26513-1-AP

antibody from Proteintech Group

Targeting: DIO2 SelY, TXDI2

Provider product page for 26513-1-AP

Western blot

ELISA

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [20]
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Product number: 26513-1-AP - Provider product page
Provider: Proteintech Group
Product name: DIO2 antibody
Antibody type: Polyclonal
Description: DIO2 antibody (Cat. #26513-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB,ELISA.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

DIO2 protein structure - 26513-1-AP shown in red.

Submitted references Integration of non-targeted metabolomics and transcriptomics reveals the mechanistic rationale of Coptidis Rhizoma's cold property via systemic energy homeostasis and adaptive thermogenesis in mice.

Xie R, Liu Y, Song Q, Song L, Li J, Zhang Y, Meng J, Dou B, Hu X, Gao L, Zhao Q, Huo H, Sui F
Journal of ethnopharmacology 2026 May 10;362:121344

Bisphenol A increases fat mass in adipose tissue by disturbing gut microbiota-dependent bile acid metabolism and TGR5/UCP1 signaling pathways in CD-1 mice.

Chen X, Zou J, Hong T, Zhang H, Yang J, Mai H, Shi H, Li X, Feng D
Ecotoxicology and environmental safety 2025 Sep 15;303:118922

Triiodothyronine activates THRβ to promote PGC1α expression alleviating PQ-induced pulmonary fibrosis.

Chen W, Geng Z, Luo H, Huang Z, Yang Y, Luo X, Fu B, Liu Z, Fu X
Ecotoxicology and environmental safety 2025 Jan 1;289:117713

Immunization with OPN5 increased seasonal degradation of reproductive activity in Magang ganders.

Pan J, Shen X, Ouyang H, Sun J, Liufu S, Jiang D, Chen W, Peng S, Xu D, Tian Y, Huang Y, He J
Poultry science 2025 Feb;104(2):104753

Curcumin Inhibits Bisphenol A-Induced Fat Mass Gain by Enhancing White Adipose Tissue Browning via Modulating Gut Microbiota-Dependent Bile Acid Metabolism in CD-1 Mice.

Chen X, Zou J, Cao Z, Hong T, Zhang H, Yang J, Mai H, Li X, Feng D
Journal of medicinal food 2025 Dec;28(12):1244-1255

Multi-layered transcriptional control of glycogen metabolism coordinates thermogenic remodeling of white adipocytes in male mice.

Fu H, Lee S, Zemke NR, Fan W, Wang Y, Garza J, Tin D, Villao B, Zhang B, Ma X, Zhang J, Dong T, Ren Y, Downes M, Evans RM, Ren B, Saltiel AR
Nature communications 2025 Dec 16;17(1):809

T3-THR Signaling Governed by DIO2 Contributes to Endometrial Receptivity by Regulating Epithelial Cell Membrane Fluidity.

Zhang R, Peng M, Liu T, Liu X, He J, Mu X, Chen X, Gao R, Wang Y, Wen Y, Geng Y
Endocrinology 2025 Apr 22;166(6)

Exogenous thyroxine increases cardiac GLUT4 translocation in insulin resistant OLETF rats.

Mendez DA, Soñanez-Organis JG, Yang X, Vazquez-Anaya G, Nishiyama A, Ortiz RM
Molecular and cellular endocrinology 2024 Sep 1;590:112254

Glycogen synthesis is required for adaptive thermogenesis in beige adipose tissue and affects diet-induced obesity.

Zhuo S, Bai M, Wang Z, Chen L, Li Z, Zhu X, Chen J, Ye X, Guo C, Chen Y
American journal of physiology. Endocrinology and metabolism 2024 May 1;326(5):E696-E708

Dysregulated Gln-Glu-α-ketoglutarate axis impairs maternal decidualization and increases the risk of recurrent spontaneous miscarriage.

Tang L, Xu XH, Xu S, Liu Z, He Q, Li W, Sun J, Shuai W, Mao J, Zhao JY, Jin L
Cell reports. Medicine 2023 May 16;4(5):101026

T(3) Intratracheal Therapy Alleviates Pulmonary Pathology in an Elastase-Induced Emphysema-Dominant COPD Mouse Model.

Takahashi N, Nakashima R, Nasu A, Hayashi M, Fujikawa H, Kawakami T, Eto Y, Kishimoto T, Fukuyama A, Ogasawara C, Kawano K, Fujiwara Y, Suico MA, Kai H, Shuto T
Antioxidants (Basel, Switzerland) 2023 Dec 22;13(1)

Ribosome stalling during selenoprotein translation exposes a ferroptosis vulnerability.

Li Z, Ferguson L, Deol KK, Roberts MA, Magtanong L, Hendricks JM, Mousa GA, Kilinc S, Schaefer K, Wells JA, Bassik MC, Goga A, Dixon SJ, Ingolia NT, Olzmann JA
Nature chemical biology 2022 Jul;18(7):751-761

Maternal nutrient restriction alters thyroid hormone dynamics in placentae of sheep having small for gestational age fetuses.

Steinhauser CB, Askelson K, Hobbs KC, Bazer FW, Satterfield MC
Domestic animal endocrinology 2021 Oct;77:106632

Exposure to melamine cyanuric acid in adult mice induced thyroid dysfunction and circadian rhythm disorder.

Wang S, Wang S, Wang C, Feng D, Feng X
Ecotoxicology and environmental safety 2021 Nov 19;228:112992

NNT-induced tumor cell "slimming" reverses the pro-carcinogenesis effect of HIF2a in tumors.

Xiong Z, Xiong W, Xiao W, Yuan C, Shi J, Huang Y, Wang C, Meng X, Chen Z, Yang H, Chen K, Zhang X
Clinical and translational medicine 2021 Jan;11(1):e264

Aerosolized Thyroid Hormone Prevents Radiation Induced Lung Fibrosis.

Li L, Nie X, Yi M, Qin W, Li F, Wu B, Yuan X
Frontiers in oncology 2020;10:528686

Tumor Cell "Slimming" Regulates Tumor Progression through PLCL1/UCP1-Mediated Lipid Browning.

Xiong Z, Xiao W, Bao L, Xiong W, Xiao H, Qu Y, Yuan C, Ruan H, Cao Q, Wang K, Song Z, Wang C, Hu W, Ru Z, Tong J, Cheng G, Xu T, Meng X, Shi J, Chen Z, Yang H, Chen K, Zhang X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2019 May 17;6(10):1801862

The tumor secretory factor ZAG promotes white adipose tissue browning and energy wasting.

Elattar S, Dimri M, Satyanarayana A
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Sep;32(9):4727-4743

Knockdown of Trnau1ap inhibits the proliferation and migration of NIH3T3, JEG-3 and Bewo cells via the PI3K/Akt signaling pathway.

Hu X, Luo J, Lai H, Li M, Zheng X, Nie T, Li F, Li H
Biochemical and biophysical research communications 2018 Sep 5;503(2):521-527

Id1 Promotes Obesity by Suppressing Brown Adipose Thermogenesis and White Adipose Browning.

Patil M, Sharma BK, Elattar S, Chang J, Kapil S, Yuan J, Satyanarayana A
Diabetes 2017 Jun;66(6):1611-1625

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