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- References [6]
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- Product number
- 13685-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- BCKDHB antibody
- Antibody type
- Polyclonal
- Description
- BCKDHB antibody (Cat. #13685-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Mitolnc controls cardiac BCAA metabolism and heart hypertrophy by allosteric activation of BCKDH.
Branched-chain amino acids promote thrombocytopoiesis by activating mTOR signaling.
AMPK induces degradation of the transcriptional repressor PROX1 impairing branched amino acid metabolism and tumourigenesis.
Branched-chain amino acid catabolism breaks glutamine addiction to sustain hepatocellular carcinoma progression.
SIRT4 is an early regulator of branched-chain amino acid catabolism that promotes adipogenesis.
MiR-330-5p negatively regulates ovine preadipocyte differentiation by targeting branched-chain aminotransferase 2.
Weiss M, Hettrich S, Hofmann T, Hachim S, Günther S, Braun T, Boettger T
Nucleic acids research 2024 Jun 24;52(11):6629-6646
Nucleic acids research 2024 Jun 24;52(11):6629-6646
Branched-chain amino acids promote thrombocytopoiesis by activating mTOR signaling.
Jiang H, Zhang L, Yang M, Li G, Ding C, Xin M, Dai J, Sun X, Fan X, Sun H, Liu J, Xu Y
Journal of thrombosis and haemostasis : JTH 2023 Nov;21(11):3224-3235
Journal of thrombosis and haemostasis : JTH 2023 Nov;21(11):3224-3235
AMPK induces degradation of the transcriptional repressor PROX1 impairing branched amino acid metabolism and tumourigenesis.
Wang Y, Luo M, Wang F, Tong Y, Li L, Shu Y, Qiao K, Zhang L, Yan G, Liu J, Ji H, Xie Y, Zhang Y, Gao WQ, Liu Y
Nature communications 2022 Nov 24;13(1):7215
Nature communications 2022 Nov 24;13(1):7215
Branched-chain amino acid catabolism breaks glutamine addiction to sustain hepatocellular carcinoma progression.
Yang D, Liu H, Cai Y, Lu K, Zhong X, Xing S, Song W, Zhang Y, Ye L, Zhu X, Wang T, Zhang P, Li ST, Feng J, Jia W, Zhang H, Gao P
Cell reports 2022 Nov 22;41(8):111691
Cell reports 2022 Nov 22;41(8):111691
SIRT4 is an early regulator of branched-chain amino acid catabolism that promotes adipogenesis.
Zaganjor E, Yoon H, Spinelli JB, Nunn ER, Laurent G, Keskinidis P, Sivaloganathan S, Joshi S, Notarangelo G, Mulei S, Chvasta MT, Tucker SA, Kalafut K, van de Ven RAH, Clish CB, Haigis MC
Cell reports 2021 Jul 13;36(2):109345
Cell reports 2021 Jul 13;36(2):109345
MiR-330-5p negatively regulates ovine preadipocyte differentiation by targeting branched-chain aminotransferase 2.
Shi T, Yan X, Qiao L, Li B, Cheng L, Pan Y, Jing J, Cao N, Liu W
Animal science journal = Nihon chikusan Gakkaiho 2018 Jun;89(6):858-867
Animal science journal = Nihon chikusan Gakkaiho 2018 Jun;89(6):858-867
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The BCKDHB antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human BCKDHB. This antibody recognizes human,mouse,rat antigen. The BCKDHB antibody has been validated for the following applications: ELISA, WB analysis.
