Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 11-12025-25 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-Otx2 Antibody
- Antibody type
- Polyclonal
- Description
- Otx2 encodes a transcription factor that plays a critical role in craniofacial development and anterior brain morphogenesis. Otx2 homologs in model organisms are expressed in a complex spatial, temporal, and gradient-specific manner that is required for correct antero-posterior patterning and craniofacial development. Otx2 mutations are associated with severe ocular phenotypes and central nervous system abnormalities such as seizures, short stature and developmental delay, CPHD (Combined Pituitary Hormone Deficiency), structural abnormalities of the pituitary gland and early onset retinal dystrophy.
- Reactivity
- Human
- Host
- Rabbit
- Antigen sequence
A partial length recombinant Otx2 p
rotein (amino acids 1-204) was used
as the immunogen for this antibody
.- Vial size
- 25 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
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Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Expression analysis of Otx2. Anti-Otx2 antibody (11-12025) was used at 2 µg/ml on Jurkat lysate.