232
Scientific reports 2026 Jan 14;16(1):5232
Synaptic vesicle protein 2A regulates mossy fiber sprouting in a drug-resistant epilepsy rat model via laminin α5/integrin β1.
Shi Y, Xu Y, Hu Y, Liu L, Li C, Ren S, Wu G, Wang L
Brain research bulletin 2025 Oct 15;231:111536
Brain research bulletin 2025 Oct 15;231:111536
Estrogen improves sevoflurane-induced cognitive dysfunction by regulating synaptic zinc homeostasis.
Li F, Gong B, Yang T, Long S, Zhang J, Jiang Y, Yu Y, Yang Y, Li D
Molecular medicine (Cambridge, Mass.) 2025 Oct 14;31(1):312
Molecular medicine (Cambridge, Mass.) 2025 Oct 14;31(1):312
SLC30A3 as a Zinc Transporter-Related Biomarker and Potential Therapeutic Target in Alzheimer's Disease.
Bai R, Cheng Z, Diao Y
Genes 2025 Nov 13;16(11)
Genes 2025 Nov 13;16(11)
Ginsenoside Rb1 combined with Lycium barbarum polysaccharide alleviate the Tripterygium wilfordii polyglycoside-induced oligoasthenozoospermia in mice by inhibiting ZnT3-mediated oxidative stress response.
Li X, Ding J, Wang J, He J, Sheng W
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2025 Jun;89:127646
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2025 Jun;89:127646
Zinc Attenuates Prostate Hyperplasia and Inflammatory Injury in Obese Rats by Regulating Zinc Homeostasis and Inhibiting the JAK1/STAT3 Pathway.
Li Y, Wu Z, Ma J, Liu X, Zhang C, Ma J, Li W, Zhao B, Wang S
The Prostate 2025 Jun;85(8):767-776
The Prostate 2025 Jun;85(8):767-776
Genetic deletion of zinc transporter ZnT(3) induces progressive cognitive deficits in mice by impairing dendritic spine plasticity and glucose metabolism.
Zong R, Zhang X, Dong X, Liu G, Zhang J, Gao Y, Zhang Z, Ma Y, Gao H, Gamper N
Frontiers in molecular neuroscience 2024;17:1375925
Frontiers in molecular neuroscience 2024;17:1375925
HB-EGF activates EGFR to induce reactive neural stem cells in the mouse hippocampus after seizures.
Pastor-Alonso O, Durá I, Bernardo-Castro S, Varea E, Muro-García T, Martín-Suárez S, Encinas-Pérez JM, Pineda JR
Life science alliance 2024 Sep;7(9)
Life science alliance 2024 Sep;7(9)
Zinc transporter ZnT3/Slc30a3 has a potential role in zinc ion influx in mouse oocytes.
Kageyama A, Terakawa J, Takarabe S, Sugita H, Kawata Y, Ito J, Kashiwazaki N
The Journal of reproduction and development 2024 Oct 1;70(5):338-342
The Journal of reproduction and development 2024 Oct 1;70(5):338-342
MicroRNA-30a regulates acute cerebral ischemia-induced blood-brain barrier damage through ZnT4/zinc pathway.
Wang P, Pan R, Weaver J, Jia M, Yang X, Yang T, Liang J, Liu KJ
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2021 Mar;41(3):641-655
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2021 Mar;41(3):641-655
Disruption of zinc transporter ZnT3 transcriptional activity and synaptic vesicular zinc in the brain of Huntington's disease transgenic mouse.
Niu L, Li L, Yang S, Wang W, Ye C, Li H
Cell & bioscience 2020;10:106
Cell & bioscience 2020;10:106
MicroRNA-5572 Is a Novel MicroRNA-Regulating SLC30A3 in Sporadic Amyotrophic Lateral Sclerosis.
Kurita H, Yabe S, Ueda T, Inden M, Kakita A, Hozumi I
International journal of molecular sciences 2020 Jun 24;21(12)
International journal of molecular sciences 2020 Jun 24;21(12)
Protective roles of SLC30A3 against endoplasmic reticulum stress via ERK1/2 activation.
Kurita H, Okuda R, Yokoo K, Inden M, Hozumi I
Biochemical and biophysical research communications 2016 Oct 28;479(4):853-859
Biochemical and biophysical research communications 2016 Oct 28;479(4):853-859
Zinc transporters ZnT3 and ZnT6 are downregulated in the spinal cords of patients with sporadic amyotrophic lateral sclerosis.
Kaneko M, Noguchi T, Ikegami S, Sakurai T, Kakita A, Toyoshima Y, Kambe T, Yamada M, Inden M, Hara H, Oyanagi K, Inuzuka T, Takahashi H, Hozumi I
Journal of neuroscience research 2015 Feb;93(2):370-9
Journal of neuroscience research 2015 Feb;93(2):370-9
Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder.
Grubman A, Lidgerwood GE, Duncan C, Bica L, Tan JL, Parker SJ, Caragounis A, Meyerowitz J, Volitakis I, Moujalled D, Liddell JR, Hickey JL, Horne M, Longmuir S, Koistinaho J, Donnelly PS, Crouch PJ, Tammen I, White AR, Kanninen KM
Acta neuropathologica communications 2014 Feb 28;2:25
Acta neuropathologica communications 2014 Feb 28;2:25
Altered biometal homeostasis is associated with CLN6 mRNA loss in mouse neuronal ceroid lipofuscinosis.
Kanninen KM, Grubman A, Caragounis A, Duncan C, Parker SJ, Lidgerwood GE, Volitakis I, Ganio G, Crouch PJ, White AR
Biology open 2013 Jun 15;2(6):635-46
Biology open 2013 Jun 15;2(6):635-46
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 17363-1-AP(SLC30A3 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 17363-1-AP(SLC30A3 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ZnT3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ZnT3. This antibody recognizes human,mouse,rat antigen. The ZnT3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
