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- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Western blot [1]
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- Product number
- 15949-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15949-1-AP, RRID:AB_2093643
- Product name
- DYNC2LI1 antibody
- Antibody type
- Polyclonal
- Description
- DYNC2LI1 antibody (Cat. #15949-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Roles for CEP170 in cilia function and dynein-2 assembly.
Dynll1 is essential for development and promotes endochondral bone formation by regulating intraflagellar dynein function in primary cilia.
Dynein-2 intermediate chains play crucial but distinct roles in primary cilia formation and function.
Mutations in IFT-A satellite core component genes IFT43 and IFT121 produce short rib polydactyly syndrome with distinctive campomelia.
DYNC2LI1 mutations broaden the clinical spectrum of dynein-2 defects.
Recombinant human cytoplasmic dynein heavy chain 1 and 2: observation of dynein-2 motor activity in vitro.
Weijman JF, Vuolo L, Shak C, Pugnetti A, Mukhopadhyay AG, Hodgson LR, Heesom KJ, Roberts AJ, Stephens DJ
Journal of cell science 2024 Apr 15;137(8)
Journal of cell science 2024 Apr 15;137(8)
Dynll1 is essential for development and promotes endochondral bone formation by regulating intraflagellar dynein function in primary cilia.
King A, Hoch NC, McGregor NE, Sims NA, Smyth IM, Heierhorst J
Human molecular genetics 2019 Aug 1;28(15):2573-2588
Human molecular genetics 2019 Aug 1;28(15):2573-2588
Dynein-2 intermediate chains play crucial but distinct roles in primary cilia formation and function.
Vuolo L, Stevenson NL, Heesom KJ, Stephens DJ
eLife 2018 Oct 16;7
eLife 2018 Oct 16;7
Mutations in IFT-A satellite core component genes IFT43 and IFT121 produce short rib polydactyly syndrome with distinctive campomelia.
Duran I, Taylor SP, Zhang W, Martin J, Qureshi F, Jacques SM, Wallerstein R, Lachman RS, Nickerson DA, Bamshad M, Cohn DH, Krakow D
Cilia 2017;6:7
Cilia 2017;6:7
DYNC2LI1 mutations broaden the clinical spectrum of dynein-2 defects.
Kessler K, Wunderlich I, Uebe S, Falk NS, Gießl A, Brandstätter JH, Popp B, Klinger P, Ekici AB, Sticht H, Dörr HG, Reis A, Roepman R, Seemanová E, Thiel CT
Scientific reports 2015 Jul 1;5:11649
Scientific reports 2015 Jul 1;5:11649
Recombinant human cytoplasmic dynein heavy chain 1 and 2: observation of dynein-2 motor activity in vitro.
Ichikawa M, Watanabe Y, Murayama T, Toyoshima YY
FEBS letters 2011 Aug 4;585(15):2419-23
FEBS letters 2011 Aug 4;585(15):2419-23
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The DYNC2LI1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human DYNC2LI1. This antibody recognizes human, mouse, rat antigen. The DYNC2LI1 antibody has been validated for the following applications: ELISA, WB analysis.
