Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- BS7188 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- DEFB4 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human DEFB4.
- Description
- ÉÇ-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, ÉÇ-defensins are developmentally regulated. Unlike the other previously described human ÉÇ-defensins, human ÉÇ-defensin 4 (hBD-4) expression is restricted to a few tissues, with highest expression in testis. A restricted pattern is also exhibited by mouse ÉÇ-defensin 4. Rat ÉÇ-defensin 4 (also desiganated BD-4, RBD-4, BD-2, and RBD-2) is developmentally regulated in the lung and is predominantly expressed in the lung and, to a lesser extent, in the trachea and tongue. It exhibits a regulation pattern similar to that of specific genes involved in host defense around the time of birth. The selectivity in both expression pattern and antimicrobial activity of human ÉÇ-defensin 4 suggests that it is best suited to act at the epithelial locations where it is expressed.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
No comments: Submit comment
No validations: Submit validation data