Tissue expression
Cell line expression
Protein structure
ATF6B
Activating transcription factor 6 betaCREBL1, G13
The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Top validated antibodies |
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Proteintech Group | ![]() |
16 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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NovoPro Bioscience Inc. | ![]() |
Polyclonal |
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LSBio | ![]() |
Polyclonal |
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antibodies-online | ![]() |
1 references | Polyclonal |
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