DPABH-18469

antibody from Creative Diagnostics

Targeting: SCN1A FEB3, GEFSP2, HBSCI, NAC1, Nav1.1, SCN1, SMEI

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

DPABH-18469

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-18469, RRID:AB_2514717

Product name

Rabbit Anti-Human SCN1A Polyclonal antibody

Antibody type

Polyclonal

Description

The vertebrate sodium channel is a voltage-gated ion channel essential for the generation and propagation of action potentials, mainly in nerve and muscle. Voltage-sensitive sodium channels are heteromeric complexes consisting of a large central pore-forming glycosylated alpha subunit, and two smaller auxiliary beta subunits. This gene encodes the large alpha subunit, and mutations in this gene have been associated with several epilepsy, convulsion and migraine disorders. Alternative splicing results in multiple transcript variants. The RefSeq Project has decided to create four representative RefSeq records. Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5 untranslated exons, the exact combination of which have not been experimentally confirmed for the full-length transcript.

Reactivity

Human, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

50 uL