Antibody data
- Antibody Data
- Antigen structure
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- Product number
- DPABH-20827 - Provider product page
- Provider
- Creative Diagnostics
- Proper citation
- Creative Diagnostics Cat#DPABH-20827, RRID:AB_2504186
- Product name
- Rabbit Anti-Human NUDT15 Polyclonal Antibody
- Antibody type
- Polyclonal
- Description
- This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 50ul, 100ul
- Storage
- Store at -20°C. Avoid freeze / thaw cycles.
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