Antibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 10920-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10920-1-AP, RRID:AB_2202239
- Product name
- THOC1 antibody
- Antibody type
- Polyclonal
- Description
- THOC1 antibody (Cat. #10920-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Modulation of cell physiology by bispecific nanobodies enabling changes in the intracellular localization of organelle proteins.
Integrative Analysis Revealed LINC00847 as a Potential Target of Tumor Immunotherapy.
Is Nrf2 Behind Endogenous Neuroprotection of the Hippocampal CA2-4,DG Region?
Downregulation of BASP1 Promotes Temozolomide Resistance in Gliomas via Epigenetic Activation of the FBXO32/NF-κB/MGMT Axis.
PLAGL2 promotes bladder cancer progression via RACGAP1/RhoA GTPase/YAP1 signaling.
LincRNA01703 Facilitates CD81(+) Exosome Secretion to Inhibit Lung Adenocarcinoma Metastasis via the Rab27a/SYTL1/CD81 Complex.
SHFL inhibits enterovirus A71 infection by triggering degradation of viral 3D(pol) protein via the ubiquitin-proteasome pathway.
TREX (transcription/export)-NP complex exerts a dual effect on regulating polymerase activity and replication of influenza A virus.
Cytoplasmic Clusterin Suppresses Lung Cancer Metastasis by Inhibiting the ROCK1-ERK Axis.
Bioactive peptide inhibits acute myeloid leukemia cell proliferation by downregulating ALKBH5-mediated m(6)A demethylation of EIF4EBP1 and MLST8 mRNA.
Diurnal Expression of PD-1 on Tumor-Associated Macrophages Underlies the Dosing Time-Dependent Antitumor Effects of the PD-1/PD-L1 Inhibitor BMS-1 in B16/BL6 Melanoma-Bearing Mice.
Circ_0119872 promotes uveal melanoma development by regulating the miR-622/G3BP1 axis and downstream signalling pathways.
Post-transcriptional repression of circadian component CLOCK regulates cancer-stemness in murine breast cancer cells.
TIMELESS confers cisplatin resistance in nasopharyngeal carcinoma by activating the Wnt/β-catenin signaling pathway and promoting the epithelial mesenchymal transition.
Elevated expression of Thoc1 is associated with aggressive phenotype and poor prognosis in colorectal cancer.
The suppression of thoc1 in cancer cell apoptosis mediated by activated macrophages is nitric oxide-dependent.
Tsuruta A, Kanetani D, Shiiba Y, Inoki T, Yoshida Y, Matsunaga N, Koyanagi S, Ohdo S
Biochemical pharmacology 2023 Sep;215:115708
Biochemical pharmacology 2023 Sep;215:115708
Integrative Analysis Revealed LINC00847 as a Potential Target of Tumor Immunotherapy.
Chen X, Zhang L
Applied biochemistry and biotechnology 2023 Oct;195(10):6345-6358
Applied biochemistry and biotechnology 2023 Oct;195(10):6345-6358
Is Nrf2 Behind Endogenous Neuroprotection of the Hippocampal CA2-4,DG Region?
Lewczuk A, Zablocka B, Beresewicz-Haller M
Molecular neurobiology 2023 Mar;60(3):1645-1658
Molecular neurobiology 2023 Mar;60(3):1645-1658
Downregulation of BASP1 Promotes Temozolomide Resistance in Gliomas via Epigenetic Activation of the FBXO32/NF-κB/MGMT Axis.
Liao X, Li Z, Zheng H, Qian W, Zhang S, Chen S, Li X, Tang M, Xu Y, Yu R, Li M, Song L, Li J
Molecular cancer research : MCR 2023 Jul 5;21(7):648-663
Molecular cancer research : MCR 2023 Jul 5;21(7):648-663
PLAGL2 promotes bladder cancer progression via RACGAP1/RhoA GTPase/YAP1 signaling.
Chen H, Yang W, Li Y, Ji Z
Cell death & disease 2023 Jul 15;14(7):433
Cell death & disease 2023 Jul 15;14(7):433
LincRNA01703 Facilitates CD81(+) Exosome Secretion to Inhibit Lung Adenocarcinoma Metastasis via the Rab27a/SYTL1/CD81 Complex.
Huang Y, Guo S, Lin Y, Huo L, Yan H, Lin Z, Chen Z, Cai J, Wu J, Yuan J, Guan H, Wu G, Wu W, Tao T
Cancers 2023 Dec 9;15(24)
Cancers 2023 Dec 9;15(24)
SHFL inhibits enterovirus A71 infection by triggering degradation of viral 3D(pol) protein via the ubiquitin-proteasome pathway.
Tan C, Qin X, Tan Y, Dong X, Chen D, Liang L, Li J, Niu R, Cao K, He Z, Wei G, Huang M, Zhu X
Journal of medical virology 2023 Aug;95(8):e29030
Journal of medical virology 2023 Aug;95(8):e29030
TREX (transcription/export)-NP complex exerts a dual effect on regulating polymerase activity and replication of influenza A virus.
Zhao L, Liu Q, Huang J, Lu Y, Zhao Y, Ping J
PLoS pathogens 2022 Sep;18(9):e1010835
PLoS pathogens 2022 Sep;18(9):e1010835
Cytoplasmic Clusterin Suppresses Lung Cancer Metastasis by Inhibiting the ROCK1-ERK Axis.
Huang S, Li X, Gu W, Li X, Zhao J, Wu J, Cai J, Feng X, Tao T
Cancers 2022 May 17;14(10)
Cancers 2022 May 17;14(10)
Bioactive peptide inhibits acute myeloid leukemia cell proliferation by downregulating ALKBH5-mediated m(6)A demethylation of EIF4EBP1 and MLST8 mRNA.
Zhang L, Su X
Cellular oncology (Dordrecht, Netherlands) 2022 Jun;45(3):355-365
Cellular oncology (Dordrecht, Netherlands) 2022 Jun;45(3):355-365
Diurnal Expression of PD-1 on Tumor-Associated Macrophages Underlies the Dosing Time-Dependent Antitumor Effects of the PD-1/PD-L1 Inhibitor BMS-1 in B16/BL6 Melanoma-Bearing Mice.
Tsuruta A, Shiiba Y, Matsunaga N, Fujimoto M, Yoshida Y, Koyanagi S, Ohdo S
Molecular cancer research : MCR 2022 Jun 3;20(6):972-982
Molecular cancer research : MCR 2022 Jun 3;20(6):972-982
Circ_0119872 promotes uveal melanoma development by regulating the miR-622/G3BP1 axis and downstream signalling pathways.
Liu S, Chen L, Chen H, Xu K, Peng X, Zhang M
Journal of experimental & clinical cancer research : CR 2021 Feb 12;40(1):66
Journal of experimental & clinical cancer research : CR 2021 Feb 12;40(1):66
Post-transcriptional repression of circadian component CLOCK regulates cancer-stemness in murine breast cancer cells.
Ogino T, Matsunaga N, Tanaka T, Tanihara T, Terajima H, Yoshitane H, Fukada Y, Tsuruta A, Koyanagi S, Ohdo S
eLife 2021 Apr 23;10
eLife 2021 Apr 23;10
TIMELESS confers cisplatin resistance in nasopharyngeal carcinoma by activating the Wnt/β-catenin signaling pathway and promoting the epithelial mesenchymal transition.
Liu SL, Lin HX, Lin CY, Sun XQ, Ye LP, Qiu F, Wen W, Hua X, Wu XQ, Li J, Song LB, Guo L
Cancer letters 2017 Aug 28;402:117-130
Cancer letters 2017 Aug 28;402:117-130
Elevated expression of Thoc1 is associated with aggressive phenotype and poor prognosis in colorectal cancer.
Liu C, Yue B, Yuan C, Zhao S, Fang C, Yu Y, Yan D
Biochemical and biophysical research communications 2015 Dec 4-11;468(1-2):53-8
Biochemical and biophysical research communications 2015 Dec 4-11;468(1-2):53-8
The suppression of thoc1 in cancer cell apoptosis mediated by activated macrophages is nitric oxide-dependent.
Lin YS, Lin CH, Huang LD, Chao T, Kuo CD, Hung LC, Wong FH, Lin CC, Fu SL
Biochemical pharmacology 2013 Jul 15;86(2):242-52
Biochemical pharmacology 2013 Jul 15;86(2):242-52
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 10920-1-AP(THOC1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The THOC1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human THOC1. This antibody recognizes human,mouse,rat antigen. The THOC1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.