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LearnHPA045943
antibody from Atlas Antibodies
Targeting: FOXP3
AIID, DIETER, IPEX, JM2, PIDX, SCURFIN, XPID
Western blot
Chromatin ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [1]
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- Validations
- Chromatin Immunoprecipitation [1]
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- Product number
- HPA045943 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA045943, RRID:AB_2679508
- Product name
- Anti-FOXP3
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human FOXP3, Gene description: forkhead box P3, Alternative Gene Names: AIID, DIETER, IPEX, JM2, PIDX, SCURFIN, XPID, Validated applications: ICC, ChIP, WB, Uniprot ID: Q9BZS1, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Treg-selective IL-2 starvation synergizes with CD40 activation to sustain durable responses in lymphoma models
Stirm K, Leary P, Wüst D, Stark D, Joller N, Karakus U, Boyman O, Tzankov A, Müller A
Journal for ImmunoTherapy of Cancer 2023;11(2):e006263
Journal for ImmunoTherapy of Cancer 2023;11(2):e006263
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- ChIP-Exo-Seq composite graph for Anti-FOXP3 (HPA045943, Lot 000025871) tested in K562 cells. Strand-specific reads (blue: forward, red: reverse) and IgG controls (black: forward, grey: reverse) are plotted against the distance from a composite set of reference binding sites. The antibody exhibits robust target enrichment compared to a non-specific IgG control and precisely reveals its structural organization around the binding site. Data generated by Prof. B. F. Pugh´s Lab at Cornell University.
