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- References [16]
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- Product number
- 12038-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12038-1-AP, RRID:AB_10665363
- Product name
- HURP antibody
- Antibody type
- Polyclonal
- Description
- HURP antibody (Cat. #12038-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Integrating multiple key molecules in uveal melanoma to uncover metastatic and immune microenvironment-related gene signatures.
DLGAP5 regulates malignancy and lenvatinib sensitivity of hepatocellular carcinoma through AKT/mTOR/NF-κB pathway.
DLGAP5 protects glioblastoma cells against DNA damage through E2F1-transcripted RAD51AP1.
TFAP4/DLGAP5 promotes tumor progression and macrophage M2 polarization in prostate cancer by activating the JAK2/STAT3 signaling.
Diverse microtubule-binding repeats regulate TPX2 activities at distinct locations within the spindle.
DLGAP5 upregulates E2F1 to promote prostate adenocarcinoma neuroendocrine differentiation.
Identification of exosome-related genes associated with prognosis and immune infiltration features in pancreatic cancer.
HURP facilitates spindle assembly by stabilizing microtubules and working synergistically with TPX2.
DLGAP5 promotes lung adenocarcinoma growth via upregulating PLK1 and serves as a therapeutic target.
CCDC69 maintains genome integrity by regulating KIF2C/MCAK depolymerase activity and the stability of the chromosomal passenger complex.
Activation of the Anaphase Promoting Complex Restores Impaired Mitotic Progression and Chemosensitivity in Multiple Drug-Resistant Human Breast Cancer.
High Expression of DLGAP5 Indicates Poor Prognosis and Immunotherapy in Lung Adenocarcinoma and Promotes Proliferation through Regulation of the Cell Cycle.
Integrative multi-omics analysis unveils stemness-associated molecular subtypes in prostate cancer and pan-cancer: prognostic and therapeutic significance.
Whole Genome Transcriptomic Analysis of Ovary Granulosa Cells Revealed an Anti-Apoptosis Regulatory Gene DLGAP5 in Polycystic Ovary Syndrome.
Mitotic Acetylation of Microtubules Promotes Centrosomal PLK1 Recruitment and Is Required to Maintain Bipolar Spindle Homeostasis.
Pan-cancer analysis and experiments with cell lines reveal that the slightly elevated expression of DLGAP5 is involved in clear cell renal cell carcinoma progression.
Guo YM, Bai ZP, Wang JQ, Huang J, Wei JH, Han YJ, Liu Y, Ye L
International journal of ophthalmology 2026;19(1):11-24
International journal of ophthalmology 2026;19(1):11-24
DLGAP5 regulates malignancy and lenvatinib sensitivity of hepatocellular carcinoma through AKT/mTOR/NF-κB pathway.
He B, Deng M, Guan R, Mei J, Zou H, Tang Y, Yang Z, Zheng Z, Lin W, Li S, Guo R, Zhao R, Wei W
European journal of medical research 2026 Feb 9;
European journal of medical research 2026 Feb 9;
DLGAP5 protects glioblastoma cells against DNA damage through E2F1-transcripted RAD51AP1.
Liu Y, Chen R, Liu G, Chen J, Zhou J, Chen Y, Li Z, Li Y, Deng L, Cui H
Biochimica et biophysica acta. Molecular basis of disease 2026 Apr 17;1872(6):168265
Biochimica et biophysica acta. Molecular basis of disease 2026 Apr 17;1872(6):168265
TFAP4/DLGAP5 promotes tumor progression and macrophage M2 polarization in prostate cancer by activating the JAK2/STAT3 signaling.
Li S, Dong Q, Ren W, Sun Y, Wang Z, Pan L
Experimental cell research 2025 Oct 1;452(2):114753
Experimental cell research 2025 Oct 1;452(2):114753
Diverse microtubule-binding repeats regulate TPX2 activities at distinct locations within the spindle.
Liang Z, Huang J, Wang Y, Hua S, Jiang K
The Journal of cell biology 2025 Mar 3;224(3)
The Journal of cell biology 2025 Mar 3;224(3)
DLGAP5 upregulates E2F1 to promote prostate adenocarcinoma neuroendocrine differentiation.
Liang L, Shen Z, Zhang K, Zhang C, Dong L, Shi R, Hua L, Zhao R, Feng N
Life sciences 2025 Mar 15;365:123442
Life sciences 2025 Mar 15;365:123442
Identification of exosome-related genes associated with prognosis and immune infiltration features in pancreatic cancer.
Wang J, Qing M, Gui J, Zhong P, Hua H
Discover oncology 2025 Feb 17;16(1):192
Discover oncology 2025 Feb 17;16(1):192
HURP facilitates spindle assembly by stabilizing microtubules and working synergistically with TPX2.
Valdez VA, Ma M, Gouveia B, Zhang R, Petry S
Nature communications 2024 Nov 8;15(1):9689
Nature communications 2024 Nov 8;15(1):9689
DLGAP5 promotes lung adenocarcinoma growth via upregulating PLK1 and serves as a therapeutic target.
Chen M, Zhang S, Wang F, He J, Jiang W, Zhang L
Journal of translational medicine 2024 Feb 27;22(1):209
Journal of translational medicine 2024 Feb 27;22(1):209
CCDC69 maintains genome integrity by regulating KIF2C/MCAK depolymerase activity and the stability of the chromosomal passenger complex.
Fesquet D, Rabeharivelo G, van Dijk J, Prigent C, Morin N, Rouquier S
Scientific reports 2024 Dec 5;14(1):30401
Scientific reports 2024 Dec 5;14(1):30401
Activation of the Anaphase Promoting Complex Restores Impaired Mitotic Progression and Chemosensitivity in Multiple Drug-Resistant Human Breast Cancer.
Lubachowski M, VanGenderen C, Valentine S, Belak Z, Davies GF, Arnason TG, Harkness TAA
Cancers 2024 Apr 30;16(9)
Cancers 2024 Apr 30;16(9)
High Expression of DLGAP5 Indicates Poor Prognosis and Immunotherapy in Lung Adenocarcinoma and Promotes Proliferation through Regulation of the Cell Cycle.
Tang X, Zhou H, Liu Y
Disease markers 2023;2023:9292536
Disease markers 2023;2023:9292536
Integrative multi-omics analysis unveils stemness-associated molecular subtypes in prostate cancer and pan-cancer: prognostic and therapeutic significance.
Zheng K, Hai Y, Xi Y, Zhang Y, Liu Z, Chen W, Hu X, Zou X, Hao J
Journal of translational medicine 2023 Nov 7;21(1):789
Journal of translational medicine 2023 Nov 7;21(1):789
Whole Genome Transcriptomic Analysis of Ovary Granulosa Cells Revealed an Anti-Apoptosis Regulatory Gene DLGAP5 in Polycystic Ovary Syndrome.
Deng Y, Li H, Song Y, Cen J, Zhang Y, Sui Y, Cui D, Li TC, Xu Y, Wang CC, Chung PWJ, Tang T
Frontiers in endocrinology 2022;13:781149
Frontiers in endocrinology 2022;13:781149
Mitotic Acetylation of Microtubules Promotes Centrosomal PLK1 Recruitment and Is Required to Maintain Bipolar Spindle Homeostasis.
Rasamizafy SF, Delsert C, Rabeharivelo G, Cau J, Morin N, van Dijk J
Cells 2021 Jul 22;10(8)
Cells 2021 Jul 22;10(8)
Pan-cancer analysis and experiments with cell lines reveal that the slightly elevated expression of DLGAP5 is involved in clear cell renal cell carcinoma progression.
Feng Y, Li F, Yan J, Guo X, Wang F, Shi H, Du J, Zhang H, Gao Y, Li D, Yao Y, Hu W, Han J, Zhang M, Ding R, Wang X, Huang C, Zhang J
Life sciences 2021 Dec 15;287:120056
Life sciences 2021 Dec 15;287:120056
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HURP antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HURP. This antibody recognizes human antigen. The HURP antibody has been validated for the following applications: ELISA, WB analysis.
