CABT-B10661

antibody from Creative Diagnostics
Targeting: MID1 FXY, OS, RNF59, TRIM18
Provider product page for CABT-B10661
No application information provided.

Antibody data

Product number
CABT-B10661 - Provider product page
Provider
Creative Diagnostics
Product name
Mouse anti-Human MID1 monoclonal antibody, clone 3D22
Antibody type
Monoclonal
Description
The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the RING-B box-coiled coil (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Multiple different transcript variants are generated by alternate splicing
MID1 protein structure - CABT-B10661 shown in red.