MB0166

antibody from Bioworld Technology, Inc
Targeting: SMYD1 BOP, KMT3D, ZMYND22
Provider product page for MB0166

Antibody data

Product number
MB0166 - Provider product page
Provider
Bioworld Technology, Inc
Product name
SMYD1 monoclonal antibody
Antibody type
Monoclonal
Antigen
Recombinant full length Human SMYD1.
Description
SMYD1 (SET and MYND domain-containing protein 1), also known as BOP, ZMYND18 or ZMYND22, is a nuclear and cytoplasmic protein that contains one SET domain and one MYND-type zinc finger. Expressed specifically in cardiac and skeletal muscle, SMYD1 functions as a transcription factor that is essential for cardiac morphogenesis and proper cardiomyocyte differentiation. SMYD1 interacts with the histone deacetylases HDAC1, HDAC2 and HDAC3 and, through this interaction, acts as a histone deacetylase-dependent transcriptional repressor. Defects or deletions in the gene encoding SMYD1 lead to retarded maturation of ventricular cardiomyocytes, further implicating SMYD1 as a crucial component of normal cardiac development.
Reactivity
Rat
Host
Mouse
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SMYD1 protein structure - MB0166 shown in red.