HPA003446

antibody from Atlas Antibodies

Targeting: SHANK3 KIAA1650, prosap2, PSAP2, SPANK-2

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA003446

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA003446, RRID:AB_1079958

Product name

Anti-SHANK3

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human SHANK3, Gene description: SH3 and multiple ankyrin repeat domains 3, Alternative Gene Names: KIAA1650, prosap2, PSAP2, SPANK-2, Validated applications: IHC, Uniprot ID: , Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

SHANK3 depletion leads to ERK signalling overdose and cell death in KRAS-mutant cancers.

Lilja J, Kaivola J, Conway JRW, Vuorio J, Parkkola H, Roivas P, Dibus M, Chastney MR, Varila T, Jacquemet G, Peuhu E, Wang E, Pentikäinen U, Martinez D Posada I, Hamidi H, Najumudeen AK, Sansom OJ, Barsukov IL, Abankwa D, Vattulainen I, Salmi M, Ivaska J
Nature communications 2024 Sep 12;15(1):8002

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The K63 deubiquitinase CYLD modulates autism-like behaviors and hippocampal plasticity by regulating autophagy and mTOR signaling

Colombo E, Horta G, Roesler M, Ihbe N, Chhabra S, Radyushkin K, Di Liberto G, Kreutzfeldt M, Schumann S, von Engelhardt J, Merkler D, Behl C, Mittmann T, Clement A, Waisman A, Schmeisser M
Proceedings of the National Academy of Sciences 2021;118(47)