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Learn18336-1-AP
antibody from Proteintech Group
Targeting: LSM14A
C19orf13, DKFZP434D1335, FAM61A, RAP55, RAP55A
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [20]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 18336-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18336-1-AP, RRID:AB_10644339
- Product name
- LSM14A antibody
- Antibody type
- Polyclonal
- Description
- LSM14A antibody (Cat. #18336-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references FBXW7 Targets the SPT6-ΔNp63 Axis for Degradation to Inhibit Esophageal Tumorigenesis Induced by 4-Nitroquinoline N-Oxide.
Differential assembly of RNP granules via activation of distinct dsRNA sensors by adenovirus mutants.
NSCLC cells sustain phase separation of cytoplasmic membrane-less organelles to protect themselves against cisplatin treatment.
The molecular axis hnRNPU/circKCNK2/EDC4/IL-11 aggravates osteolytic bone metastasis of RCC.
FTO-mediated m(6)A demethylation regulates IGFBP3 expression and AKT activation through IMP3-dependent P-body re-localisation in lung cancer.
Time-series single-cell transcriptomic profiling of luteal-phase endometrium uncovers dynamic characteristics and its dysregulation in recurrent implantation failures.
CCHCR1 links P-body proteins to the centrosome and is required for ciliogenesis through interacting with OFD1 and PCM1.
RNA sequestration in P-bodies sustains myeloid leukaemia.
TIRR regulates mRNA export and association with P-bodies in response to DNA damage.
Pooled CRISPR Screening Identifies P-Bodies as Repressors of Cancer Epithelial-Mesenchymal Transition.
DDX6 modulates P-body and stress granule assembly, composition, and docking.
Energy stress promotes P-bodies formation via lysine-63-linked polyubiquitination of HAX1.
YAP/TAZ enhances P-body formation to promote tumorigenesis.
Identification of the proteolytic signature in CVB3-infected cells.
METTL1-modulated LSM14A facilitates proliferation and migration in glioblastoma via the stabilization of DDX5.
The divergent effects of G3BP orthologs on human stress granule assembly imply a centric role for the core protein interaction network.
RNA helicase DDX6 and scaffold protein GW182 in P-bodies promote biogenesis of stress granules.
Oleic Acid Dissolves cGAS-DNA Phase Separation to Inhibit Immune Surveillance.
The proteome and transcriptome of stress granules and P bodies during human T lymphocyte activation.
Selective sorting of microRNAs into exosomes by phase-separated YBX1 condensates.
Zhang J, Yin L, You X, Xiong X, Sun Y
MedComm 2026 Mar;7(3):e70662
MedComm 2026 Mar;7(3):e70662
Differential assembly of RNP granules via activation of distinct dsRNA sensors by adenovirus mutants.
Steinbock RT, Scudero OB, Dybas JM, Abbott ARN, Kulej K, Lauman R, Chan H, Agostino EL, Kumar N, Briggs S, Parenti NA, Li Y, Burke JM, Weiss SR, Price AM, Weitzman MD
bioRxiv : the preprint server for biology 2026 Feb 18;
bioRxiv : the preprint server for biology 2026 Feb 18;
NSCLC cells sustain phase separation of cytoplasmic membrane-less organelles to protect themselves against cisplatin treatment.
Li NN, Rao LL, Su D, Liu BH, Ma GQ, Wang HF, Zhang ZL, Ying Z
Acta pharmacologica Sinica 2025 Sep;46(9):2522-2533
Acta pharmacologica Sinica 2025 Sep;46(9):2522-2533
The molecular axis hnRNPU/circKCNK2/EDC4/IL-11 aggravates osteolytic bone metastasis of RCC.
Wang Y, Zhao D, Lu J, Hou N, Wu Q, Zhou S, Xu J, Xue W, Cui W, Zheng J, Wang F, Zhai W
Oncogene 2025 Sep;44(36):3310-3332
Oncogene 2025 Sep;44(36):3310-3332
FTO-mediated m(6)A demethylation regulates IGFBP3 expression and AKT activation through IMP3-dependent P-body re-localisation in lung cancer.
Wang H, Peng H, Zhang Z, Abulimiti Y, Hu J, Zhou Y, Ji P, Li D
Clinical and translational medicine 2025 Jul;15(7):e70392
Clinical and translational medicine 2025 Jul;15(7):e70392
Time-series single-cell transcriptomic profiling of luteal-phase endometrium uncovers dynamic characteristics and its dysregulation in recurrent implantation failures.
Cao D, Liu Y, Cheng Y, Wang J, Zhang B, Zhai Y, Zhu K, Liu Y, Shang Y, Xiao X, Chang Y, Lee YL, Yeung WSB, Huang Y, Yao Y
Nature communications 2025 Jan 2;16(1):137
Nature communications 2025 Jan 2;16(1):137
CCHCR1 links P-body proteins to the centrosome and is required for ciliogenesis through interacting with OFD1 and PCM1.
Zhang J, Wu Q, Zhang S, Sze SCW, Li C
Cellular & molecular biology letters 2025 Aug 29;30(1):103
Cellular & molecular biology letters 2025 Aug 29;30(1):103
RNA sequestration in P-bodies sustains myeloid leukaemia.
Kodali S, Proietti L, Valcarcel G, López-Rubio AV, Pessina P, Eder T, Shi J, Jen A, Lupión-Garcia N, Starner AC, Bartels MD, Cui Y, Sands CM, Planas-Riverola A, Martínez A, Velasco-Hernandez T, Tomás-Daza L, Alber B, Manhart G, Mayer IM, Kollmann K, Fatica A, Menendez P, Shishkova E, Rau RE, Javierre BM, Coon J, Chen Q, Van Nostrand EL, Sardina JL, Grebien F, Di Stefano B
Nature cell biology 2024 Oct;26(10):1745-1758
Nature cell biology 2024 Oct;26(10):1745-1758
TIRR regulates mRNA export and association with P-bodies in response to DNA damage.
Glossop MS, Chelysheva I, Ketley RF, Alagia A, Gullerova M
Nucleic acids research 2024 Nov 11;52(20):12633-12649
Nucleic acids research 2024 Nov 11;52(20):12633-12649
Pooled CRISPR Screening Identifies P-Bodies as Repressors of Cancer Epithelial-Mesenchymal Transition.
Fang L, Zhang L, Wang M, He Y, Yang J, Huang Z, Tan Y, Fang K, Li J, Sun Z, Li Y, Tang Y, Liang W, Cui H, Zhu Q, Wu Z, Li Y, Hu Y, Chen W
Cancer research 2024 Mar 4;84(5):659-674
Cancer research 2024 Mar 4;84(5):659-674
DDX6 modulates P-body and stress granule assembly, composition, and docking.
Ripin N, Macedo de Vasconcelos L, Ugay DA, Parker R
The Journal of cell biology 2024 Jun 3;223(6)
The Journal of cell biology 2024 Jun 3;223(6)
Energy stress promotes P-bodies formation via lysine-63-linked polyubiquitination of HAX1.
Zhan W, Li Z, Zhang J, Liu Y, Liu G, Li B, Shen R, Jiang Y, Shang W, Gao S, Wu H, Wang Y, Chen W, Wang Z
The EMBO journal 2024 Jul;43(13):2759-2788
The EMBO journal 2024 Jul;43(13):2759-2788
YAP/TAZ enhances P-body formation to promote tumorigenesis.
Shen X, Peng X, Guo Y, Dai Z, Cui L, Yu W, Liu Y, Liu CY
eLife 2024 Jul 24;12
eLife 2024 Jul 24;12
Identification of the proteolytic signature in CVB3-infected cells.
Vlok M, Solis N, Sadasivan J, Mohamud Y, Warsaba R, Kizhakkedathu J, Luo H, Overall CM, Jan E
Journal of virology 2024 Jul 23;98(7):e0049824
Journal of virology 2024 Jul 23;98(7):e0049824
METTL1-modulated LSM14A facilitates proliferation and migration in glioblastoma via the stabilization of DDX5.
Wang C, He Y, Fang X, Zhang D, Huang J, Zhao S, Li L, Li G
iScience 2024 Jul 19;27(7):110225
iScience 2024 Jul 19;27(7):110225
The divergent effects of G3BP orthologs on human stress granule assembly imply a centric role for the core protein interaction network.
Yao Z, Liu Y, Chen Q, Chen X, Zhu Z, Song S, Ma X, Yang P
Cell reports 2024 Aug 27;43(8):114617
Cell reports 2024 Aug 27;43(8):114617
RNA helicase DDX6 and scaffold protein GW182 in P-bodies promote biogenesis of stress granules.
Majerciak V, Zhou T, Kruhlak MJ, Zheng ZM
Nucleic acids research 2023 Sep 22;51(17):9337-9355
Nucleic acids research 2023 Sep 22;51(17):9337-9355
Oleic Acid Dissolves cGAS-DNA Phase Separation to Inhibit Immune Surveillance.
Wang L, Liu Q, Wang N, Li S, Bian W, Sun Z, Wang L, Wang L, Liu C, Song C, Liu Q, Yang Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 May;10(14):e2206820
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 May;10(14):e2206820
The proteome and transcriptome of stress granules and P bodies during human T lymphocyte activation.
Curdy N, Lanvin O, Cerapio JP, Pont F, Tosolini M, Sarot E, Valle C, Saint-Laurent N, Lhuillier E, Laurent C, Fournié JJ, Franchini DM
Cell reports 2023 Mar 28;42(3):112211
Cell reports 2023 Mar 28;42(3):112211
Selective sorting of microRNAs into exosomes by phase-separated YBX1 condensates.
Liu XM, Ma L, Schekman R
eLife 2021 Nov 12;10
eLife 2021 Nov 12;10
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 18336-1-AP(LSM14A antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 18336-1-AP(LSM14A antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The LSM14A antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human LSM14A. This antibody recognizes human, mouse, rat antigen. The LSM14A antibody has been validated for the following applications: ELISA, WB, IHC analysis.
