Tissue expression
Cell line expression
Protein structure
NAIP
NLR family apoptosis inhibitory proteinBIRC1, NLRB1
This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Nov 2016]
Top validated antibodies |
|||||
Novus Biologicals | NBP1-77196 | 1 references | Polyclonal |
WB
EL
ICC
IP |
|
antibodies-online | ABIN500306 | 2 references | Polyclonal |
WB
EL
ICC
|
|
Invitrogen Antibodies | PA5-98402 | Polyclonal |
WB
EL
ICC
IHC |
||
Abnova Corporation | PAB12920 | 3 references | Polyclonal |
WB
ICC |
|
Cusabio Biotech Co., Ltd | CSB-PA615662LA01HU | Polyclonal |
WB
EL
ICC
IHC |
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider