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antibody from Boster Biological Technology
Targeting: FOXP3
AIID, DIETER, IPEX, JM2, PIDX, SCURFIN, XPID
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- RP1032 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-Forkhead box protein P3 FOXP3 Antibody
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for FOXP3 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. FOXP3 information: Molecular Weight: 47244 MW; Subcellular Localization: Nucleus . Cytoplasm . Predominantly expressed in the cytoplasm in activated conventional T-cells whereas predominantly expressed in the nucleus in regulatory T-cells (Treg). The 41 kDa form derived by proteolytic processing is found exclusively in the chromatin fraction of activated Treg cells (By similarity).
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 100μg/vial
- Concentration
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Handling
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Submitted references Marsdenia tenacissima enhances immune response of tumor infiltrating T lymphocytes to colorectal cancer.
Regulatory T cells promote functional recovery after spinal cord injury by alleviating microglia inflammation via STAT3 inhibition.
Manipulating adrenergic stress receptor signalling to enhance immunosuppression and prolong survival of vascularized composite tissue transplants.
Prognosis significance of indoleamine 2, 3-dioxygenase, programmed death ligand-1 and tumor-infiltrating immune cells in microenvironment of breast cancer.
Effect of compound sophorae decoction on dextran sodium sulfate (DSS)-induced colitis in mice by regulating Th17/Treg cell balance.
Fibroblast activation proteins-α suppress tumor immunity by regulating T cells and tumor-associated macrophages.
Inhibition of microRNA-155 attenuates concanavalin-A-induced autoimmune hepatitis by regulating Treg/Th17 cell differentiation.
Impaired TNF/TNFR2 signaling enhances Th2 and Th17 polarization and aggravates allergic airway inflammation.
IL-35 improves T(reg)-mediated immune suppression in atherosclerotic mice.
T2 enhances in situ level of Foxp3+ regulatory cells and modulates inflammatory cytokines in Crohn's disease.
Potential role of plasmacytoid dendritic cells for FOXP3+ regulatory T cell development in human colorectal cancer and tumor draining lymph node.
Yi B, Zhang S, Yan S, Liu Y, Feng Z, Chu T, Liu J, Wang W, Xue J, Zhang C, Wang Y
Frontiers in immunology 2023;14:1238694
Frontiers in immunology 2023;14:1238694
Regulatory T cells promote functional recovery after spinal cord injury by alleviating microglia inflammation via STAT3 inhibition.
Liu R, Li Y, Wang Z, Chen P, Xie Y, Qu W, Wang M, Yu Z, Luo X
CNS neuroscience & therapeutics 2023 Aug;29(8):2129-2144
CNS neuroscience & therapeutics 2023 Aug;29(8):2129-2144
Manipulating adrenergic stress receptor signalling to enhance immunosuppression and prolong survival of vascularized composite tissue transplants.
Kim M, Fisher DT, Bogner PN, Sharma U, Yu H, Skitzki JJ, Repasky EA
Clinical and translational medicine 2022 Aug;12(8):e996
Clinical and translational medicine 2022 Aug;12(8):e996
Prognosis significance of indoleamine 2, 3-dioxygenase, programmed death ligand-1 and tumor-infiltrating immune cells in microenvironment of breast cancer.
Wei L, Wu N, Wei F, Li F, Zhang Y, Liu J, Ren X
International immunopharmacology 2020 Jul;84:106506
International immunopharmacology 2020 Jul;84:106506
Effect of compound sophorae decoction on dextran sodium sulfate (DSS)-induced colitis in mice by regulating Th17/Treg cell balance.
Xu M, Duan XY, Chen QY, Fan H, Hong ZC, Deng SJ, Nan Z, Wu H, Dong YL, Liu YJ, Zhou CZ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:2396-2408
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:2396-2408
Fibroblast activation proteins-α suppress tumor immunity by regulating T cells and tumor-associated macrophages.
Hou CM, Qu XM, Zhang J, Ding TT, Han W, Ji GC, Zhong ZH, Chen H, Zhang F
Experimental and molecular pathology 2018 Feb;104(1):29-37
Experimental and molecular pathology 2018 Feb;104(1):29-37
Inhibition of microRNA-155 attenuates concanavalin-A-induced autoimmune hepatitis by regulating Treg/Th17 cell differentiation.
Xia G, Wu S, Wang X, Fu M
Canadian journal of physiology and pharmacology 2018 Dec;96(12):1293-1300
Canadian journal of physiology and pharmacology 2018 Dec;96(12):1293-1300
Impaired TNF/TNFR2 signaling enhances Th2 and Th17 polarization and aggravates allergic airway inflammation.
Li XM, Chen X, Gu W, Guo YJ, Cheng Y, Peng J, Guo XJ
American journal of physiology. Lung cellular and molecular physiology 2017 Sep 1;313(3):L592-L601
American journal of physiology. Lung cellular and molecular physiology 2017 Sep 1;313(3):L592-L601
IL-35 improves T(reg)-mediated immune suppression in atherosclerotic mice.
Tao L, Zhu J, Chen Y, Wang Q, Pan Y, Yu Q, Zhou B, Zhu H
Experimental and therapeutic medicine 2016 Oct;12(4):2469-2476
Experimental and therapeutic medicine 2016 Oct;12(4):2469-2476
T2 enhances in situ level of Foxp3+ regulatory cells and modulates inflammatory cytokines in Crohn's disease.
Li G, Ren J, Wang G, Gu G, Hu D, Ren H, Hong Z, Wu X, Liu S, Li J
International immunopharmacology 2014 Feb;18(2):244-8
International immunopharmacology 2014 Feb;18(2):244-8
Potential role of plasmacytoid dendritic cells for FOXP3+ regulatory T cell development in human colorectal cancer and tumor draining lymph node.
Gai XD, Song Y, Li C, Lei YM, Yang B
Pathology, research and practice 2013 Dec;209(12):774-8
Pathology, research and practice 2013 Dec;209(12):774-8
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Supportive validation
- Submitted by
- Boster Biological Technology (provider)
- Main image
- Experimental details
- Anti-FOXP3 Picoband antibody, RP1032-1.JPGIHC(P): Human Tonsil Tissue
- Additional image
