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Learn22228-1-AP
antibody from Proteintech Group
Targeting: FOXP3
AIID, DIETER, IPEX, JM2, PIDX, SCURFIN, XPID
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ELISAAntibody data
- Antibody Data
- Antigen structure
- References [117]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
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- Product number
- 22228-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#22228-1-AP, RRID:AB_11182376
- Product name
- FOXP3 antibody
- Antibody type
- Polyclonal
- Description
- FOXP3 antibody (Cat. #22228-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Exosomal lncRNA FENDRR Orchestrates Immune Remodelling and Ferroptosis in the Comorbidity of Lung Cancer and Type 1 Myocardial Infarction.
Danggui Shaoyao San ameliorates neuroinflammation in a D-galactose-induced Alzheimer's disease rat model by suppressing the JAK2/STAT3 pathway and modulating Th17/Treg -related immune dysregulation.
LIFUS-driven engineered bacteria reprogram immunosuppressive niches via mechano-NOTCH signaling.
TONSL promotes hepatocellular carcinoma progression and radioresistance by orchestrating DNA damage repair and cell cycle dynamics.
Diallyl Trisulfide Suppresses Tumor-Associated Macrophage M2-Like Polarization and Recruitment and Improves the Tumor Microenvironment Through Blocking CCL5/STAT3 Signaling Pathway Against Lung Cancer.
Curcumin inhibits HIV-1 by modulating FOXP3 and suppressing CCR5 via PI3K/AKT and JAK/STAT pathways.
SIGLEC15 modulates the immunosuppressive microenvironment and suppresses malignant phenotypes in triple-negative breast cancer.
STT3A-mediated FCN3 N-glycosylation promotes Treg cell activation to drive hepatocellular carcinoma progression via Wnt/β-catenin.
Prediction of tumor-infiltrating lymphocytes through habitat radiomics and exploration of response mechanisms in neoadjuvant immunochemotherapy-treated lung cancer.
TRIP13 promotes the expansion and immunosuppression of CD4(+)Foxp3(+) regulatory T cells by sustaining HAT1 stability.
BMP9 potentiates immunotherapy in triple-negative breast cancer by suppressing Tregs infiltration via the PRKDC-CCL2 axis.
LDRT combined with anti-PD-1 promotes tumor regression in head and neck squamous cell carcinoma through tumor metaprogram evolution and immune cell reprogramming.
TSP-1-CD47-integrin α4β1 axis drives T cell infiltration and synovial inflammation in rheumatoid arthritis.
The expression of autophagy-related gene CXCL12 in endometriosis associated ovarian cancer and pan-cancer analysis.
Fecal Microbiota Transplantation Modulates Th17/Treg Balance via JAK/STAT Pathway in ARDS Rats.
The Paeonol of Total Glucosides of White Peony Regulates the Differentiation of CD4+Treg Cells through the EP300/Foxp3 Axis to Relieve Pulmonary Fibrosis in Mice.
PCV2 infection induces the differentiation of Treg cells via the TGF-β/Smad3 pathway.
Lactiplantibacillus plantarum BD7807 ameliorates high-fat diet-induced lipid metabolic disorders and intestinal dysfunction via SCFAs-GPR43 pathway.
Study on the regulation of Treg cell infiltration by EZH2 through CXCR4/CXCL12 in diffuse large B-cell lymphoma.
MeCP2 attenuates inflammation and regulates T cell phenotype via SFRP4 suppression in preeclampsia.
MiR-519d-3p from Placenta-Derived Exosomes Induce Immune Intolerance Regulating Immune Cells, Contributing to the Pathogenesis of Preeclampsia.
Foxp3 inhibits PCV2 replication by reducing the ATPase activity of Rep.
Phlorizin attenuates lupus nephritis via upregulating PI3K/Akt pathway-mediated Treg differentiation.
L-Kynurenine regulates immune response in ICIs-associated myocarditis via JAK/STAT pathway.
Cryo-trojan mesenchymal stem cells as non-living tumor-homing supercarriers for enhanced drug delivery and immune activation in prostate cancer.
The effect of vitamin C on the JAK/STAT3 pathway in ischemic stroke: based on the molecular interaction between FOXP3 protein and stat3 protein.
Andrographolide and its sulfated metabolite alleviated DSS-induced inflammatory bowel disease through regulating inflammation and immune via MAPK/NLRP3 pathways and the balance of Th17/Treg cells.
Protective effects of polysaccharide of Atractylodes macrocephala Koidz and Jiawei Si-jun-zi Decoction on gut health and immune function in cyclophosphamide-treated chicks.
Effect of RAS mutations and related immune characteristics on the prognosis of patients with MSI-H/dMMR colorectal cancer.
Porcine decellularized splenic matrix hydrogel-based vesicle sustained-release System: A dual-regulatory biomaterial for accelerated wound healing via angiogenesis and immune remodeling.
FOXP3-activated KCNMB2-AS1 promotes clear cell renal cell carcinoma through the miR-744-3p/CD1D axis.
Akkermansia Muciniphila Alleviates Severe Acute Pancreatitis via Amuc1409-Ube2k-Foxp3 Axis in Regulatory T Cells.
Thalidomide mitigates Crohn's disease colitis by modulating gut microbiota, metabolites, and regulatory T cell immunity.
Remodeling of Effector and Regulatory T Cells by Capture and Utilization of miRNAs Using Nanocomposite Hydrogel for Tumor-Specific Photothermal Immunotherapy.
Integrating bulk, single-cell, and spatial transcriptomics to identify and functionally validate novel targets to enhance immunotherapy in NSCLC.
Curcumin chitosan microspheres regulate Th17/Treg balance via IGF2BP1- mediated m6A modification of LRP5 in ulcerative colitis.
Signals from intestinal microbiota mediate the crosstalk between the lung-gut axis in an influenza infection mouse model.
Beneficial effects of Dendrobium officinale National Herbal Drink on metabolic immune crosstalk via regulate SCFAs-Th17/Treg.
Turning to immunosuppressive tumors: Deciphering the immunosenescence-related microenvironment and prognostic characteristics in pancreatic cancer, in which GLUT1 contributes to gemcitabine resistance.
Bergapten enhances mitophagy to regulate intestinal barrier and Th17/Treg balance in mice with Crohn's disease-like colitis via PPARγ/NF-κB signaling pathway.
Investigating the mechanism of METTL16-dependent m6A modification regulating the SAMD11 protein signaling pathway to inhibit thyroid cancer phenotypes.
RSPO3 regulates the radioresistance of Non-Small cell lung cancer cells via NLRP3 Inflammasome-Mediated pyroptosis.
Targeting delivery of mifepristone to endometrial dysfunctional macrophages for endometriosis therapy.
Aucklandiae radix targeted PKM2 to alleviate ulcerative colitis: Insights from the photocrosslinking target fishing technique.
Rhomboid-like 2 correlated with TME infiltration inhibits cuproptosis-related genes and drives malignant phenotype in clear cell renal cell carcinoma.
Tanshinone IIA potentiates the therapeutic efficacy of glucocorticoids in lipopolysaccharide-treated HEI-OC1 cells through modulation of the FOXP3/Nrf2 signaling pathway.
Expression landscape of cancer-FOXP3 and its prognostic value in pancreatic adenocarcinoma.
Fatostatin promotes anti-tumor immunity by reducing SREBP2 mediated cholesterol metabolism in tumor-infiltrating T lymphocytes.
Efficacy and Mechanism of the Action of Live and Heat-Killed Bacillus coagulans BC198 as Potential Probiotic in Ameliorating Dextran Sulfate Sodium-Induced Colitis in Mice.
ROS-responsive drug-releasing injectable microgels for ameliorating myocardial infarction.
Significance of CD10 for Mucosal Immunomodulation by β-Casomorphin-7 in Exacerbation of Ulcerative Colitis.
HMGB1/TREM2 positive feedback loop drives the development of radioresistance and immune escape of glioblastoma by regulating TLR4/Akt signaling.
FOXP3-regulated lncRNA NONHSAT136151 promotes colorectal cancer progression by disrupting QKI interaction with target mRNAs.
FOXP3 inhibits proliferation and migration by competitively inhibiting YAP1 in nasopharyngeal carcinoma.
Sea conch (Rapana venosa) peptide hydrolysate regulates NF-κB pathway and restores intestinal immune homeostasis in DSS-induced colitis mice.
NPSR1 promotes chronic colitis through regulating CD4(+) T cell effector function in inflammatory bowel disease.
β-Indole-3-acetic acid attenuated collagen-induced arthritis through reducing the ubiquitination of Foxp3 via the AhR-TAZ-Tip60 pathway.
A positive FOXP3/lncRNA SNHG1 feedback axis ameliorates cardiomyocytes hypertrophy by negatively regulating Parkin-mediated mitophagy.
Glycyrrhetinic acid inhibits non-small cell lung cancer via promotion of Prdx6- and caspase-3-mediated mitochondrial apoptosis.
Diaphorobacter nitroreducens synergize with oxaliplatin to reduce tumor burden in mice with lung adenocarcinoma.
Epigenetically regulated lncRNAs dissect the intratumoural heterogeneity and facilitate immune evasion of glioblastomas.
IGF2BP3-mediated regulation of GLS and GLUD1 gene expression promotes treg-induced immune escape in human cervical cancer.
Ileocecal involvement in intestinal Behçet's disease and Crohn's disease: comparison of clinicopathological and immunophenotypic features.
PCSK9 inhibition ameliorates experimental autoimmune myocarditis by reducing Th17 cell differentiation through LDLR/STAT-3/ROR-γt pathway.
Dietary alpha-ketoglutarate enhances intestinal immunity by Th17/Treg immune response in piglets after lipopolysaccharide challenge.
Effects of lactate on metabolism and differentiation of CD4(+)T cells.
Identification of a novel immune checkpoint molecule V-set immunoglobulin domain-containing 4 that leads to impaired immunity infiltration in pancreatic ductal adenocarcinoma.
The super-enhancer-driven lncRNA LINC00880 acts as a scaffold between CDK1 and PRDX1 to sustain the malignance of lung adenocarcinoma.
Regulatory T cells showed characteristics of T helper-17(Th17) cells in mice periodontitis model.
GPC1 Is Associated with Poor Prognosis and Treg Infiltration in Colon Adenocarcinoma.
Bifidobacterium infantis Promotes Foxp3 Expression in Colon Cells via PD-L1-Mediated Inhibition of the PI3K-Akt-mTOR Signaling Pathway.
Identification and experimental validation of a tumor-infiltrating lymphocytes-related long noncoding RNA signature for prognosis of clear cell renal cell carcinoma.
Gut Microbiota Protected Against pseudomonas aeruginosa Pneumonia via Restoring Treg/Th17 Balance and Metabolism.
The MBNL1/circNTRK2/PAX5 pathway regulates aerobic glycolysis in glioblastoma cells by encoding a novel protein NTRK2-243aa.
Oral Intervention of Narirutin Ameliorates the Allergic Response of Ovalbumin Allergy.
LncRNA-targeting bio-scaffold mediates triple immune effects for postoperative colorectal cancer immunotherapy.
Folic acid intervention changes liver Foxp3 methylation and ameliorates the damage caused by Th17/Treg imbalance after long-term alcohol exposure.
Polymeric indoximod based prodrug nanoparticles with doxorubicin entrapment for inducing immunogenic cell death and improving the immunotherapy of breast cancer.
Multi-material basis and multi-mechanisms of the Dahuang Zhechong pill for regulating Treg/Th1 balance in hepatocellular carcinoma.
Bifidobacterium infantis regulates the programmed cell death 1 pathway and immune response in mice with inflammatory bowel disease.
Qing-Chang-Hua-Shi granule ameliorates DSS-induced colitis by activating NLRP6 signaling and regulating Th17/Treg balance.
IGF2BP2-induced circRUNX1 facilitates the growth and metastasis of esophageal squamous cell carcinoma through miR-449b-5p/FOXP3 axis.
Panax notoginseng saponins prevent colitis-associated colorectal cancer via inhibition IDO1 mediated immune regulation.
Huganbuzure Granule Attenuates Concanavalin-A-Induced Immune Liver Injury in Mice via Regulating the Balance of Th1/Th2/Th17/Treg Cells and Inhibiting Apoptosis.
FOXP3 Inhibits the Metastasis of Breast Cancer by Downregulating the Expression of MTA1.
Self-assembled FeS-based cascade bioreactor with enhanced tumor penetration and synergistic treatments to trigger robust cancer immunotherapy.
The immunosuppressive role of Edn3 overexpression in the melanoma microenvironment.
Clinical and Molecular Characterizations of Papillary Thyroid Cancer in Children and Young Adults: A Multicenter Retrospective Study.
Mifepristone regulates Tregs function mediated by dendritic cells through suppressing the expression of TGF-β.
Aiduqing formula inhibits breast cancer metastasis by suppressing TAM/CXCL1-induced Treg differentiation and infiltration.
A PD-1 peptide antagonist exhibits potent anti-tumor and immune regulatory activity.
Glycolytic and lipid oxidative metabolic programs are essential for freshly-isolated regulatory T cells in mice with sepsis.
Regulatory T cell is critical for interleukin-33-mediated neuroprotection against stroke.
MiRNA-516a promotes bladder cancer metastasis by inhibiting MMP9 protein degradation via the AKT/FOXO3A/SMURF1 axis.
The Chinese medicinal herb decoction QRZSLXF enhances anti-inflammatory effect in TNBS-induced colitis via balancing Th17/Tregs differentiation.
SFRP4 is a prognostic marker and correlated with Treg cell infiltration in pancreatic ductal adenocarcinoma.
Changes in Tumor-Infiltrating Lymphocytes and Vascular Normalization in Breast Cancer Patients After Neoadjuvant Chemotherapy and Their Correlations With DFS.
DKK2 Impairs Tumor Immunity Infiltration and Correlates with Poor Prognosis in Pancreatic Ductal Adenocarcinoma.
The Hypermethylation of Foxp3 Promoter Impairs the Function of Treg Cells in EAP.
Bifidobacterium infantis Induces Protective Colonic PD-L1 and Foxp3 Regulatory T Cells in an Acute Murine Experimental Model of Inflammatory Bowel Disease.
Glycyrrhizic acid ammonium salt alleviates Concanavalin A-induced immunological liver injury in mice through the regulation of the balance of immune cells and the inhibition of hepatocyte apoptosis.
NF-κB-driven miR-34a impairs Treg/Th17 balance via targeting Foxp3.
Changes among TGF-β1(+) Breg cells and helper T cell subsets in a murine model of allergic rhinitis with prolonged OVA challenge.
Clinical significance of programmed death 1/programmed death ligand 1 pathway in gastric neuroendocrine carcinomas.
PPAR-γ Agonist Alleviates Liver and Spleen Pathology via Inducing Treg Cells during Schistosoma japonicum Infection.
Deletion of the C6orf120 gene with unknown function ameliorates autoimmune hepatitis induced by concanavalin A.
Kuijieling regulates the differentiation of Treg and Th17 cells to ameliorate experimental colitis in rats.
Erythropoietin Treatment Ameliorates Lupus Nephritis of MRL/lpr Mice.
Sonodynamic therapy-assisted immunotherapy: A novel modality for cancer treatment.
Epigenetic Regulation of CXCL12 Plays a Critical Role in Mediating Tumor Progression and the Immune Response In Osteosarcoma.
Faecalibacterium prausnitzii Produces Butyrate to Maintain Th17/Treg Balance and to Ameliorate Colorectal Colitis by Inhibiting Histone Deacetylase 1.
Regulatory effect of baicalin on the imbalance of Th17/Treg responses in mice with allergic asthma.
Upregulated Expression of microRNA-16 Correlates with Th17/Treg Cell Imbalance in Patients with Rheumatoid Arthritis.
Effect of IL-17 in the development of colon cancer in mice.
The Dynamics of Treg/Th17 and the Imbalance of Treg/Th17 in Clonorchis sinensis-Infected Mice.
rFliC prolongs allograft survival in association with the activation of recipient Tregs in a TLR5-dependent manner.
Up-regulation of microRNA-210 induces immune dysfunction via targeting FOXP3 in CD4(+) T cells of psoriasis vulgaris.
He Y, Qian Y, Zheng Z, Zhou Y, Li C, Wu Q, Ren M
Human mutation 2026;2026:8861747
Human mutation 2026;2026:8861747
Danggui Shaoyao San ameliorates neuroinflammation in a D-galactose-induced Alzheimer's disease rat model by suppressing the JAK2/STAT3 pathway and modulating Th17/Treg -related immune dysregulation.
Fu G, Tang S, Sun X, Tong J, Zhou M, Li P, Meng P, Cheng S, Song Z
Frontiers in cell and developmental biology 2026;14:1763180
Frontiers in cell and developmental biology 2026;14:1763180
LIFUS-driven engineered bacteria reprogram immunosuppressive niches via mechano-NOTCH signaling.
Lin L, Li X, Guo W, Xie J, Li X, Guan X, Zhao C, Yin H, Xu H
Cell reports. Medicine 2026 Mar 17;7(3):102658
Cell reports. Medicine 2026 Mar 17;7(3):102658
TONSL promotes hepatocellular carcinoma progression and radioresistance by orchestrating DNA damage repair and cell cycle dynamics.
Luo MR, Liao JL, Fang SJ, Zhang DY, Lei L
Discover oncology 2026 Mar 12;17(1)
Discover oncology 2026 Mar 12;17(1)
Diallyl Trisulfide Suppresses Tumor-Associated Macrophage M2-Like Polarization and Recruitment and Improves the Tumor Microenvironment Through Blocking CCL5/STAT3 Signaling Pathway Against Lung Cancer.
Xie C, Yin J, Zhu J
Phytotherapy research : PTR 2026 Jan;40(1):318-333
Phytotherapy research : PTR 2026 Jan;40(1):318-333
Curcumin inhibits HIV-1 by modulating FOXP3 and suppressing CCR5 via PI3K/AKT and JAK/STAT pathways.
Shi M, Li Q, Zheng W, Li Q, Jiang M, Zhang J, Wang Z, Qiao L, Feng L
Journal of virological methods 2026 Jan;339:115261
Journal of virological methods 2026 Jan;339:115261
SIGLEC15 modulates the immunosuppressive microenvironment and suppresses malignant phenotypes in triple-negative breast cancer.
Tan Z, Xin H, Chen J, Lei M, Tu G, Tang L
Genes & diseases 2026 Jan;13(1):101799
Genes & diseases 2026 Jan;13(1):101799
STT3A-mediated FCN3 N-glycosylation promotes Treg cell activation to drive hepatocellular carcinoma progression via Wnt/β-catenin.
Zhang H, Zhang P, Gong T, Zhang C, Wang Z, Zhao Y
Cellular oncology (Dordrecht, Netherlands) 2026 Jan 6;49(1):16
Cellular oncology (Dordrecht, Netherlands) 2026 Jan 6;49(1):16
Prediction of tumor-infiltrating lymphocytes through habitat radiomics and exploration of response mechanisms in neoadjuvant immunochemotherapy-treated lung cancer.
Geng Z, Hu Y, Zhou S, Wu G, Gong Z, Feng R, Huang Z, Mei P, Li K, Ye G, Liao Y
Cancer immunology, immunotherapy : CII 2026 Jan 27;75(2):42
Cancer immunology, immunotherapy : CII 2026 Jan 27;75(2):42
TRIP13 promotes the expansion and immunosuppression of CD4(+)Foxp3(+) regulatory T cells by sustaining HAT1 stability.
He T, Zhao L, Feng CT, Zhao LY, Jing S, Yang H, Wang K, Ye S, Zhao Y, Yu Y, Fu Z, Chou CK, Chen X, Gao YJ
Cell death & disease 2026 Jan 14;17(1):32
Cell death & disease 2026 Jan 14;17(1):32
BMP9 potentiates immunotherapy in triple-negative breast cancer by suppressing Tregs infiltration via the PRKDC-CCL2 axis.
You Y, Wei L, Dai M, Zhao G, Fan K, Dang T, Sun H, Zhang L, Li Q, Sun M, Li X, He X, Yang S, Zeng T, Tang J, Zhang Y
Cancer letters 2026 Feb 28;639:218175
Cancer letters 2026 Feb 28;639:218175
LDRT combined with anti-PD-1 promotes tumor regression in head and neck squamous cell carcinoma through tumor metaprogram evolution and immune cell reprogramming.
Li G, Yang X, Huang L, Zheng Y, Xu L, Zhang Z, Li J, Li T, Zhang Y, Yang Y, Li Y, Liu Z
Journal of experimental & clinical cancer research : CR 2026 Feb 11;45(1)
Journal of experimental & clinical cancer research : CR 2026 Feb 11;45(1)
TSP-1-CD47-integrin α4β1 axis drives T cell infiltration and synovial inflammation in rheumatoid arthritis.
Hu J, Wang X, Ge C, Qi W, Li Z, Wang Y, Lai W, Ji W, Xu H
Frontiers in immunology 2025;16:1524304
Frontiers in immunology 2025;16:1524304
The expression of autophagy-related gene CXCL12 in endometriosis associated ovarian cancer and pan-cancer analysis.
Yuan M, Chen S, Liao Z, Wang K
Frontiers in endocrinology 2025;16:1450892
Frontiers in endocrinology 2025;16:1450892
Fecal Microbiota Transplantation Modulates Th17/Treg Balance via JAK/STAT Pathway in ARDS Rats.
Zhang D, Dong B, Chen J, Zhang Z, Zeng W, Liao L, Xiong X, Qin X, Fan X
Advanced biology 2025 Sep;9(9):e00028
Advanced biology 2025 Sep;9(9):e00028
The Paeonol of Total Glucosides of White Peony Regulates the Differentiation of CD4+Treg Cells through the EP300/Foxp3 Axis to Relieve Pulmonary Fibrosis in Mice.
Yan M, Wang Q, Yang H, Liu D, Liang W, Chen H
Cell biochemistry and biophysics 2025 Sep;83(3):3959-3970
Cell biochemistry and biophysics 2025 Sep;83(3):3959-3970
PCV2 infection induces the differentiation of Treg cells via the TGF-β/Smad3 pathway.
Jiang R, Huang Q, Shen R, Zhang Y, Zhou L, Ge X, Han J, Guo X, Yang H
mBio 2025 Sep 10;16(9):e0136625
mBio 2025 Sep 10;16(9):e0136625
Lactiplantibacillus plantarum BD7807 ameliorates high-fat diet-induced lipid metabolic disorders and intestinal dysfunction via SCFAs-GPR43 pathway.
Li T, Wu J, Xia S, Yang H, Mu H, Zhu Y, Wu R, Liu Z
Food research international (Ottawa, Ont.) 2025 Nov;220:117108
Food research international (Ottawa, Ont.) 2025 Nov;220:117108
Study on the regulation of Treg cell infiltration by EZH2 through CXCR4/CXCL12 in diffuse large B-cell lymphoma.
Wang H, Liang D, Qian Y, Jiang Y, Yang R, Yin H
Clinical and experimental medicine 2025 Nov 25;26(1):30
Clinical and experimental medicine 2025 Nov 25;26(1):30
MeCP2 attenuates inflammation and regulates T cell phenotype via SFRP4 suppression in preeclampsia.
Peng M, Nie Y, Luo Y, Nkoua GDM, Zhang S, Liu H, Zhang W, Xiao S, Zhou Y, Lai W, Deng Y, Yu L, Liu J, Zhou X, Ding Y
Molecular and cellular endocrinology 2025 Nov 1;609:112637
Molecular and cellular endocrinology 2025 Nov 1;609:112637
MiR-519d-3p from Placenta-Derived Exosomes Induce Immune Intolerance Regulating Immune Cells, Contributing to the Pathogenesis of Preeclampsia.
Cao SQ, Jiang TX, Guo YY, Lin R, Lin L
Immunological investigations 2025 May;54(4):522-543
Immunological investigations 2025 May;54(4):522-543
Foxp3 inhibits PCV2 replication by reducing the ATPase activity of Rep.
Jiang R, Huang Q, Shen R, Zhang Y, Zhou L, Ge X, Han J, Guo X, Yang H
Veterinary microbiology 2025 May;304:110441
Veterinary microbiology 2025 May;304:110441
Phlorizin attenuates lupus nephritis via upregulating PI3K/Akt pathway-mediated Treg differentiation.
Jiang Z, Ruan X, Zhou X, Li S, Wang C, Huang L, He Z, Zhang Y, Wen C
International immunopharmacology 2025 May 8;154:114607
International immunopharmacology 2025 May 8;154:114607
L-Kynurenine regulates immune response in ICIs-associated myocarditis via JAK/STAT pathway.
He X, Zhang J, Zhang Y, Li H, Chen Y, Zhang H, Pan J, Zhou Y, Zhang S, Cheng L
International immunopharmacology 2025 May 27;156:114676
International immunopharmacology 2025 May 27;156:114676
Cryo-trojan mesenchymal stem cells as non-living tumor-homing supercarriers for enhanced drug delivery and immune activation in prostate cancer.
Wang C, Rong X, Zhang F, Mu X, Jiang J
Materials today. Bio 2025 Jun;32:101650
Materials today. Bio 2025 Jun;32:101650
The effect of vitamin C on the JAK/STAT3 pathway in ischemic stroke: based on the molecular interaction between FOXP3 protein and stat3 protein.
Lyu G, Wei W, Fan X, Zhong D, Li G
International journal of biological macromolecules 2025 Jun;311(Pt 4):144069
International journal of biological macromolecules 2025 Jun;311(Pt 4):144069
Andrographolide and its sulfated metabolite alleviated DSS-induced inflammatory bowel disease through regulating inflammation and immune via MAPK/NLRP3 pathways and the balance of Th17/Treg cells.
Zhang HL, Chang J, Sun CP, Huo ZP, Feng YL, Li PY, Jia YX, Hui SW, Zhu QM, Cai JY, He Y, Qiu F, Zhang J
Molecular immunology 2025 Jul;183:313-320
Molecular immunology 2025 Jul;183:313-320
Protective effects of polysaccharide of Atractylodes macrocephala Koidz and Jiawei Si-jun-zi Decoction on gut health and immune function in cyclophosphamide-treated chicks.
Lu B, Pan S, He J, Li B, Cao N, Fu X, Liu W, Huang Y, Tian Y, Xu D, Li W
Poultry science 2025 Jul;104(7):105160
Poultry science 2025 Jul;104(7):105160
Effect of RAS mutations and related immune characteristics on the prognosis of patients with MSI-H/dMMR colorectal cancer.
Jiang Y, Liu Y, Huang H, Zhao T, Zhao Z, Gao Y
Cancer immunology, immunotherapy : CII 2025 Feb 1;74(3):78
Cancer immunology, immunotherapy : CII 2025 Feb 1;74(3):78
Porcine decellularized splenic matrix hydrogel-based vesicle sustained-release System: A dual-regulatory biomaterial for accelerated wound healing via angiogenesis and immune remodeling.
Peng P, Fan S, Liu P, Huang X, Xuan Z, Liu A, Wu M, Sui B, Ye B, Zhang S, Guo H
Materials today. Bio 2025 Dec;35:102601
Materials today. Bio 2025 Dec;35:102601
FOXP3-activated KCNMB2-AS1 promotes clear cell renal cell carcinoma through the miR-744-3p/CD1D axis.
Huang G, Gui D, Guo Y, Luo S, Xu Z
Cell division 2025 Dec 19;21(1):4
Cell division 2025 Dec 19;21(1):4
Akkermansia Muciniphila Alleviates Severe Acute Pancreatitis via Amuc1409-Ube2k-Foxp3 Axis in Regulatory T Cells.
Xie J, Du L, Lu Y, Guo X, Zhou X, Tong Y, Shen B, Yu X, Guo F, Yu H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(30):e04214
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(30):e04214
Thalidomide mitigates Crohn's disease colitis by modulating gut microbiota, metabolites, and regulatory T cell immunity.
Tang CT, Wu Y, Tao Q, Zeng CY, Chen YX
Journal of pharmaceutical analysis 2025 Apr;15(4):101121
Journal of pharmaceutical analysis 2025 Apr;15(4):101121
Remodeling of Effector and Regulatory T Cells by Capture and Utilization of miRNAs Using Nanocomposite Hydrogel for Tumor-Specific Photothermal Immunotherapy.
Chen L, Zhu M, Zhang H, Tang W, Liu J, Tang X, Chang X, Zhu Z, Liu T, Weng L, Zhang Y, Chen X
ACS nano 2025 Apr 22;19(15):14873-14892
ACS nano 2025 Apr 22;19(15):14873-14892
Integrating bulk, single-cell, and spatial transcriptomics to identify and functionally validate novel targets to enhance immunotherapy in NSCLC.
Cao K, Wei S, Ma T, Yang X, Wang Y, He X, Lu M, Bai Y, Qi C, Zhang L, Li L, Meng H, Ma J, Zhu J
NPJ precision oncology 2025 Apr 16;9(1):112
NPJ precision oncology 2025 Apr 16;9(1):112
Curcumin chitosan microspheres regulate Th17/Treg balance via IGF2BP1- mediated m6A modification of LRP5 in ulcerative colitis.
Chen L, Xiang Y, Zhong S, Wu Y, Liu J, Wu Y, Wang Z, Huang G
Iranian journal of basic medical sciences 2024;27(10):1276-1283
Iranian journal of basic medical sciences 2024;27(10):1276-1283
Signals from intestinal microbiota mediate the crosstalk between the lung-gut axis in an influenza infection mouse model.
Zhang Y, Wan Y, Xin X, Qiao Y, Qiao W, Ping J, Su J
Frontiers in immunology 2024;15:1435180
Frontiers in immunology 2024;15:1435180
Beneficial effects of Dendrobium officinale National Herbal Drink on metabolic immune crosstalk via regulate SCFAs-Th17/Treg.
Dong YJ, Zhang YP, Jiang XF, Xie ZY, Li B, Jiang NH, Chen SH, Lv GY
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155816
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155816
Turning to immunosuppressive tumors: Deciphering the immunosenescence-related microenvironment and prognostic characteristics in pancreatic cancer, in which GLUT1 contributes to gemcitabine resistance.
Lu SY, Xu QC, Fang DL, Shi YH, Zhu YQ, Liu ZD, Ma MJ, Ye JY, Yin XY
Heliyon 2024 Sep 15;10(17):e36684
Heliyon 2024 Sep 15;10(17):e36684
Bergapten enhances mitophagy to regulate intestinal barrier and Th17/Treg balance in mice with Crohn's disease-like colitis via PPARγ/NF-κB signaling pathway.
Xu L, Zhao B, Cheng H, Li G, Sun Y
Naunyn-Schmiedeberg's archives of pharmacology 2024 Oct;397(10):7589-7597
Naunyn-Schmiedeberg's archives of pharmacology 2024 Oct;397(10):7589-7597
Investigating the mechanism of METTL16-dependent m6A modification regulating the SAMD11 protein signaling pathway to inhibit thyroid cancer phenotypes.
Liu Y, Wu G, Tao X, Dong J, Shi T, Shi C
International journal of biological macromolecules 2024 Nov;280(Pt 4):136176
International journal of biological macromolecules 2024 Nov;280(Pt 4):136176
RSPO3 regulates the radioresistance of Non-Small cell lung cancer cells via NLRP3 Inflammasome-Mediated pyroptosis.
Li H, Zhang J, Yu B, Yang T, Liu B, Li F, Jin X, Li Q
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2024 Nov;200:110528
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2024 Nov;200:110528
Targeting delivery of mifepristone to endometrial dysfunctional macrophages for endometriosis therapy.
Zhang M, Ye Y, Chen Z, Wu X, Chen Y, Zhao P, Zhao M, Zheng C
Acta biomaterialia 2024 Nov;189:505-518
Acta biomaterialia 2024 Nov;189:505-518
Aucklandiae radix targeted PKM2 to alleviate ulcerative colitis: Insights from the photocrosslinking target fishing technique.
Feng YL, Xu XR, Zhu QM, Chang J, Zhang HL, Wang N, Sun JB, Liu J, Zhang J, Sun CP
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155973
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155973
Rhomboid-like 2 correlated with TME infiltration inhibits cuproptosis-related genes and drives malignant phenotype in clear cell renal cell carcinoma.
Che Z, Jin W, Wu Y, Li H, Liang P
Scientific reports 2024 Nov 7;14(1):27053
Scientific reports 2024 Nov 7;14(1):27053
Tanshinone IIA potentiates the therapeutic efficacy of glucocorticoids in lipopolysaccharide-treated HEI-OC1 cells through modulation of the FOXP3/Nrf2 signaling pathway.
Li J, Zhu X, Ye S, Dong Q, Hou J, Liu J, She W
Acta biochimica et biophysica Sinica 2024 Nov 1;57(5):727-737
Acta biochimica et biophysica Sinica 2024 Nov 1;57(5):727-737
Expression landscape of cancer-FOXP3 and its prognostic value in pancreatic adenocarcinoma.
Gong R, Wang J, Xing Y, Wang J, Chen X, Lei K, Yu Q, Zhao C, Li S, Zhang Y, Wang H, Ren H
Cancer letters 2024 May 28;590:216838
Cancer letters 2024 May 28;590:216838
Fatostatin promotes anti-tumor immunity by reducing SREBP2 mediated cholesterol metabolism in tumor-infiltrating T lymphocytes.
Zhu L, Shi Y, Feng Z, Yuan D, Guo S, Wang Y, Shen H, Li Y, Yan F, Wang Y
European journal of pharmacology 2024 May 15;971:176519
European journal of pharmacology 2024 May 15;971:176519
Efficacy and Mechanism of the Action of Live and Heat-Killed Bacillus coagulans BC198 as Potential Probiotic in Ameliorating Dextran Sulfate Sodium-Induced Colitis in Mice.
Koh YC, Chang YC, Lin WS, Leung SY, Chen WJ, Wu SH, Wei YS, Gung CL, Chou YC, Pan MH
ACS omega 2024 Mar 5;9(9):10253-10266
ACS omega 2024 Mar 5;9(9):10253-10266
ROS-responsive drug-releasing injectable microgels for ameliorating myocardial infarction.
Wang S, Yao Y, Song L, Zhai Z, Li S, Wang Z, Shen L, Zhu Y, Liu W, Gao C
Biomaterials 2024 Jun;307:122534
Biomaterials 2024 Jun;307:122534
Significance of CD10 for Mucosal Immunomodulation by β-Casomorphin-7 in Exacerbation of Ulcerative Colitis.
Miyagawa Y, Fujiwara-Tani R, Ikemoto A, Sasaki R, Ogata R, Nishiguchi Y, Goto K, Kawahara I, Sasaki T, Kuniyasu H
Current issues in molecular biology 2024 Jun 26;46(7):6472-6488
Current issues in molecular biology 2024 Jun 26;46(7):6472-6488
HMGB1/TREM2 positive feedback loop drives the development of radioresistance and immune escape of glioblastoma by regulating TLR4/Akt signaling.
Qiu H, Shao Z, Wen X, Qu D, Liu Z, Chen Z, Zhang X, Ding X, Zhang L
Journal of translational medicine 2024 Jul 29;22(1):688
Journal of translational medicine 2024 Jul 29;22(1):688
FOXP3-regulated lncRNA NONHSAT136151 promotes colorectal cancer progression by disrupting QKI interaction with target mRNAs.
Huang H, Liang X, Wu W, Yuan T, Chen Z, Wang L, Wu Z, Zhang T, Yang K, Wen K
Journal of cellular and molecular medicine 2024 Jan;28(2):e18068
Journal of cellular and molecular medicine 2024 Jan;28(2):e18068
FOXP3 inhibits proliferation and migration by competitively inhibiting YAP1 in nasopharyngeal carcinoma.
Zang Y, Lu Y, Yu J, Dong Q, Shi Y, Ying G, Liang Z
Oral oncology 2024 Dec;159:107066
Oral oncology 2024 Dec;159:107066
Sea conch (Rapana venosa) peptide hydrolysate regulates NF-κB pathway and restores intestinal immune homeostasis in DSS-induced colitis mice.
Ullah H, Alioui Y, Ali M, Ali S, Farooqui NA, Siddiqui NZ, Alsholi DM, Ilyas M, Rahman MU, Xin Y, Wang L
Food science & nutrition 2024 Dec;12(12):10070-10086
Food science & nutrition 2024 Dec;12(12):10070-10086
NPSR1 promotes chronic colitis through regulating CD4(+) T cell effector function in inflammatory bowel disease.
Peng Y, Chen L, Chen X, Lin J, Wei J, Cheng J, Zhou F, Ge L, Zhou R, Ding F, Wang X
International immunopharmacology 2024 Dec 5;142(Pt B):113252
International immunopharmacology 2024 Dec 5;142(Pt B):113252
β-Indole-3-acetic acid attenuated collagen-induced arthritis through reducing the ubiquitination of Foxp3 via the AhR-TAZ-Tip60 pathway.
Su X, Wang X, Zhang X, Sun Y, Jia Y
Immunologic research 2024 Aug;72(4):741-753
Immunologic research 2024 Aug;72(4):741-753
A positive FOXP3/lncRNA SNHG1 feedback axis ameliorates cardiomyocytes hypertrophy by negatively regulating Parkin-mediated mitophagy.
Zhang J, Luo X, Yang X, Wang B, Zheng L, Yan S
International immunopharmacology 2024 Aug 20;137:112526
International immunopharmacology 2024 Aug 20;137:112526
Glycyrrhetinic acid inhibits non-small cell lung cancer via promotion of Prdx6- and caspase-3-mediated mitochondrial apoptosis.
Guo Q, Zhao M, Wang Q, Lu T, Luo P, Chen L, Xia F, Pang H, Shen S, Cheng G, Dai C, Meng Y, Zhong T, Qiu C, Wang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116304
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116304
Diaphorobacter nitroreducens synergize with oxaliplatin to reduce tumor burden in mice with lung adenocarcinoma.
Ni Y, Li R, Shen X, Yi D, Ren Y, Wang F, Geng Y, You Q
mSystems 2024 Apr 16;9(4):e0132323
mSystems 2024 Apr 16;9(4):e0132323
Epigenetically regulated lncRNAs dissect the intratumoural heterogeneity and facilitate immune evasion of glioblastomas.
Xu D, Cao M, Wang B, Bi X, Zhang H, Wu D, Zhang C, Xu J, Xu Z, Zheng D, Chen L, Li P, Wang H, Liu Y, Jiang H, Li K
Theranostics 2023;13(5):1490-1505
Theranostics 2023;13(5):1490-1505
IGF2BP3-mediated regulation of GLS and GLUD1 gene expression promotes treg-induced immune escape in human cervical cancer.
Zhou T, Xiao Z, Lu J, Zhang L, Bo L, Wang J
American journal of cancer research 2023;13(11):5289-5305
American journal of cancer research 2023;13(11):5289-5305
Ileocecal involvement in intestinal Behçet's disease and Crohn's disease: comparison of clinicopathological and immunophenotypic features.
Wu YC, Fu YJ, Xia HJ, Zhu J, Huang Y, Jiang ZN
Journal of digestive diseases 2023 Nov;24(11):594-602
Journal of digestive diseases 2023 Nov;24(11):594-602
PCSK9 inhibition ameliorates experimental autoimmune myocarditis by reducing Th17 cell differentiation through LDLR/STAT-3/ROR-γt pathway.
Yu M, Tang W, Liang W, Xie B, Gao R, Ding P, Gu X, Wang M, Wen S, Sun P
International immunopharmacology 2023 Nov;124(Pt B):110962
International immunopharmacology 2023 Nov;124(Pt B):110962
Dietary alpha-ketoglutarate enhances intestinal immunity by Th17/Treg immune response in piglets after lipopolysaccharide challenge.
Liu GM, Lu JJ, Sun WX, Jia G, Zhao H, Chen XL, Tian G, Cai JY, Zhang RN, Wang J
Journal of animal science 2023 Jan 3;101
Journal of animal science 2023 Jan 3;101
Effects of lactate on metabolism and differentiation of CD4(+)T cells.
Zhang YT, Xing ML, Fang HH, Li WD, Wu L, Chen ZP
Molecular immunology 2023 Feb;154:96-107
Molecular immunology 2023 Feb;154:96-107
Identification of a novel immune checkpoint molecule V-set immunoglobulin domain-containing 4 that leads to impaired immunity infiltration in pancreatic ductal adenocarcinoma.
Jiang Y, Han L, Yang J, Yang M, Zhang J, Xue M, Zhu Y, Xiong C, Shi M, Zhao S, Shen B, Xu Z, Jiang L, Chen H
Cancer immunology, immunotherapy : CII 2023 Aug;72(8):2701-2716
Cancer immunology, immunotherapy : CII 2023 Aug;72(8):2701-2716
The super-enhancer-driven lncRNA LINC00880 acts as a scaffold between CDK1 and PRDX1 to sustain the malignance of lung adenocarcinoma.
Feng Y, Zhang T, Zhang Z, Liang Y, Wang H, Chen Y, Yu X, Song X, Mao Q, Xia W, Chen B, Xu L, Dong G, Jiang F
Cell death & disease 2023 Aug 24;14(8):551
Cell death & disease 2023 Aug 24;14(8):551
Regulatory T cells showed characteristics of T helper-17(Th17) cells in mice periodontitis model.
Kou Y, Jiang Y, Liu S, Yang P, Lu Y, Liu H, Li M
Oral diseases 2023 Apr;29(3):1149-1162
Oral diseases 2023 Apr;29(3):1149-1162
GPC1 Is Associated with Poor Prognosis and Treg Infiltration in Colon Adenocarcinoma.
Liu Y, Ren H, Yang MQ, Li JY
Computational and mathematical methods in medicine 2022;2022:8209700
Computational and mathematical methods in medicine 2022;2022:8209700
Bifidobacterium infantis Promotes Foxp3 Expression in Colon Cells via PD-L1-Mediated Inhibition of the PI3K-Akt-mTOR Signaling Pathway.
Zhou L, Xie Y, Li Y
Frontiers in immunology 2022;13:871705
Frontiers in immunology 2022;13:871705
Identification and experimental validation of a tumor-infiltrating lymphocytes-related long noncoding RNA signature for prognosis of clear cell renal cell carcinoma.
Deng Y, Guo K, Tang Z, Feng Y, Cai S, Ye J, Xi Y, Li J, Liu R, Cai C, Tan Z, Zhang Y, Han Z, Zeng G, Zhong W
Frontiers in immunology 2022;13:1046790
Frontiers in immunology 2022;13:1046790
Gut Microbiota Protected Against pseudomonas aeruginosa Pneumonia via Restoring Treg/Th17 Balance and Metabolism.
Wen L, Shi L, Kong XL, Li KY, Li H, Jiang DX, Zhang F, Zhou ZG
Frontiers in cellular and infection microbiology 2022;12:856633
Frontiers in cellular and infection microbiology 2022;12:856633
The MBNL1/circNTRK2/PAX5 pathway regulates aerobic glycolysis in glioblastoma cells by encoding a novel protein NTRK2-243aa.
Zhao Y, Song J, Dong W, Liu X, Yang C, Wang D, Xue Y, Ruan X, Liu L, Wang P, Zhang M, Liu Y
Cell death & disease 2022 Sep 5;13(9):767
Cell death & disease 2022 Sep 5;13(9):767
Oral Intervention of Narirutin Ameliorates the Allergic Response of Ovalbumin Allergy.
Shi X, Zhao L, Niu L, Yan Y, Chen Q, Jin Y, Li X
Journal of agricultural and food chemistry 2022 Oct 19;70(41):13313-13326
Journal of agricultural and food chemistry 2022 Oct 19;70(41):13313-13326
LncRNA-targeting bio-scaffold mediates triple immune effects for postoperative colorectal cancer immunotherapy.
Liu F, Dai Z, Cheng Q, Xu L, Huang L, Liu Z, Li X, Wang N, Wang G, Wang L, Wang Z
Biomaterials 2022 May;284:121485
Biomaterials 2022 May;284:121485
Folic acid intervention changes liver Foxp3 methylation and ameliorates the damage caused by Th17/Treg imbalance after long-term alcohol exposure.
Zhao H, Guo P, Zuo Y, Wang Y, Zhao H, Lan T, Xue M, Zhang H, Liang H
Food & function 2022 May 10;13(9):5262-5274
Food & function 2022 May 10;13(9):5262-5274
Polymeric indoximod based prodrug nanoparticles with doxorubicin entrapment for inducing immunogenic cell death and improving the immunotherapy of breast cancer.
Zang X, Song J, Yi X, Piyu J
Journal of materials chemistry. B 2022 Mar 23;10(12):2019-2027
Journal of materials chemistry. B 2022 Mar 23;10(12):2019-2027
Multi-material basis and multi-mechanisms of the Dahuang Zhechong pill for regulating Treg/Th1 balance in hepatocellular carcinoma.
Wu L, Yang FR, Xing ML, Lu SF, Chen HL, Yang QW, Zhang YT, Lu Y, Huang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154055
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154055
Bifidobacterium infantis regulates the programmed cell death 1 pathway and immune response in mice with inflammatory bowel disease.
Zhou LY, Xie Y, Li Y
World journal of gastroenterology 2022 Jul 14;28(26):3164-3176
World journal of gastroenterology 2022 Jul 14;28(26):3164-3176
Qing-Chang-Hua-Shi granule ameliorates DSS-induced colitis by activating NLRP6 signaling and regulating Th17/Treg balance.
Cheng C, Hu J, Li Y, Ji Y, Lian Z, Au R, Xu F, Li W, Shen H, Zhu L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Dec;107:154452
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Dec;107:154452
IGF2BP2-induced circRUNX1 facilitates the growth and metastasis of esophageal squamous cell carcinoma through miR-449b-5p/FOXP3 axis.
Wang C, Zhou M, Zhu P, Ju C, Sheng J, Du D, Wan J, Yin H, Xing Y, Li H, He J, He F
Journal of experimental & clinical cancer research : CR 2022 Dec 15;41(1):347
Journal of experimental & clinical cancer research : CR 2022 Dec 15;41(1):347
Panax notoginseng saponins prevent colitis-associated colorectal cancer via inhibition IDO1 mediated immune regulation.
Li XM, Yuan DY, Liu YH, Zhu L, Qin HK, Yang YB, Li Y, Yan F, Wang YJ
Chinese journal of natural medicines 2022 Apr;20(4):258-269
Chinese journal of natural medicines 2022 Apr;20(4):258-269
Huganbuzure Granule Attenuates Concanavalin-A-Induced Immune Liver Injury in Mice via Regulating the Balance of Th1/Th2/Th17/Treg Cells and Inhibiting Apoptosis.
Wang M, Yin H, Xia Y, Tu Y, Zou X, Song W, Luo L, Wu H, Yang Y, Zan J, Liu Y, Dan H, Yin Q, You P
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5578021
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5578021
FOXP3 Inhibits the Metastasis of Breast Cancer by Downregulating the Expression of MTA1.
Liu C, Han J, Li X, Huang T, Gao Y, Wang B, Zhang K, Wang S, Zhang W, Li W, Hao Q, Li M, Zhang Y, Zhang C
Frontiers in oncology 2021;11:656190
Frontiers in oncology 2021;11:656190
Self-assembled FeS-based cascade bioreactor with enhanced tumor penetration and synergistic treatments to trigger robust cancer immunotherapy.
Ren H, Yong J, Yang Q, Yang Z, Liu Z, Xu Y, Wang H, Jiang X, Miao W, Li X
Acta pharmaceutica Sinica. B 2021 Oct;11(10):3244-3261
Acta pharmaceutica Sinica. B 2021 Oct;11(10):3244-3261
The immunosuppressive role of Edn3 overexpression in the melanoma microenvironment.
Freitas JT, Lopez J, Llorian C, Boroni M, Kos L
Pigment cell & melanoma research 2021 Nov;34(6):1084-1093
Pigment cell & melanoma research 2021 Nov;34(6):1084-1093
Clinical and Molecular Characterizations of Papillary Thyroid Cancer in Children and Young Adults: A Multicenter Retrospective Study.
Guo K, Qian K, Shi Y, Sun T, Chen L, Mei D, Dong K, Gu S, Liu J, Lv Z, Wang Z
Thyroid : official journal of the American Thyroid Association 2021 Nov;31(11):1693-1706
Thyroid : official journal of the American Thyroid Association 2021 Nov;31(11):1693-1706
Mifepristone regulates Tregs function mediated by dendritic cells through suppressing the expression of TGF-β.
Li Y, Cao L, Qian Z, Guo Q, Niu X, Huang L
Immunopharmacology and immunotoxicology 2021 Feb;43(1):85-93
Immunopharmacology and immunotoxicology 2021 Feb;43(1):85-93
Aiduqing formula inhibits breast cancer metastasis by suppressing TAM/CXCL1-induced Treg differentiation and infiltration.
Li J, Wang S, Wang N, Zheng Y, Yang B, Wang X, Zhang J, Pan B, Wang Z
Cell communication and signaling : CCS 2021 Aug 30;19(1):89
Cell communication and signaling : CCS 2021 Aug 30;19(1):89
A PD-1 peptide antagonist exhibits potent anti-tumor and immune regulatory activity.
Tao H, Cheng L, Liu L, Wang H, Jiang Z, Qiang X, Xing L, Xu Y, Cai X, Yao J, Wang M, Qiu Z
Cancer letters 2020 Nov 28;493:91-101
Cancer letters 2020 Nov 28;493:91-101
Glycolytic and lipid oxidative metabolic programs are essential for freshly-isolated regulatory T cells in mice with sepsis.
Zhu X, Ji W, Guo S, Zhu D, Yang Y, Liu X
RSC advances 2020 May 27;10(35):21000-21008
RSC advances 2020 May 27;10(35):21000-21008
Regulatory T cell is critical for interleukin-33-mediated neuroprotection against stroke.
Liu X, Hu R, Pei L, Si P, Wang C, Tian X, Wang X, Liu H, Wang B, Xia Z, Xu Y, Song B
Experimental neurology 2020 Jun;328:113233
Experimental neurology 2020 Jun;328:113233
MiRNA-516a promotes bladder cancer metastasis by inhibiting MMP9 protein degradation via the AKT/FOXO3A/SMURF1 axis.
Chang Y, Jin H, Li H, Ma J, Zheng Z, Sun B, Lyu Y, Lin M, Zhao H, Shen L, Zhang R, Wu S, Lin W, Lu Y, Xie Q, Zhang G, Huang X, Huang H
Clinical and translational medicine 2020 Dec;10(8):e263
Clinical and translational medicine 2020 Dec;10(8):e263
The Chinese medicinal herb decoction QRZSLXF enhances anti-inflammatory effect in TNBS-induced colitis via balancing Th17/Tregs differentiation.
Zhang M, Fan H, Tan S, Tang Q, Liu X, Zuo D, Liao Y, Nan Z, Tan C
Journal of ethnopharmacology 2020 Apr 6;251:112549
Journal of ethnopharmacology 2020 Apr 6;251:112549
SFRP4 is a prognostic marker and correlated with Treg cell infiltration in pancreatic ductal adenocarcinoma.
Yang MW, Tao LY, Yang JY, Jiang YS, Fu XL, Liu W, Huo YM, Li J, Zhang JF, Hua R, Qin XR, Sun YW, Liu DJ
American journal of cancer research 2019;9(2):363-377
American journal of cancer research 2019;9(2):363-377
Changes in Tumor-Infiltrating Lymphocytes and Vascular Normalization in Breast Cancer Patients After Neoadjuvant Chemotherapy and Their Correlations With DFS.
Wang Q, Xiang Q, Yu L, Hu T, Chen Y, Wang J, Nie X, Cheng J
Frontiers in oncology 2019;9:1545
Frontiers in oncology 2019;9:1545
DKK2 Impairs Tumor Immunity Infiltration and Correlates with Poor Prognosis in Pancreatic Ductal Adenocarcinoma.
Yang J, Jiang Y, He R, Liu W, Yang M, Tao L, Fu X, Shen Y, Li J, Liu D, Huo Y, Zhang J, Hua R, Zhang Z, Sun Y
Journal of immunology research 2019;2019:8656282
Journal of immunology research 2019;2019:8656282
The Hypermethylation of Foxp3 Promoter Impairs the Function of Treg Cells in EAP.
Chen J, Zhan C, Zhang L, Zhang L, Liu Y, Zhang Y, Du H, Liang C, Chen X
Inflammation 2019 Oct;42(5):1705-1718
Inflammation 2019 Oct;42(5):1705-1718
Bifidobacterium infantis Induces Protective Colonic PD-L1 and Foxp3 Regulatory T Cells in an Acute Murine Experimental Model of Inflammatory Bowel Disease.
Zhou L, Liu D, Xie Y, Yao X, Li Y
Gut and liver 2019 Mar 15;13(4):430-439
Gut and liver 2019 Mar 15;13(4):430-439
Glycyrrhizic acid ammonium salt alleviates Concanavalin A-induced immunological liver injury in mice through the regulation of the balance of immune cells and the inhibition of hepatocyte apoptosis.
Tian X, Liu Y, Liu X, Gao S, Sun X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109481
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109481
NF-κB-driven miR-34a impairs Treg/Th17 balance via targeting Foxp3.
Xie M, Wang J, Gong W, Xu H, Pan X, Chen Y, Ru S, Wang H, Chen X, Zhao Y, Li J, Yin Q, Xia S, Zhou X, Liu X, Shao Q
Journal of autoimmunity 2019 Aug;102:96-113
Journal of autoimmunity 2019 Aug;102:96-113
Changes among TGF-β1(+) Breg cells and helper T cell subsets in a murine model of allergic rhinitis with prolonged OVA challenge.
Wang M, Gu Z, Yang J, Zhao H, Cao Z
International immunopharmacology 2019 Apr;69:347-357
International immunopharmacology 2019 Apr;69:347-357
Clinical significance of programmed death 1/programmed death ligand 1 pathway in gastric neuroendocrine carcinomas.
Yang MW, Fu XL, Jiang YS, Chen XJ, Tao LY, Yang JY, Huo YM, Liu W, Zhang JF, Liu PF, Liu Q, Hua R, Zhang ZG, Sun YW, Liu DJ
World journal of gastroenterology 2019 Apr 14;25(14):1684-1696
World journal of gastroenterology 2019 Apr 14;25(14):1684-1696
PPAR-γ Agonist Alleviates Liver and Spleen Pathology via Inducing Treg Cells during Schistosoma japonicum Infection.
Zhu Y, Ni Y, Liu R, Hou M, Yang B, Song J, Sun H, Xu Z, Ji M
Journal of immunology research 2018;2018:6398078
Journal of immunology research 2018;2018:6398078
Deletion of the C6orf120 gene with unknown function ameliorates autoimmune hepatitis induced by concanavalin A.
Zhang MK, Ma HM, Zhang J, Song XC, Ye XH, Li YF, Zhang YF, He LL, Wei HS, Li X
Cellular immunology 2018 Sep;331:9-15
Cellular immunology 2018 Sep;331:9-15
Kuijieling regulates the differentiation of Treg and Th17 cells to ameliorate experimental colitis in rats.
Long Y, Li S, Qin J, Xie L, Gan L, Jie F, Wu Y, Li Y, Du Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Sep;105:781-788
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Sep;105:781-788
Erythropoietin Treatment Ameliorates Lupus Nephritis of MRL/lpr Mice.
Zhang Z, Liu D, Zhang X, Wang X
Inflammation 2018 Oct;41(5):1888-1899
Inflammation 2018 Oct;41(5):1888-1899
Sonodynamic therapy-assisted immunotherapy: A novel modality for cancer treatment.
Zhang Q, Bao C, Cai X, Jin L, Sun L, Lang Y, Li L
Cancer science 2018 May;109(5):1330-1345
Cancer science 2018 May;109(5):1330-1345
Epigenetic Regulation of CXCL12 Plays a Critical Role in Mediating Tumor Progression and the Immune Response In Osteosarcoma.
Li B, Wang Z, Wu H, Xue M, Lin P, Wang S, Lin N, Huang X, Pan W, Liu M, Yan X, Qu H, Sun L, Li H, Wu Y, Teng W, Wang Z, Zhou X, Chen H, Poznansky MC, Ye Z
Cancer research 2018 Jul 15;78(14):3938-3953
Cancer research 2018 Jul 15;78(14):3938-3953
Faecalibacterium prausnitzii Produces Butyrate to Maintain Th17/Treg Balance and to Ameliorate Colorectal Colitis by Inhibiting Histone Deacetylase 1.
Zhou L, Zhang M, Wang Y, Dorfman RG, Liu H, Yu T, Chen X, Tang D, Xu L, Yin Y, Pan Y, Zhou Q, Zhou Y, Yu C
Inflammatory bowel diseases 2018 Aug 16;24(9):1926-1940
Inflammatory bowel diseases 2018 Aug 16;24(9):1926-1940
Regulatory effect of baicalin on the imbalance of Th17/Treg responses in mice with allergic asthma.
Xu L, Li J, Zhang Y, Zhao P, Zhang X
Journal of ethnopharmacology 2017 Aug 17;208:199-206
Journal of ethnopharmacology 2017 Aug 17;208:199-206
Upregulated Expression of microRNA-16 Correlates with Th17/Treg Cell Imbalance in Patients with Rheumatoid Arthritis.
Wu YH, Liu W, Xue B, Zhang L, Liu XY, Liu B, Wang Y, Cai Y, Duan R
DNA and cell biology 2016 Dec;35(12):853-860
DNA and cell biology 2016 Dec;35(12):853-860
Effect of IL-17 in the development of colon cancer in mice.
Yang L, Liu H, Zhang L, Hu J, Chen H, Wang L, Yin X, Li Q, Qi Y
Oncology letters 2016 Dec;12(6):4929-4936
Oncology letters 2016 Dec;12(6):4929-4936
The Dynamics of Treg/Th17 and the Imbalance of Treg/Th17 in Clonorchis sinensis-Infected Mice.
Yan C, Zhang BB, Hua H, Li B, Zhang B, Yu Q, Li XY, Liu Y, Pan W, Liu XY, Tang RX, Zheng KY
PloS one 2015;10(11):e0143217
PloS one 2015;10(11):e0143217
rFliC prolongs allograft survival in association with the activation of recipient Tregs in a TLR5-dependent manner.
Hao J, Zhang C, Liang T, Song J, Hou G
Cellular & molecular immunology 2014 Mar;11(2):206-14
Cellular & molecular immunology 2014 Mar;11(2):206-14
Up-regulation of microRNA-210 induces immune dysfunction via targeting FOXP3 in CD4(+) T cells of psoriasis vulgaris.
Zhao M, Wang LT, Liang GP, Zhang P, Deng XJ, Tang Q, Zhai HY, Chang CC, Su YW, Lu QJ
Clinical immunology (Orlando, Fla.) 2014 Jan;150(1):22-30
Clinical immunology (Orlando, Fla.) 2014 Jan;150(1):22-30
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 22228-1-AP(FOXP3 antibody) at dilution of 1:2000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The FOXP3 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human FOXP3. This antibody recognizes human,mouse,rat antigen. The FOXP3 antibody has been validated for the following applications: ELISA, WB, IP analysis.
