Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
Reference
Comment
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- Product number
- 15147-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15147-1-AP, RRID:AB_2077081
- Product name
- CEP68 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CEP68 antibody (Cat. #15147-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Prolonged overexpression of PLK4 leads to formation of centriole rosette clusters that are connected via canonical centrosome linker proteins.
The intercentriolar fibers function as docking sites of centriolar satellites for cilia assembly.
Pathogenic LRRK2 regulates centrosome cohesion via Rab10/RILPL1-mediated CDK5RAP2 displacement.
Cep44 functions in centrosome cohesion by stabilizing rootletin.
Human nuclear RNAi-defective 2 (NRDE2) is an essential RNA splicing factor.
CCDC102B functions in centrosome linker assembly and centrosome cohesion.
The Cytoskeletal Adaptor Obscurin-Like 1 Interacts with the Human Papillomavirus 16 (HPV16) Capsid Protein L2 and Is Required for HPV16 Endocytosis.
Ozcan SC, Kalkan BM, Cicek E, Canbaz AA, Acilan C
Scientific reports 2024 Feb 22;14(1):4370
Scientific reports 2024 Feb 22;14(1):4370
The intercentriolar fibers function as docking sites of centriolar satellites for cilia assembly.
Ryu S, Ko D, Shin B, Rhee K
The Journal of cell biology 2024 Apr 1;223(4)
The Journal of cell biology 2024 Apr 1;223(4)
Pathogenic LRRK2 regulates centrosome cohesion via Rab10/RILPL1-mediated CDK5RAP2 displacement.
Fdez E, Madero-Pérez J, Lara Ordóñez AJ, Naaldijk Y, Fasiczka R, Aiastui A, Ruiz-Martínez J, López de Munain A, Cowley SA, Wade-Martins R, Hilfiker S
iScience 2022 Jun 17;25(6):104476
iScience 2022 Jun 17;25(6):104476
Cep44 functions in centrosome cohesion by stabilizing rootletin.
Hossain D, Shih SY, Xiao X, White J, Tsang WY
Journal of cell science 2020 Feb 21;133(4)
Journal of cell science 2020 Feb 21;133(4)
Human nuclear RNAi-defective 2 (NRDE2) is an essential RNA splicing factor.
Jiao AL, Perales R, Umbreit NT, Haswell JR, Piper ME, Adams BD, Pellman D, Kennedy S, Slack FJ
RNA (New York, N.Y.) 2019 Mar;25(3):352-363
RNA (New York, N.Y.) 2019 Mar;25(3):352-363
CCDC102B functions in centrosome linker assembly and centrosome cohesion.
Xia Y, Huang N, Chen Z, Li F, Fan G, Ma D, Chen J, Teng J
Journal of cell science 2018 Dec 3;131(23)
Journal of cell science 2018 Dec 3;131(23)
The Cytoskeletal Adaptor Obscurin-Like 1 Interacts with the Human Papillomavirus 16 (HPV16) Capsid Protein L2 and Is Required for HPV16 Endocytosis.
Wüstenhagen E, Hampe L, Boukhallouk F, Schneider MA, Spoden GA, Negwer I, Koynov K, Kast WM, Florin L
Journal of virology 2016 Dec 1;90(23):10629-10641
Journal of virology 2016 Dec 1;90(23):10629-10641
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 15147-1-AP(CEP68 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using CEP68 antibody 15147-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 15147-1-AP(CEP68 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 15147-1-AP(CEP68 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue