BS6249

antibody from Bioworld Technology, Inc
Targeting: DEFB121 DEFB-21
Provider product page for BS6249
Western blot
Immunohistochemistry

Antibody data

Product number
BS6249 - Provider product page
Provider
Bioworld Technology, Inc
Product name
DEFB121 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human DEFB121.
Description
ÉÇ-defensins (also designated BDs, or hBDs in human) are small cationic peptides with broad-spectrum antimicrobial activity against a variety of enveloped viruses, fungi and bacteria. Produced in mucosal epithelia and neutrophils of several species, ÉÇ-defensins are developmentally regulated. The family of ÉÇ-defensin proteins share a common defensin-motif that is characterized by multiple cysteine residues and a highly conserved tertiary structure. Besides playing a significant role in host immune defense, many ÉÇ-defensins also are involved in sperm maturation and capacitation. ÉÇ-defensin 121 is a 76 amino acid secreted protein that most likely contains a signal peptide sequence that requires cleavage by proteolytic enzymes in order to become biologically active. While expressed at low levels in testis, ÉÇ-defensin 121 is abundantly expressed in epididymal caput and corpus and, unlike other ÉÇ-defensins, it does not appear to be regulated by androgens.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
DEFB121 protein structure - BS6249 shown in red.