Explore
Validate
Learn
Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- HPA036978 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA036978, RRID:AB_10964347
- Product name
- Anti-PGAM5
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human PGAM5, Gene description: phosphoglycerate mutase family member 5, Alternative Gene Names: BXLBv68, MGC5352, Validated applications: ICC, IHC, WB, Uniprot ID: Q96HS1, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Targeting oxeiptosis-mediated tumor suppression: a novel approach to treat colorectal cancers by sanguinarine
A novel role of KEAP1/PGAM5 complex: ROS sensor for inducing mitophagy.
PGAM5 is a key driver of mitochondrial dysfunction in experimental lung fibrosis
PISDis a mitochondrial disease gene causing skeletal dysplasia, cataracts, and white matter changes
Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway
Pallichankandy S, Thayyullathil F, Cheratta A, Subburayan K, Alakkal A, Sultana M, Drou N, Arshad M, Tariq S, Galadari S
Cell Death Discovery 2023;9(1)
Cell Death Discovery 2023;9(1)
A novel role of KEAP1/PGAM5 complex: ROS sensor for inducing mitophagy.
Zeb A, Choubey V, Gupta R, Kuum M, Safiulina D, Vaarmann A, Gogichaishvili N, Liiv M, Ilves I, Tämm K, Veksler V, Kaasik A
Redox biology 2021 Nov 11;48:102186
Redox biology 2021 Nov 11;48:102186
PGAM5 is a key driver of mitochondrial dysfunction in experimental lung fibrosis
Ganzleben I, He G, Günther C, Prigge E, Richter K, Rieker R, Mougiakakos D, Neurath M, Becker C
Cellular and Molecular Life Sciences 2019;76(23):4783-4794
Cellular and Molecular Life Sciences 2019;76(23):4783-4794
PISDis a mitochondrial disease gene causing skeletal dysplasia, cataracts, and white matter changes
Zhao T, Goedhart C, Sam P, Sabouny R, Lingrell S, Cornish A, Lamont R, Bernier F, Sinasac D, Parboosingh J, Vance J, Claypool S, Innes A, Shutt T
Life Science Alliance 2019;2(2):e201900353
Life Science Alliance 2019;2(2):e201900353
Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway
Holze C, Michaudel C, Mackowiak C, Haas D, Benda C, Hubel P, Pennemann F, Schnepf D, Wettmarshausen J, Braun M, Leung D, Amarasinghe G, Perocchi F, Staeheli P, Ryffel B, Pichlmair A
Nature Immunology 2017;19(2):130-140
Nature Immunology 2017;19(2):130-140
No comments: Submit comment
Enhanced validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Genetic validation
- Main image
- Experimental details
- Western blot analysis in RT-4 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-PGAM5 antibody. Remaining relative intensity is presented. Loading control: Anti-PPIB.
- Sample type
- Human
- Protocol
- Protocol
