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Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 15118-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15118-1-AP, RRID:AB_2114848
- Product name
- HCCS antibody
- Antibody type
- Polyclonal
- Description
- HCCS antibody (Cat. #15118-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Biallelic variants in COX18 cause a mitochondrial disorder primarily manifesting as peripheral neuropathy.
FAM136A depletion induces mitochondrial stress and reduces mitochondrial membrane potential and ATP production.
Biallelic variants in COX18 cause a mitochondrial disorder primarily manifesting as peripheral neuropathy.
Reactive oxygen species control protein degradation at the mitochondrial import gate.
Small heat shock proteins operate as molecular chaperones in the mitochondrial intermembrane space.
The Novel Synthetic Triterpene Methyl 3β-O-[4-(2-Aminoethylamino)-4-oxo-butyryl]olean-12-ene-28-oate Inhibits Breast Tumor Cell Growth in Vitro and in Vivo.
SLC25A46 is required for mitochondrial lipid homeostasis and cristae maintenance and is responsible for Leigh syndrome.
Armirola-Ricaurte C, Morant L, Adant I, Hamed SA, Pipis M, Efthymiou S, Amor-Barris S, Atkinson D, Van de Vondel L, Tomic A, Seneca S, de Vriendt E, Zuchner S, Ghesquiere B, Hanna MG, Houlden H, Lunn MP, Reilly MM, Milic Rasic V, Jordanova A
Brain : a journal of neurology 2026 Jan 8;149(1):178-193
Brain : a journal of neurology 2026 Jan 8;149(1):178-193
FAM136A depletion induces mitochondrial stress and reduces mitochondrial membrane potential and ATP production.
Otsuka Y, Yano M
FEBS open bio 2025 May;15(5):738-753
FEBS open bio 2025 May;15(5):738-753
Biallelic variants in COX18 cause a mitochondrial disorder primarily manifesting as peripheral neuropathy.
Armirola-Ricaurte C, Morant L, Adant I, Hamed SA, Pipis M, Efthymiou S, Amor-Barris S, Atkinson D, Van de Vondel L, Tomic A, de Vriendt E, Zuchner S, Ghesquiere B, Hanna M, Houlden H, Lunn MP, Reilly MM, Rasic VM, Jordanova A
medRxiv : the preprint server for health sciences 2024 Jul 4;
medRxiv : the preprint server for health sciences 2024 Jul 4;
Reactive oxygen species control protein degradation at the mitochondrial import gate.
McMinimy R, Manford AG, Gee CL, Chandrasekhar S, Mousa GA, Chuang J, Phu L, Shih KY, Rose CM, Kuriyan J, Bingol B, Rapé M
Molecular cell 2024 Dec 5;84(23):4612-4628.e13
Molecular cell 2024 Dec 5;84(23):4612-4628.e13
Small heat shock proteins operate as molecular chaperones in the mitochondrial intermembrane space.
Adriaenssens E, Asselbergh B, Rivera-Mejías P, Bervoets S, Vendredy L, De Winter V, Spaas K, de Rycke R, van Isterdael G, Impens F, Langer T, Timmerman V
Nature cell biology 2023 Mar;25(3):467-480
Nature cell biology 2023 Mar;25(3):467-480
The Novel Synthetic Triterpene Methyl 3β-O-[4-(2-Aminoethylamino)-4-oxo-butyryl]olean-12-ene-28-oate Inhibits Breast Tumor Cell Growth in Vitro and in Vivo.
Feng B, Zhao C, Li J, Yu J, Zhang Y, Zhang X, Tian T, Zhao L
Chemical & pharmaceutical bulletin 2020;68(10):962-970
Chemical & pharmaceutical bulletin 2020;68(10):962-970
SLC25A46 is required for mitochondrial lipid homeostasis and cristae maintenance and is responsible for Leigh syndrome.
Janer A, Prudent J, Paupe V, Fahiminiya S, Majewski J, Sgarioto N, Des Rosiers C, Forest A, Lin ZY, Gingras AC, Mitchell G, McBride HM, Shoubridge EA
EMBO molecular medicine 2016 Sep;8(9):1019-38
EMBO molecular medicine 2016 Sep;8(9):1019-38
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human heart tissue were subjected to SDS PAGE followed by western blot with 15118-1-AP(HCCS antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 15118-1-AP(HCCS antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HCCS antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HCCS. This antibody recognizes human,mouse,rat antigen. The HCCS antibody has been validated for the following applications: ELISA, WB, IHC analysis.
