Explore
Validate
Learn
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- HPA039131 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA039131, RRID:AB_10672771
- Product name
- Anti-MYO7B
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human MYO7B, Gene description: myosin VIIB, Validated applications: IHC, Uniprot ID: Q6PIF6, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Organization of a cytoskeletal superstructure in the apical domain of intestinal tuft cells
Defects in microvillus crosslinking sensitize to colitis and inflammatory bowel disease
Myosin 5b is required for proper localization of the intermicrovillar adhesion complex in the intestinal brush border
Comparative analysis of the MyTH4-FERM myosins reveals insights into the determinants of actin track selection in polarized epithelia
A heterologous in-cell assay for investigating intermicrovillar adhesion complex interactions reveals a novel protrusion length-matching mechanism
A cryptic sequence targets the adhesion complex scaffold ANKS4B to apical microvilli to promote enterocyte brush border assembly
The small EF-hand protein CALML4 functions as a critical myosin light chain within the intermicrovillar adhesion complex
Brush border protocadherin CDHR2 promotes the elongation and maximized packing of microvilli in vivo
ANKS4B Is Essential for Intermicrovillar Adhesion Complex Formation
Myosin-7b Promotes Distal Tip Localization of the Intermicrovillar Adhesion Complex
Silverman J, Krystofiak E, Caplan L, Lau K, Tyska M
Journal of Cell Biology 2024;223(12)
Journal of Cell Biology 2024;223(12)
Defects in microvillus crosslinking sensitize to colitis and inflammatory bowel disease
Mödl B, Awad M, Zwolanek D, Scharf I, Schwertner K, Milovanovic D, Moser D, Schmidt K, Pjevac P, Hausmann B, Krauß D, Mohr T, Svinka J, Kenner L, Casanova E, Timelthaler G, Sibilia M, Krieger S, Eferl R
EMBO reports 2023;24(10)
EMBO reports 2023;24(10)
Myosin 5b is required for proper localization of the intermicrovillar adhesion complex in the intestinal brush border
Dooley S, Engevik K, Digrazia J, Stubler R, Kaji I, Krystofiak E, Engevik A
American Journal of Physiology-Gastrointestinal and Liver Physiology 2022;323(5):G501-G510
American Journal of Physiology-Gastrointestinal and Liver Physiology 2022;323(5):G501-G510
Comparative analysis of the MyTH4-FERM myosins reveals insights into the determinants of actin track selection in polarized epithelia
Matoo S, Graves M, Acharya P, Choi M, Storad Z, Idris R, Pickles B, Arvay T, Shinder P, Gerts A, Papish J, Crawley S, Yap A
Molecular Biology of the Cell 2021;32(21)
Molecular Biology of the Cell 2021;32(21)
A heterologous in-cell assay for investigating intermicrovillar adhesion complex interactions reveals a novel protrusion length-matching mechanism
Weck M, Crawley S, Tyska M
Journal of Biological Chemistry 2020;295(48):16191-16206
Journal of Biological Chemistry 2020;295(48):16191-16206
A cryptic sequence targets the adhesion complex scaffold ANKS4B to apical microvilli to promote enterocyte brush border assembly
Graves M, Matoo S, Choi M, Storad Z, El Sheikh Idris R, Pickles B, Acharya P, Shinder P, Arvay T, Crawley S
Journal of Biological Chemistry 2020;295(36):12588-12604
Journal of Biological Chemistry 2020;295(36):12588-12604
The small EF-hand protein CALML4 functions as a critical myosin light chain within the intermicrovillar adhesion complex
Choi M, Graves M, Matoo S, Storad Z, El Sheikh Idris R, Weck M, Smith Z, Tyska M, Crawley S
Journal of Biological Chemistry 2020;295(28):9281-9296
Journal of Biological Chemistry 2020;295(28):9281-9296
Brush border protocadherin CDHR2 promotes the elongation and maximized packing of microvilli in vivo
Pinette J, Mao S, Millis B, Krystofiak E, Faust J, Tyska M, Nusrat A
Molecular Biology of the Cell 2019;30(1):108-118
Molecular Biology of the Cell 2019;30(1):108-118
ANKS4B Is Essential for Intermicrovillar Adhesion Complex Formation
Crawley S, Weck M, Grega-Larson N, Shifrin D, Tyska M
Developmental Cell 2016;36(2):190-200
Developmental Cell 2016;36(2):190-200
Myosin-7b Promotes Distal Tip Localization of the Intermicrovillar Adhesion Complex
Weck M, Crawley S, Stone C, Tyska M
Current Biology 2016;26(20):2717-2728
Current Biology 2016;26(20):2717-2728
No comments: Submit comment
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human duodenum and liver tissues using Anti-MYO7B antibody. Corresponding MYO7B RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
