PAB12426
antibody from Abnova Corporation
Targeting: FOXP3
AIID, DIETER, IPEX, JM2, PIDX, SCURFIN, XPID
Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- PAB12426 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB12426, RRID:AB_10549641
- Product name
- FOXP3 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of FOXP3.
- Storage
- Store at 4°C. Do not freeze.
Submitted references Treg-mediated immunosuppression involves activation of the Notch-HES1 axis by membrane-bound TGF-beta.
Lymph node occupancy is required for the peripheral development of alloantigen-specific Foxp3+ regulatory T cells.
Cutting edge: estrogen drives expansion of the CD4+CD25+ regulatory T cell compartment.
Ostroukhova M, Qi Z, Oriss TB, Dixon-McCarthy B, Ray P, Ray A
The Journal of clinical investigation 2006 Apr;116(4):996-1004
The Journal of clinical investigation 2006 Apr;116(4):996-1004
Lymph node occupancy is required for the peripheral development of alloantigen-specific Foxp3+ regulatory T cells.
Ochando JC, Yopp AC, Yang Y, Garin A, Li Y, Boros P, Llodra J, Ding Y, Lira SA, Krieger NR, Bromberg JS
Journal of immunology (Baltimore, Md. : 1950) 2005 Jun 1;174(11):6993-7005
Journal of immunology (Baltimore, Md. : 1950) 2005 Jun 1;174(11):6993-7005
Cutting edge: estrogen drives expansion of the CD4+CD25+ regulatory T cell compartment.
Polanczyk MJ, Carson BD, Subramanian S, Afentoulis M, Vandenbark AA, Ziegler SF, Offner H
Journal of immunology (Baltimore, Md. : 1950) 2004 Aug 15;173(4):2227-30
Journal of immunology (Baltimore, Md. : 1950) 2004 Aug 15;173(4):2227-30
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of human FOXP3 using FOXP3 polyclonal antibody (Cat # PAB12426). Lane 1 : Human CD4+CD25+ PBL, lane 2 : HEK293T transfected with human Foxp3 cDNA, lane 3 : 293/mouse foxp3, lane 4 : 293/empty vector.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Staining of FOXP3 on Healthy thymus from a C57BL/6 mouse using FOXP3 polyclonal antibody (Cat # PAB12426).
- Validation comment
- Immunohistochemistry