HPA037364

antibody from Atlas Antibodies

Targeting: YTHDC2 DKFZp564A186, FLJ10053, FLJ2194

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA037364

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA037364, RRID:AB_10672788

Product name

Anti-YTHDC2

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human YTHDC2, Gene description: YTH domain containing 2, Alternative Gene Names: DKFZp564A186, FLJ10053, FLJ2194, Validated applications: IHC, Uniprot ID: Q9H6S0, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.5 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Pathogenic variants in the human m6A reader YTHDC2 are associated with primary ovarian insufficiency

McGlacken-Byrne S, Del Valle I, Quesne Stabej P, Bellutti L, Garcia-Alonso L, Ocaka L, Ishida M, Suntharalingham J, Gagunashvili A, Ogunbiyi O, Mistry T, Buonocore F, GOSgene , Crespo B, Moreno N, Niola P, Brooks T, Brain C, Dattani M, Kelberman D, Vento-Tormo R, Lagos C, Livera G, Conway G, Achermann J
JCI Insight 2022;7(5)

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m6A Reader YTHDC2 Promotes Radiotherapy Resistance of Nasopharyngeal Carcinoma via Activating IGF1R/AKT/S6 Signaling Axis

He J, Li Z, Rong Z, Gao J, Mu Y, Guan Y, Ren X, Zi Y, Liu L, Fan Q, Zhou M, Duan Y, Zhou Q, Deng Y, Sun L
Frontiers in Oncology 2020;10

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The m6A reader protein YTHDC2 interacts with the small ribosomal subunit and the 5′–3′ exoribonuclease XRN1

Kretschmer J, Rao H, Hackert P, Sloan K, Höbartner C, Bohnsack M
RNA 2018;24(10):1339-1350